PubMed 25637012

Referenced in Channelpedia wiki pages of: none

Automatically associated channels: Kir2.3

Title: Spherical β-cyclodextrin-silica hybrid materials for multifunctional chiral stationary phases.

Authors: Litao Wang, Shuqing Dong, Feng Han, Yingwei Zhao, Xia Zhang, Xiaoli Zhang, Hongdeng Qiu, Liang Zhao

Journal, date & volume: J Chromatogr A, 2015 Feb 27 , 1383, 70-8

PubMed link:

Spherical β-CD-silica hybrid materials have been prepared successfully by simple one-pot polymerization, which provide a new strategy to construct new type of HPLC chiral stationary phases. Various β-CD, ethane, triazinyl and 3,5-dimethylphenyl functional groups that can provide multiple interactions were introduced into the pore channels and pore wall framework of mesoporous materials, respectively. The materials towards some chiral, acidic, anilines and phenols compounds showed multiple chromatographic separation functions including racemic resolution, anion exchange and achiral separations with a typical feature of normal/reversed phase chromatography. Multi-tasking including racemic resolution and achiral separations for selected compounds were performed simultaneously on a chiral chromatographic column. The multifunctional character of materials arises from the multiple interactions including hydrophobic interaction, π-π interaction, anion exchange, inclusion interaction and hydrogen bonding interaction.