Referenced in: none

Automatically associated channels: Kv1.3

Title: Potassium channels, memory T cells, and multiple sclerosis.

Authors: Christine Beeton, K George Chandy

Journal, date & volume: , 2005 Dec , 11, 550-62

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/16282596

Abstract
Multiple sclerosis is a chronic inflammatory autoimmune disease of the central nervous system characterized by demyelination and axonal damage that result in disabling neurological deficits. Here the authors explain the rationale for the use of inhibitors of the Kv1.3 K+ channel in immune cells as a therapy for multiple sclerosis and other autoimmune disorders.