Referenced in: none

Automatically associated channels: Kv10.1

Title: Prostate cancer cells alter the nature of their calcium influx to promote growth and acquire apoptotic resistance.

Authors: Gregory R Monteith

Journal, date & volume: Cancer Cell, 2014 Jul 14 , 26, 1-2

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/25026203

Abstract
In this issue of Cancer Cell, Dubois and colleagues report a remodeling of calcium influx in prostate cancer cells. Prostate cancer cells can undergo an oncogenic switch from a calcium influx pathway capable of inducing apoptosis involving ORAI1 channels to a pro-proliferative calcium influx pathway involving ORAI1/3 heteromeric channels.