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PubMed 25958864


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Automatically associated channels: Kv10.1



Title: Double-sided Microfluidic Device for Speciation Analysis of Iron in Water Samples: Towards Greener Analytical Chemistry.

Authors: Napaporn Youngvises, Porapichcha Thanurak, Thanatcha Chaida, Jaroon Jukmunee, Awadh Alsuhaimi

Journal, date & volume: Anal Sci, 2015 , 31, 365-70

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/25958864


Abstract
Microfluidics minimize the amounts of reagents and generate less waste. While microdevices are commonly single-sided, producing a substrate with microchannels on multiple surfaces would increase their usefulness. Herein, a polymethymethacrylate substrate incorporating microchannel structures on two sides was sandwiched between two polydimethylsiloxane sheets to create a multi-analysis device, which was used for the spectrophotometric analysis of the ferrous ion (Fe(2+)) and the ferric ion (Fe(3+)), by utilizing colorimetric detection. To monitor the signals from both channel networks, dual optical sensors were integrated into the system. The linear ranges for Fe(2+) and Fe(3+) analyses were 0.1 - 20 mg L(-1) (R(2) = 0.9988) and 1.0 - 40 mg L(-1) (R(2) = 0.9974), respectively. The detection limits for Fe(2+) and Fe(3+) were 0.1 and 0.5 mg L(-1), respectively. The percent recoveries of Fe(2+) and Fe(3+) were 93.5 - 104.3 with an RSD < 8%. The microdevice demonstrated capabilities for simultaneous analysis, low waste generation (7.2 mL h(-1)), and high sample throughput (180 h(-1)), making it ideal for greener analytical chemistry applications.