Channelpedia

PubMed 12691656


Referenced in: none

Automatically associated channels: ClC1 , ClC2 , ClC4 , Kv10.1



Title: The poststructural festivities begin.

Authors: Merritt Maduke, Joseph A Mindell

Journal, date & volume: Neuron, 2003 Apr 10 , 38, 1-3

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/12691656


Abstract
ClC chloride channels orchestrate the movement of chloride necessary for proper neuronal, muscular, cardiovascular, and epithelial function. In this issue of Neuron, Jentsch, Pusch, and colleagues use the structure of a bacterial ClC homolog to guide a mutagenic analysis of inhibitor binding to ClC-0, ClC-1, and ClC-2.