PubMed 27229313

Referenced in Channelpedia wiki pages of: none

Automatically associated channels: Kv10.1

Title: Electrophysiologist shows a cation channel function of MLKL.

Authors: Yingying Zhang, Jiahuai Han

Journal, date & volume: Cell Res., 2016 Jun , 26, 643-4

PubMed link:

Whether mixed lineage kinase domain-like (MLKL) mediates necroptosis by forming ion channel, none-selective pore, or simply by disrupting plasma membrane is unclear. In a paper published in recent issue of Cell Research, Xia et al. showed that MLKL functions as a novel class of cation channel.