Referenced in: none

Automatically associated channels: Kv10.1 , TRP , TRPM , TRPM3

Title: Targeting ions-induced autophagy in cancer.

Authors: Francesco Cecconi, Marja Jäättelä

Journal, date & volume: Cancer Cell, 2014 Nov 10 , 26, 599-600

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/25517744

Abstract
Autophagy is an important cellular homeostasis pathway, but its role in cancer remains to be fully elucidated. In this issue of Cancer Cell, Hall and colleagues describe a TRPM3-dependent autophagy pathway that is selectively important for clear cell renal cell carcinoma and can be effectively inhibited.