Channelpedia

PubMed 25158850


Referenced in Channelpedia wiki pages of: none

Automatically associated channels: TRP , TRPV , TRPV1



Title: Neuronal osmotransduction: push-activating TRPV1 with microtubules.

Authors: Marta Andrés, Martin C Göpfert

Journal, date & volume: Dev. Cell, 2014 Aug 25 , 30, 363-4

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/25158850


Abstract
Regulating the osmotic pressure of our body fluids relies on osmosensory neurons that depolarize when their volume decreases. Recently in Neuron, Prager-Khoutorsky et al. (2014) report that this depolarization arises from direct interactions between the transient receptor potential channel TRPV1 and microtubules, which seem to directly push open the channel.