PubMed 25433078
Referenced in: none
Automatically associated channels: ClC4
Title: In the beginning: a personal reminiscence on the origin and legacy of ClC-0, the 'Torpedo Cl(-) channel'.
Authors: Christopher Miller
Journal, date & volume: J. Physiol. (Lond.), 2015 Sep 15 , 593, 4085-90
PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/25433078
Abstract
This unapologetically subjective essay recalls the Torpedo Cl(-) channel in the years when it had neither a molecular identity nor proper name (ClC-0), and membership in a large superfamily. I discuss the circumstances surrounding its discovery and subsequent research through the 1980s that revealed its unusual molecular architecture and other strange mechanistic characteristics.