Referenced in: none

Automatically associated channels: TRP , TRPV , TRPV1

Title: Die another day: a painless path to longevity.

Authors: Sophie M Steculorum, Jens C Brüning

Journal, date & volume: Cell, 2014 May 22 , 157, 1004-6

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/24855937

Abstract
Riera et al. identify a neuroendocrine circuit that controls longevity and the age-dependent onset of metabolic decline via the pain-transducing channel TRPV1. Thus, pharmacological inhibition of TRPV1 may provide a new approach to treat not only metabolic disorders but also a broader range of age-related pathologies.