Channelpedia

PubMed 19712222


Referenced in: none

Automatically associated channels: ClC4 , ClCA1



Title: Interleukin 4 receptor alpha (IL4R) and calcium-activated chloride channel 1 (CLCA1) genes map to donkey chromosome.

Authors: M Bugno, E Slota, W Witarski, V Gerber, J Klukowska-Roetzler

Journal, date & volume: Hereditas, 2009 Jun , 146, 118-21

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/19712222


Abstract
The results obtained in the present study enabled the physical map of the donkey genome to be extended with markers associated with recurrent airway obstruction (RAO), a major performance-limiting disease of Equidae. The equine BAC clone containing the IL4R and CLCA1 genes were localized to EAS 14q13 and EAS 6q15 respectlivy by fluorescent in situ hybridization. Identification of their locus confirmed the distribution of syntenic regions between the domestic horse and the domestic donkey within the chromosomes analysed.