Referenced in: none

Automatically associated channels: Kir1.1 , Kv11.1

Title: Discovery of a novel sub-class of ROMK channel inhibitors typified by 5-(2-(4-(2-(4-(1H-Tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-one.

Authors: Haifeng Tang, Reynald K de Jesus, Shawn P Walsh, Yuping Zhu, Yan Yan, Birgit T Priest, Andrew M Swensen, Magdalena Alonso-Galicia, John P Felix, Richard M Brochu, Timothy Bailey, Brande Thomas-Fowlkes, Xiaoyan Zhou, Lee-Yuh Pai, Caryn Hampton, Melba Hernandez, Karen Owens, Sophie Roy, Gregory J Kaczorowski, Lihu Yang, Maria L Garcia, Alexander Pasternak

Journal, date & volume: Bioorg. Med. Chem. Lett., 2013 Nov 1 , 23, 5829-32

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/24075732

Abstract