Channelpedia

Kir3.4 Channel

286 automatically matched literature references

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Williams TA et al. Genotype-Specific Steroid Profiles Associated With Aldosterone-Producing Adenomas.
Hypertension, 2016 Jan , 67 (139-45).

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Bukiya AN et al. Cholesterol increases the open probability of cardiac KACh currents.
Biochim. Biophys. Acta, 2015 Oct , 1848 (2406-13).

11

Åkerström T et al. Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas.
Endocr. Relat. Cancer, 2015 Oct , 22 (735-44).

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Fernandes-Rosa FL et al. Different Somatic Mutations in Multinodular Adrenals With Aldosterone-Producing Adenoma.
Hypertension, 2015 Nov , 66 (1014-22).

15

Thomson SJ et al. Identification of the Intracellular Na+ Sensor in Slo2.1 Potassium Channels.
J. Biol. Chem., 2015 Jun 5 , 290 (14528-35).

16

Fernandes-Rosa FL et al. Functional histopathological markers of aldosterone producing adenoma and somatic KCNJ5 mutations.
Mol. Cell. Endocrinol., 2015 Jun 15 , 408 (220-6).

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Monticone S et al. 6C.03: A CASE OF SEVERE HYPERALDOSTERONISM CAUSED BY A DE NOVO KCNJ5 MUTATION.
J. Hypertens., 2015 Jun , 33 Suppl 1 (e79-80).

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Duan K et al. Clinicopathologic Correlates of Primary Aldosteronism.
Arch. Pathol. Lab. Med., 2015 Jul , 139 (948-54).

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Cheng CJ et al. Novel KCNJ5 mutations in sporadic aldosterone-producing adenoma reduce Kir3.4 membrane abundance.
J. Clin. Endocrinol. Metab., 2015 Jan , 100 (E155-63).

21

Zennaro MC et al. An update on novel mechanisms of primary aldosteronism.
J. Endocrinol., 2015 Feb , 224 (R63-77).

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Zhang J et al. [Sequence analysis of coding regions of KCNJ5 gene in unilateral adrenal hyperplasia].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2015 Feb , 32 (21-5).

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Monticone S et al. Immunohistochemical, genetic and clinical characterization of sporadic aldosterone-producing adenomas.
Mol. Cell. Endocrinol., 2015 Aug 15 , 411 (146-54).

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Lenzini L et al. A Meta-Analysis of Somatic KCNJ5 K(+) Channel Mutations In 1636 Patients With an Aldosterone-Producing Adenoma.
J. Clin. Endocrinol. Metab., 2015 Aug , 100 (E1089-95).

27

Markou A et al. Stress-induced Aldosterone Hyper-Secretion in a Substantial Subset of Patients With Essential Hypertension.
J. Clin. Endocrinol. Metab., 2015 Aug , 100 (2857-64).

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Cannon SC Channelopathies of skeletal muscle excitability.
Compr Physiol, 2015 Apr , 5 (761-90).

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Lenzini L et al. The molecular basis of primary aldosteronism: from chimeric gene to channelopathy.
Curr Opin Pharmacol, 2015 Apr , 21 (35-42).

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Boulkroun S et al. Molecular and Cellular Mechanisms of Aldosterone Producing Adenoma Development.
Front Endocrinol (Lausanne), 2015 , 6 (95).

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Zhang H et al. [Progress on genetic basis of primary aldosteronism].
Zhejiang Da Xue Xue Bao Yi Xue Ban, 2014 Sep , 43 (612-8).

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Felizola SJ et al. Voltage-gated calcium channels in the human adrenal and primary aldosteronism.
J. Steroid Biochem. Mol. Biol., 2014 Oct , 144 Pt B (410-6).

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Kokunai Y et al. A Kir3.4 mutation causes Andersen-Tawil syndrome by an inhibitory effect on Kir2.1.
Neurology, 2014 Mar 25 , 82 (1058-64).

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Fischer E et al. Novel genes in primary aldosteronism.
Curr Opin Endocrinol Diabetes Obes, 2014 Jun , 21 (154-8).

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Gomez-Sanchez CE et al. Somatic mutations of the ATP1A1 gene and aldosterone-producing adenomas.
Mol. Cell. Endocrinol., 2014 Dec 10 , ().

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Fernandes-Rosa FL et al. Genetic spectrum and clinical correlates of somatic mutations in aldosterone-producing adenoma.
Hypertension, 2014 Aug , 64 (354-61).

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Al-Salameh A et al. Overview of the genetic determinants of primary aldosteronism.
Appl Clin Genet, 2014 , 7 (67-79).

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Funder JW Genetics of primary aldosteronism.
Front Horm Res, 2014 , 43 (70-8).

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Kumar M et al. Focus on Kir7.1: physiology and channelopathy.
Channels (Austin), 2014 , 8 (488-95).

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Williams TA et al. Somatic ATP1A1, ATP2B3, and KCNJ5 Mutations in Aldosterone-Producing Adenomas.
Hypertension, 2013 Sep 30 , ().

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Monticone S et al. a Novel Y152C KCNJ5 mutation responsible for familial hyperaldosteronism type III.
J. Clin. Endocrinol. Metab., 2013 Nov , 98 (E1861-5).

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Boulkroun S et al. KCNJ5 mutations in aldosterone producing adenoma and relationship with adrenal cortex remodeling.
Mol. Cell. Endocrinol., 2013 May 22 , 371 (221-7).

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Stowasser M Primary aldosteronism and potassium channel mutations.
Curr Opin Endocrinol Diabetes Obes, 2013 Jun , 20 (170-9).

76

Ravens U et al. Atrial selectivity of antiarrhythmic drugs.
J. Physiol. (Lond.), 2013 Jul 16 , ().

78

Zennaro MC et al. Genetics of mineralocorticoid excess: an update for clinicians.
Eur. J. Endocrinol., 2013 Jul , 169 (R15-25).

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Mulatero P et al. Role of KCNJ5 in familial and sporadic primary aldosteronism.
Nat Rev Endocrinol, 2013 Feb , 9 (104-12).

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Kang YA et al. [Expression of GIRK4 gene in kidney tissues of obese rat].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao, 2013 Feb , 35 (36-9).

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Velarde-Miranda C et al. Regulation of aldosterone biosynthesis by the Kir3.4 (KCNJ5) potassium channel.
Clin. Exp. Pharmacol. Physiol., 2013 Dec , 40 (895-901).

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Holmegard HN et al. Genetic variation in the parasympathetic signaling pathway in patients with reflex syncope.
Genet. Mol. Res., 2013 , 12 (2601-10).

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Bar-Lev A et al. Genetics of adrenocortical disease: an update.
Curr Opin Endocrinol Diabetes Obes, 2012 Jun , 19 (159-67).

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Li N et al. Influence of age on the association of GIRK4 with metabolic syndrome.
Ann. Clin. Biochem., 2012 Jul , 49 (369-76).

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Scholl UI et al. Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5.
Proc. Natl. Acad. Sci. U.S.A., 2012 Feb 14 , 109 (2533-8).

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Li NF et al. [Association between GIRK4 gene polymorphisms and insulin resistance in Xinjiang Uygur population].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2012 Dec , 29 (715-9).

108

Yamada M et al. KCNJ5 mutations in aldosterone- and cortisol-co-secreting adrenal adenomas.
Endocr. J., 2012 Aug 31 , 59 (735-41).

109

Monticone S et al. Effect of KCNJ5 mutations on gene expression in aldosterone-producing adenomas and adrenocortical cells.
J. Clin. Endocrinol. Metab., 2012 Aug , 97 (E1567-72).

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Kang YA et al. Advances in research on G protein-coupled inward rectifier K(+) channel gene.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao, 2012 Aug , 34 (426-30).

113

Funder JW The genetic basis of primary aldosteronism.
Curr. Hypertens. Rep., 2012 Apr , 14 (120-4).

115

Taguchi R et al. Expression and mutations of KCNJ5 mRNA in Japanese patients with aldosterone-producing adenomas.
J. Clin. Endocrinol. Metab., 2012 Apr , 97 (1311-9).

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Chopra N et al. Genetics of sudden cardiac death syndromes.
, 2011 Mar 22 , ().

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Zennaro MC et al. Mutations in KCNJ5 gene cause hyperaldosteronism.
Circ. Res., 2011 Jun 10 , 108 (1417-8).

123

Yang Y et al. Identification of a Kir3.4 mutation in congenital long QT syndrome.
Am. J. Hum. Genet., 2010 Jun 11 , 86 (872-80).

127

Rosenhouse-Dantsker A et al. Comparative analysis of cholesterol sensitivity of Kir channels: Role of the CD loop.
Channels (Austin), 2010 Jan 20 , 4 ().

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Walsh KB A real-time screening assay for GIRK1/4 channel blockers.
J Biomol Screen, 2010 Dec , 15 (1229-37).

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Ishihara K et al. Heteromeric assembly of inward rectifier channel subunit Kir2.1 with Kir3.1 and with Kir3.4.
Biochem. Biophys. Res. Commun., 2009 Mar 20 , 380 (832-7).

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Robitaille M et al. Intracellular trafficking and assembly of specific Kir3 channel/G protein complexes.
Cell. Signal., 2009 Apr , 21 (488-501).

140

Jin T et al. Stoichiometry of Kir channels with phosphatidylinositol bisphosphate.
Channels (Austin), 2008 Jan-Feb , 2 (19-33).

142

Zhao Z et al. Molecular basis for genistein-induced inhibition of Kir2.3 currents.
Pflugers Arch., 2008 May , 456 (413-23).

144

Perry CA et al. Predisposition to late-onset obesity in GIRK4 knockout mice.
Proc. Natl. Acad. Sci. U.S.A., 2008 Jun 10 , 105 (8148-53).

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Ehrlich JR Inward rectifier potassium currents as a target for atrial fibrillation therapy.
J. Cardiovasc. Pharmacol., 2008 Aug , 52 (129-35).

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Rosenhouse-Dantsker A et al. Potassium channel gating in the absence of the highly conserved glycine of the inner transmembrane helix.
Channels (Austin), 2007 May-Jun , 1 (189-97).

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Lopes CM et al. Protein kinase A modulates PLC-dependent regulation and PIP2-sensitivity of K+ channels.
Channels (Austin), 2007 Mar-Apr , 1 (124-34).

153

Liu B et al. Selective inhibition of Kir currents by antihistamines.
Eur. J. Pharmacol., 2007 Mar 8 , 558 (21-6).

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Calloe K et al. Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.
Biochem. Biophys. Res. Commun., 2007 Dec 28 , 364 (889-95).

157

Kawano T et al. Interaction of Galphaq and Kir3, G protein-coupled inwardly rectifying potassium channels.
Mol. Pharmacol., 2007 Apr , 71 (1179-84).

158

Steinecker B et al. The GIRK1 brain variant GIRK1d and its functional impact on heteromultimeric GIRK channels.
J. Recept. Signal Transduct. Res., 2007 , 27 (369-82).

160

Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by the antidepressant paroxetine.
J. Pharmacol. Sci., 2006 Nov , 102 (278-87).

161

Thomas AM et al. Differential phosphoinositide binding to components of the G protein-gated K+ channel.
J. Membr. Biol., 2006 May , 211 (43-53).

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Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil.
Neuropsychopharmacology, 2006 Mar , 31 (516-24).

165

Chen X et al. Inhibition of a background potassium channel by Gq protein alpha-subunits.
Proc. Natl. Acad. Sci. U.S.A., 2006 Feb 28 , 103 (3422-7).

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Kanjhan R et al. Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner.
J. Pharmacol. Exp. Ther., 2005 Sep , 314 (1353-61).

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Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Neuropsychopharmacology, 2004 Oct , 29 (1841-51).

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Nikolov EN et al. Functional characterization of a small conductance GIRK channel in rat atrial cells.
Biophys. J., 2004 Nov , 87 (3122-36).

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Nikolov EN et al. Coordination of membrane excitability through a GIRK1 signaling complex in the atria.
J. Biol. Chem., 2004 May 28 , 279 (23630-6).

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Mao J et al. Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase C.
Proc. Natl. Acad. Sci. U.S.A., 2004 Jan 27 , 101 (1087-92).

184

Bender K et al. Acute desensitization of GIRK current in rat atrial myocytes is related to K+ current flow.
J. Physiol. (Lond.), 2004 Dec 1 , 561 (471-83).

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Wellner-Kienitz MC et al. Voltage dependence of ATP-dependent K+ current in rat cardiac myocytes is affected by IK1 and IK(ACh).
J. Physiol. (Lond.), 2004 Dec 1 , 561 (459-69).

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Cader ZM et al. Significant linkage to migraine with aura on chromosome 11q24.
Hum. Mol. Genet., 2003 Oct 1 , 12 (2511-7).

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Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac).
Br. J. Pharmacol., 2003 Mar , 138 (1119-28).

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Mao J et al. Inhibition of G-protein-coupled inward rectifying K+ channels by intracellular acidosis.
J. Biol. Chem., 2003 Feb 28 , 278 (7091-8).

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Kobayashi T et al. Functional characterization of an endogenous Xenopus oocyte adenosine receptor.
Br. J. Pharmacol., 2002 Jan , 135 (313-22).

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Wickman K et al. Structural characterization of the mouse Girk genes.
Gene, 2002 Feb 6 , 284 (241-50).

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Bettahi I et al. Contribution of the Kir3.1 subunit to the muscarinic-gated atrial potassium channel IKACh.
J. Biol. Chem., 2002 Dec 13 , 277 (48282-8).

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Dobrzynski H et al. Effects of ACh and adenosine mediated by Kir3.1 and Kir3.4 on ferret ventricular cells.
Am. J. Physiol. Heart Circ. Physiol., 2002 Aug , 283 (H615-30).

211

Shui Z et al. Evidence of involvement of GIRK1/GIRK4 in long-term desensitization of cardiac muscarinic K+ channels.
Am. J. Physiol. Heart Circ. Physiol., 2001 Jun , 280 (H2554-62).

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Medina I et al. A switch mechanism for G beta gamma activation of I(KACh).
J. Biol. Chem., 2000 Sep 22 , 275 (29709-16).

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Mark MD et al. G-protein mediated gating of inward-rectifier K+ channels.
Eur. J. Biochem., 2000 Oct , 267 (5830-6).

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Yakubovich D et al. Slow modal gating of single G protein-activated K+ channels expressed in Xenopus oocytes.
J. Physiol. (Lond.), 2000 May 1 , 524 Pt 3 (737-55).

230

Bradley KK et al. Kir3.1/3.2 encodes an I(KACh)-like current in gastrointestinal myocytes.
Am. J. Physiol. Gastrointest. Liver Physiol., 2000 Feb , 278 (G289-96).

234

Wickman K et al. Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4.
J. Neurosci., 2000 Aug 1 , 20 (5608-15).

236

Crossen PE et al. Identification of amplified genes in a patient with acute myeloid leukemia and double minute chromosomes.
Cancer Genet. Cytogenet., 1999 Sep , 113 (126-33).

241

Otero AS et al. Wild-type NM23-H1, but not its S120 mutants, suppresses desensitization of muscarinic potassium current.
Biochim. Biophys. Acta, 1999 Mar 8 , 1449 (157-68).

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Rohács T et al. Distinct specificities of inwardly rectifying K(+) channels for phosphoinositides.
J. Biol. Chem., 1999 Dec 17 , 274 (36065-72).

254

Krapivinsky G et al. Gbeta binding to GIRK4 subunit is critical for G protein-gated K+ channel activation.
J. Biol. Chem., 1998 Jul 3 , 273 (16946-52).

256

Wickman K et al. Abnormal heart rate regulation in GIRK4 knockout mice.
Neuron, 1998 Jan , 20 (103-14).

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264

Wickman K et al. Partial structure, chromosome localization, and expression of the mouse Girk4 gene.
Genomics, 1997 Mar 15 , 40 (395-401).

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Wischmeyer E et al. Subunit interactions in the assembly of neuronal Kir3.0 inwardly rectifying K+ channels.
Mol. Cell. Neurosci., 1997 , 9 (194-206).

272

Karschin C et al. Ontogeny of gene expression of Kir channel subunits in the rat.
Mol. Cell. Neurosci., 1997 , 10 (131-48).

276

Silverman SK et al. Subunit stoichiometry of a heteromultimeric G protein-coupled inward-rectifier K+ channel.
J. Biol. Chem., 1996 Nov 29 , 271 (30524-8).

278

Sui JL et al. Na+ activation of the muscarinic K+ channel by a G-protein-independent mechanism.
J. Gen. Physiol., 1996 Nov , 108 (381-91).

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Chan KW et al. A recombinant inwardly rectifying potassium channel coupled to GTP-binding proteins.
J. Gen. Physiol., 1996 Mar , 107 (381-97).

283

Silverman SK et al. A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation.
Proc. Natl. Acad. Sci. U.S.A., 1996 Dec 24 , 93 (15429-34).