Referenced in: none

Automatically associated channels: TRP

Title: TRP channel blamed for burning cold after a tropical fish meal.

Authors: Thomas Voets

Journal, date & volume: EMBO J., 2012 Oct 3 , 31, 3785-7

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/22960637

Abstract
EMBO J (2012) 31 19, 3795–3808 doi:; DOI: 10.1038/emboj.2012.207; published online July 31 2012 Ciguatera is one of the most common forms of food poisoning, occurring after consumption of fish contaminated with ciguatoxins. New work by Vetter et al (2012) reveals the key molecular players that underlie the altered temperature sensation associated with ciguatera. In particular, they show that ciguatoxins act on sensory neurons that express TRPA1, an ion channel implicated in the detection of noxious cold.