PubMed 12691656
Referenced in: none
Automatically associated channels: ClC1 , ClC2 , ClC4 , Kv10.1
Title: The poststructural festivities begin.
Authors: Merritt Maduke, Joseph A Mindell
Journal, date & volume: Neuron, 2003 Apr 10 , 38, 1-3
PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/12691656
Abstract
ClC chloride channels orchestrate the movement of chloride necessary for proper neuronal, muscular, cardiovascular, and epithelial function. In this issue of Neuron, Jentsch, Pusch, and colleagues use the structure of a bacterial ClC homolog to guide a mutagenic analysis of inhibitor binding to ClC-0, ClC-1, and ClC-2.