Channelpedia

Localization of the gamma-subunit of the skeletal muscle L-type voltage-dependent calcium channel gene (CACNLG) to human chromosome band 17q24 by in situ hybridization and identification of a polymorphic repetitive DNA sequence at the gene locus.


Authors: D E Iles, B Segers, D O Weghuis, R Suikerbuijk, B Wieringa

Journal, date & volume: Cytogenet. Cell Genet., 1993 , 64, 227-30

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/8404045

Channelpedia reference in: cacng1

Abstract
The skeletal muscle dihydropyridine receptor consists of five subunits and fulfils an essential role in excitation-contraction coupling. A genomic clone for the human gamma subunit was used to map the gene (CACNLG) to chromosome band 17q24 by in situ hybridization. Contained within the gene is a 416-bp polymorphic repetitive DNA element that is potentially useful as a genetic marker.