Channelpedia

Kir3.2 Channel

347 automatically matched literature references

2

Waterman M et al. Predictors of Outcome in Ulcerative Colitis.
Inflamm. Bowel Dis., 2015 Sep , 21 (2097-105).

3

Adney SK et al. A Critical Gating Switch at a Modulatory Site in Neuronal Kir3 Channels.
J. Neurosci., 2015 Oct 21 , 35 (14397-405).

4

Hablitz LM et al. GIRK Channels Mediate the Nonphotic Effects of Exogenous Melatonin.
J. Neurosci., 2015 Nov 11 , 35 (14957-65).

10

Thomson SJ et al. Identification of the Intracellular Na+ Sensor in Slo2.1 Potassium Channels.
J. Biol. Chem., 2015 Jun 5 , 290 (14528-35).

11

Tsantoulas C Emerging potassium channel targets for the treatment of pain.
Curr Opin Support Palliat Care, 2015 Jun , 9 (147-54).

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Bagriantsev SN et al. Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold libraries.
ACS Chem Neurosci, 2014 Sep 17 , 5 (812-22).

25

Xiong Y et al. Serum antibodies to microbial antigens for Crohn's disease progression: a meta-analysis.
Eur J Gastroenterol Hepatol, 2014 Jul , 26 (733-42).

30

Lalive AL et al. Firing modes of dopamine neurons drive bidirectional GIRK channel plasticity.
J. Neurosci., 2014 Apr 9 , 34 (5107-14).

32

Hartfield EM et al. Physiological characterisation of human iPS-derived dopaminergic neurons.
PLoS ONE, 2014 , 9 (e87388).

35

Ramos-Hunter SJ et al. Discovery and SAR of a novel series of GIRK1/2 and GIRK1/4 activators.
Bioorg. Med. Chem. Lett., 2013 Sep 15 , 23 (5195-8).

38

Whorton MR et al. X-ray structure of the mammalian GIRK2-βγ G-protein complex.
Nature, 2013 Jun 13 , 498 (190-7).

39

Zylbergold P et al. A novel, radiolabel-free pulse chase strategy to study Kir3 channel ontogeny.
J. Recept. Signal Transduct. Res., 2013 Jun , 33 (144-52).

42

Aguado C et al. Differential maturation of GIRK2-expressing neurons in the mouse cerebellum.
J. Chem. Neuroanat., 2013 Jan , 47 (79-89).

43

Richard-Lalonde M et al. Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors.
Mol. Pharmacol., 2013 Feb , 83 (416-28).

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Edenberg HJ et al. Genetics and alcoholism.
Nat Rev Gastroenterol Hepatol, 2013 Aug , 10 (487-94).

55

Best TK et al. Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome.
Exp. Neurol., 2012 Feb , 233 (749-57).

57

Wydeven N et al. Structural elements in the Girk1 subunit that potentiate G protein-gated potassium channel activity.
Proc. Natl. Acad. Sci. U.S.A., 2012 Dec 26 , 109 (21492-7).

59

Reyes S et al. GIRK2 expression in dopamine neurons of the substantia nigra and ventral tegmental area.
J. Comp. Neurol., 2012 Aug 15 , 520 (2591-607).

62

Lü Q et al. Identification of GIRK2-4 subunits in human esophageal smooth muscle cells.
Mol Med Report, 2011 Sep-Oct , 4 (941-5).

66

Liu C et al. Genetic analysis of Down syndrome-associated heart defects in mice.
Hum. Genet., 2011 Nov , 130 (623-32).

69

Yamamoto T et al. Clinical manifestations of the deletion of Down syndrome critical region including DYRK1A and KCNJ6.
Am. J. Med. Genet. A, 2011 Jan , 155A (113-9).

70

Lazary J et al. Epistatic interaction of CREB1 and KCNJ6 on rumination and negative emotionality.
Eur Neuropsychopharmacol, 2011 Jan , 21 (63-70).

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Inanobe A et al. Inverse agonist-like action of cadmium on G-protein-gated inward-rectifier K(+) channels.
Biochem. Biophys. Res. Commun., 2011 Apr 8 , 407 (366-71).

77

Arora D et al. Altered neurotransmission in the mesolimbic reward system of Girk mice.
J. Neurochem., 2010 Sep 1 , 114 (1487-97).

78

Nassirpour R et al. Morphine- and CaMKII-dependent enhancement of GIRK channel signaling in hippocampal neurons.
J. Neurosci., 2010 Oct 6 , 30 (13419-30).

79

Lötsch J et al. Pharmacogenetics of new analgesics.
, 2010 Oct 13 , ().

85

Styer AM et al. G protein {beta}{gamma} gating confers volatile anesthetic inhibition to Kir3 channels.
J. Biol. Chem., 2010 Dec 31 , 285 (41290-9).

89

Cramer NP et al. GABAB-GIRK2-mediated signaling in Down syndrome.
Adv. Pharmacol., 2010 , 58 (397-426).

93

Aryal P et al. A discrete alcohol pocket involved in GIRK channel activation.
Nat. Neurosci., 2009 Jun 28 , ().

98

Chung HJ et al. G protein-activated inwardly rectifying potassium channels mediate depotentiation of long-term potentiation.
Proc. Natl. Acad. Sci. U.S.A., 2009 Jan 13 , 106 (635-40).

99

McGovern DP et al. MAGI2 genetic variation and inflammatory bowel disease.
Inflamm. Bowel Dis., 2009 Jan , 15 (75-83).

101

Robitaille M et al. Intracellular trafficking and assembly of specific Kir3 channel/G protein complexes.
Cell. Signal., 2009 Apr , 21 (488-501).

104

Mundwiler ML et al. Inflammatory bowel disease serologies in ankylosing spondylitis patients: a pilot study.
Arthritis Res. Ther., 2009 , 11 (R177).

105

Saenz del Burgo L et al. Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain.
J. Comp. Neurol., 2008 Oct 20 , 510 (581-606).

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Pravetoni M et al. Behavioral characterization of mice lacking GIRK/Kir3 channel subunits.
Genes Brain Behav., 2008 Jul , 7 (523-31).

109

Owsianowski E et al. Negative regulation of apoptosis in yeast.
Biochim. Biophys. Acta, 2008 Jul , 1783 (1303-10).

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Cruz HG et al. Absence and rescue of morphine withdrawal in GIRK/Kir3 knock-out mice.
J. Neurosci., 2008 Apr 9 , 28 (4069-77).

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Inanobe A et al. Structural diversity in the cytoplasmic region of G protein-gated inward rectifier K+ channels.
Channels (Austin), 2007 Jan-Feb , 1 (39-45).

119

Papp M et al. [Relevance of serologic studies in inflammatory bowel diseases]
, 2007 May 13 , 148 (887-96).

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Papadakis KA et al. Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations.
Inflamm. Bowel Dis., 2007 May , 13 (524-30).

128

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Kawano T et al. Interaction of Galphaq and Kir3, G protein-coupled inwardly rectifying potassium channels.
Mol. Pharmacol., 2007 Apr , 71 (1179-84).

134

Steinecker B et al. The GIRK1 brain variant GIRK1d and its functional impact on heteromultimeric GIRK channels.
J. Recept. Signal Transduct. Res., 2007 , 27 (369-82).

136

Grabe M et al. K+ channel selectivity depends on kinetic as well as thermodynamic factors.
Proc. Natl. Acad. Sci. U.S.A., 2006 Sep 26 , 103 (14361-6).

137

Bichet D et al. Electrostatic interactions in the channel cavity as an important determinant of potassium channel selectivity.
Proc. Natl. Acad. Sci. U.S.A., 2006 Sep 26 , 103 (14355-60).

142

Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by the antidepressant paroxetine.
J. Pharmacol. Sci., 2006 Nov , 102 (278-87).

144

Stasko MR et al. Hypothermic responses to 8-OH-DPAT in the Ts65Dn mouse model of Down syndrome.
Neuroreport, 2006 May 29 , 17 (837-41).

145

Thomas AM et al. Differential phosphoinositide binding to components of the G protein-gated K+ channel.
J. Membr. Biol., 2006 May , 211 (43-53).

146

Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil.
Neuropsychopharmacology, 2006 Mar , 31 (516-24).

150

Hüttmann K et al. Molecular and functional properties of neurons in the human lateral amygdala.
Mol. Cell. Neurosci., 2006 Feb , 31 (210-7).

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Kanjhan R et al. Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner.
J. Pharmacol. Exp. Ther., 2005 Sep , 314 (1353-61).

160

Cucullo L et al. Very low intensity alternating current decreases cell proliferation.
Glia, 2005 Jul , 51 (65-72).

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Koyrakh L et al. Molecular and cellular diversity of neuronal G-protein-gated potassium channels.
J. Neurosci., 2005 Dec 7 , 25 (11468-78).

166

Koike-Tani M et al. Signal transduction pathway for the substance P-induced inhibition of rat Kir3 (GIRK) channel.
J. Physiol. (Lond.), 2005 Apr 15 , 564 (489-500).

172

Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Neuropsychopharmacology, 2004 Oct , 29 (1841-51).

174

Pil J et al. Synthesis and electrophysiological characterization of cyclic morphiceptin analogues.
Biochem. Pharmacol., 2004 May 15 , 67 (1887-95).

175

Bichet D et al. Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity.
Proc. Natl. Acad. Sci. U.S.A., 2004 Mar 30 , 101 (4441-6).

180

Kurachi Y et al. Cell signal control of the G protein-gated potassium channel and its subcellular localization.
J. Physiol. (Lond.), 2004 Jan 15 , 554 (285-94).

185

Chen L et al. Inwardly rectifying potassium channels in rat retinal ganglion cells.
Eur. J. Neurosci., 2004 Aug , 20 (956-64).

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Zhao Q et al. Interaction of G protein beta subunit with inward rectifier K(+) channel Kir3.
Mol. Pharmacol., 2003 Nov , 64 (1085-91).

189

Drenhaus U et al. On the development of the stratification of the inner plexiform layer in the chick retina.
J. Comp. Neurol., 2003 May 19 , 460 (1-12).

190

Morgan AD et al. Decreased cocaine self-administration in Kir3 potassium channel subunit knockout mice.
Neuropsychopharmacology, 2003 May , 28 (932-8).

191

Gerstin KM et al. Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentration.
Anesth. Analg., 2003 May , 96 (1345-9, table of contents).

193

Pil J et al. Serine 329 of the mu-opioid receptor interacts differently with agonists.
J. Pharmacol. Exp. Ther., 2003 Mar , 304 (924-30).

194

Kobayashi T et al. Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac).
Br. J. Pharmacol., 2003 Mar , 138 (1119-28).

196

Blednov YA et al. A pervasive mechanism for analgesia: activation of GIRK2 channels.
Proc. Natl. Acad. Sci. U.S.A., 2003 Jan 7 , 100 (277-82).

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Thiery E et al. Chromosome 21 KIR channels in brain development.
J. Neural Transm. Suppl., 2003 , (105-15).

206

Suda S et al. Potassium channel mRNAs with AU-rich elements and brain-specific expression.
Biochem. Biophys. Res. Commun., 2002 Mar 15 , 291 (1265-71).

210

Harkins AB et al. Cell death in weaver mouse cerebellum.
Cerebellum, 2002 Jul , 1 (201-6).

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Kobayashi T et al. Functional characterization of an endogenous Xenopus oocyte adenosine receptor.
Br. J. Pharmacol., 2002 Jan , 135 (313-22).

212

Wickman K et al. Structural characterization of the mouse Girk genes.
Gene, 2002 Feb 6 , 284 (241-50).

214

Brochiero E et al. Cloning of rabbit Kir6.1, SUR2A, and SUR2B: possible candidates for a renal K(ATP) channel.
Am. J. Physiol. Renal Physiol., 2002 Feb , 282 (F289-300).

215

Blednov YA et al. Hyperactivity and dopamine D1 receptor activation in mice lacking girk2 channels.
Psychopharmacology (Berl.), 2002 Feb , 159 (370-8).

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Wickenden AD Potassium channels as anti-epileptic drug targets.
Neuropharmacology, 2002 Dec , 43 (1055-60).

221

Leaney JL et al. A novel strategy to engineer functional fluorescent inhibitory G-protein alpha subunits.
J. Biol. Chem., 2002 Aug 9 , 277 (28803-9).

223

Ozaki M et al. Degeneration of pontine mossy fibres during cerebellar development in weaver mutant mice.
Eur. J. Neurosci., 2002 Aug , 16 (565-74).

225

Blednov YA et al. GIRK2 deficient mice. Evidence for hyperactivity and reduced anxiety.
Physiol. Behav., 2001 Sep 1-15 , 74 (109-17).

226

Yi BA et al. Controlling potassium channel activities: Interplay between the membrane and intracellular factors.
Proc. Natl. Acad. Sci. U.S.A., 2001 Sep 25 , 98 (11016-23).

228

Mascia MP et al. Does acetaldehyde mediate ethanol action in the central nervous system?
Alcohol. Clin. Exp. Res., 2001 Nov , 25 (1570-5).

230

Zhou W et al. Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels.
Proc. Natl. Acad. Sci. U.S.A., 2001 May 22 , 98 (6482-7).

231

Salvador C et al. Functional properties of a truncated recombinant GIRK5 potassium channel.
Biochim. Biophys. Acta, 2001 May 2 , 1512 (135-47).

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Medina I et al. A switch mechanism for G beta gamma activation of I(KACh).
J. Biol. Chem., 2000 Sep 22 , 275 (29709-16).

242

Mark MD et al. G-protein mediated gating of inward-rectifier K+ channels.
Eur. J. Biochem., 2000 Oct , 267 (5830-6).

244

Xu H et al. Molecular determinants for the distinct pH sensitivity of Kir1.1 and Kir4.1 channels.
Am. J. Physiol., Cell Physiol., 2000 Nov , 279 (C1464-71).

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Hou P et al. Impermeability of the GIRK2 weaver channel to divalent cations.
Am. J. Physiol., Cell Physiol., 2000 May , 278 (C1038-46).

253

Bradley KK et al. Kir3.1/3.2 encodes an I(KACh)-like current in gastrointestinal myocytes.
Am. J. Physiol. Gastrointest. Liver Physiol., 2000 Feb , 278 (G289-96).

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Wickman K et al. Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4.
J. Neurosci., 2000 Aug 1 , 20 (5608-15).

257

Liesi P et al. Involvement of GIRK2 in postnatal development of the weaver cerebellum.
J. Neurosci. Res., 2000 Apr 15 , 60 (164-73).

258

Harkins AB et al. Evidence of elevated intracellular calcium levels in weaver homozygote mice.
J. Physiol. (Lond.), 2000 Apr 15 , 524 Pt 2 (447-55).

260

Jensen P et al. Rescue of cerebellar granule cells from death in weaver NR1 double mutants.
J. Neurosci., 1999 Sep 15 , 19 (7991-8).

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Yoon HJ et al. Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events.
Proc. Natl. Acad. Sci. U.S.A., 1999 Nov 9 , 96 (13208-13).

265

Ho IH et al. Molecular mechanism for sodium-dependent activation of G protein-gated K+ channels.
J. Physiol. (Lond.), 1999 Nov 1 , 520 Pt 3 (645-51).

268

Ho IH et al. Molecular determinants for sodium-dependent activation of G protein-gated K+ channels.
J. Biol. Chem., 1999 Mar 26 , 274 (8639-48).

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Fernández-Fernández JM et al. Selective activation of heterologously expressed G protein-gated K+ channels by M2 muscarinic receptors in rat sympathetic neurones.
J. Physiol. (Lond.), 1999 Mar 15 , 515 ( Pt 3) (631-7).

275

Ulens C et al. The dual modulation of GIRK1/GIRK2 channels by opioid receptor ligands.
Eur. J. Pharmacol., 1999 Dec 3 , 385 (239-45).

277

Lewohl JM et al. G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action.
Nat. Neurosci., 1999 Dec , 2 (1084-90).

278

Kobayashi T et al. Ethanol opens G-protein-activated inwardly rectifying K+ channels.
Nat. Neurosci., 1999 Dec , 2 (1091-7).

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283

Womack M et al. Elevated intracellular calcium levels in cerebellar granule neurons of weaver mice.
Neuroreport, 1998 Oct 26 , 9 (3391-5).

285

287

Oliver D et al. Interaction of permeant and blocking ions in cloned inward-rectifier K+ channels.
Biophys. J., 1998 May , 74 (2318-26).

293

Kuzhikandathil EV et al. Human dopamine D3 and D2L receptors couple to inward rectifier potassium channels in mammalian cell lines.
Mol. Cell. Neurosci., 1998 Dec , 12 (390-402).

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Woodward R et al. Molecular determinants for assembly of G-protein-activated inwardly rectifying K+ channels.
J. Biol. Chem., 1997 Apr 18 , 272 (10823-30).

313

Bjerregaard A et al. Weaver mutant mouse cerebellar granule cells respond normally to chronic depolarization.
Int. J. Dev. Neurosci., 1997 Apr , 15 (155-62).

314

Wischmeyer E et al. Subunit interactions in the assembly of neuronal Kir3.0 inwardly rectifying K+ channels.
Mol. Cell. Neurosci., 1997 , 9 (194-206).

315

Karschin C et al. Ontogeny of gene expression of Kir channel subunits in the rat.
Mol. Cell. Neurosci., 1997 , 10 (131-48).

317

Surmeier DJ et al. The weaver mutation of GIRK2 results in a loss of inwardly rectifying K+ current in cerebellar granule cells.
Proc. Natl. Acad. Sci. U.S.A., 1996 Oct 1 , 93 (11191-5).

321

Navarro B et al. Nonselective and G betagamma-insensitive weaver K+ channels.
Science, 1996 Jun 28 , 272 (1950-3).

323

328

Nelson CS et al. Melatonin receptors activate heteromeric G-protein coupled Kir3 channels.
Neuroreport, 1996 Feb 29 , 7 (717-20).

330

Silverman SK et al. A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation.
Proc. Natl. Acad. Sci. U.S.A., 1996 Dec 24 , 93 (15429-34).

331

Cohen NA et al. Inhibition of an inward rectifier potassium channel (Kir2.3) by G-protein betagamma subunits.
J. Biol. Chem., 1996 Dec 13 , 271 (32301-5).

333

Dixon AK et al. Distribution of mRNA encoding the inwardly rectifying K+ channel, BIR1 in rat tissues.
FEBS Lett., 1995 Oct 23 , 374 (135-40).

335

Doi T et al. Subunit-specific inhibition of inward-rectifier K+ channels by quinidine.
FEBS Lett., 1995 Nov 20 , 375 (193-6).

343

Lesage F et al. Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels.
J. Biol. Chem., 1995 Dec 1 , 270 (28660-7).

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Glowatzki E et al. Subunit-dependent assembly of inward-rectifier K+ channels.
Proc. Biol. Sci., 1995 Aug 22 , 261 (251-61).