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PubMed 24485399


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Automatically associated channels: Kir1.1 , Kir6.2



Title: Gender-dependent associations of CDKN2A/2B, KCNJ11, POLI, SLC30A8, and TCF7L2 variants with type 2 diabetes in (North African) Tunisian Arabs.

Authors: Amira Turki, Ghadeer S Al-Zaben, Moncef Khirallah, Hela Marmouch, Touhami Mahjoub, Wassim Y Almawi

Journal, date & volume: Diabetes Res. Clin. Pract., 2014 Mar , 103, e40-3

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/24485399


Abstract
We investigated the impact of gender on T2DM association with confirmed susceptibility loci. CDKN2A/2B rs10811661, KCNJ11 rs5219, and TCF7L2 rs7903146 were associated with T2DM in females, while POLI rs488846 was associated with T2DM among males; the association of SLC30A8 rs13266634 and TCF7L2 rs4506565, rs12243326, and rs12255372 with T2DM was gender-independent.