Channelpedia

PubMed 22293401


Referenced in Channelpedia wiki pages of: none

Automatically associated channels: Kv10.1



Title: A novel role for microglia in minimizing excitotoxicity.

Authors: Mariko L Howe, Ben A Barres

Journal, date & volume: BMC Biol., 2012 , 10, 7

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/22293401


Abstract
Microglia are the abundant, resident myeloid cells of the central nervous system (CNS) that become rapidly activated in response to injury or inflammation. While most studies of microglia focus on this phenomenon, little is known about the function of 'resting' microglia, which possess fine, branching cellular processes. Biber and colleagues, in a recent paper in Journal of Neuroinflammation, report that ramified microglia can limit excitotoxicity, an important insight for understanding mechanisms that limit neuron death in CNS disease.