Channelpedia

Kv1.3 Channel

744 automatically matched literature references

1

Wan LS et al. Three Minor Diterpenoids with Three Carbon Skeletons from Euphorbia peplus.
Org. Lett., 2016 May 6 , 18 (2166-9).

2

Velez P et al. Ubiquitin ligase Nedd4-2 modulates Kv1.3 current amplitude and ion channel protein targeting.
J. Neurophysiol., 2016 May 4 , (jn.00874.2015).

13

Doczi MA et al. Developmental expression of Kv1 voltage-gated potassium channels in the avian hypothalamus.
Neurosci. Lett., 2016 Feb 1 , 616 (182-188).

14

Kan XH et al. Kv1.3 potassium channel mediates macrophage migration in atherosclerosis by regulating ERK activity.
Arch. Biochem. Biophys., 2016 Feb 1 , 591 (150-6).

16

Laskowski M et al. What do we not know about mitochondrial potassium channels?
Biochim. Biophys. Acta, 2016 Aug , 1857 (1247-57).

21

Chen R et al. Peptidomimetic Star Polymers for Targeting Biological Ion Channels.
PLoS ONE, 2016 , 11 (e0152169).

22

23

Pérez-Verdaguer M et al. Caveolin interaction governs Kv1.3 lipid raft targeting.
Sci Rep, 2016 , 6 (22453).

26

Wang X et al. A single-point mutation enhances dual functionality of a scorpion toxin.
Comp. Biochem. Physiol. C Toxicol. Pharmacol., 2015 Sep 7 , 179 (72-78).

29

Xu H et al. Characterization of the direct interaction between KcsA-Kv1.3 and its inhibitors.
Biochim. Biophys. Acta, 2015 Oct , 1848 (1974-80).

31

32

33

36

39

Leanza L et al. Targeting a mitochondrial potassium channel to fight cancer.
Cell Calcium, 2015 Jul , 58 (131-8).

40

Rubiolo JA et al. Potassium currents inhibition by gambierol analogs prevents human T lymphocyte activation.
Arch. Toxicol., 2015 Jul , 89 (1119-34).

46

Zhao R et al. Designer and natural peptide toxin blockers of the KcsA potassium channel identified by phage display.
Proc. Natl. Acad. Sci. U.S.A., 2015 Dec 15 , 112 (E7013-21).

53

Hosseinzadeh Z et al. Up-regulation of Kv1.3 channels by janus kinase 2.
J. Membr. Biol., 2015 Apr , 248 (309-17).

56

Meredith FL et al. Kv1 channels and neural processing in vestibular calyx afferents.
Front Syst Neurosci, 2015 , 9 (85).

59

Rangaraju S et al. Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease.
J. Alzheimers Dis., 2015 , 44 (797-808).

63

Bartok A et al. Margatoxin is a non-selective inhibitor of human Kv1.3 K(+) channels.
Toxicon, 2014 Sep , 87 (6-16).

65

Carrisoza-Gaytán R et al. Differential expression of the Kv1 voltage-gated potassium channel family in the rat nephron.
J. Mol. Histol., 2014 Oct , 45 (583-97).

68

Delaney E et al. Determinants of pore folding in potassium channel biogenesis.
Proc. Natl. Acad. Sci. U.S.A., 2014 Mar 25 , 111 (4620-5).

69

Panyi G et al. Ion channels and anti-cancer immunity.
Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2014 Mar 19 , 369 (20130106).

71

Coleman N et al. New Positive KCa Channel Gating Modulators with Selectivity for KCa3.1.
Mol. Pharmacol., 2014 Jun 23 , ().

83

Ahmed M et al. Down-regulation of K⁺ channels by human parvovirus B19 capsid protein VP1.
Biochem. Biophys. Res. Commun., 2014 Aug 8 , 450 (1396-401).

87

90

Peng Y et al. Blockade of Kv1.3 channels ameliorates radiation-induced brain injury.
Neuro-oncology, 2014 Apr , 16 (528-39).

91

Zhao N et al. Acacetin blocks kv1.3 channels and inhibits human T cell activation.
Cell. Physiol. Biochem., 2014 , 34 (1359-72).

93

95

Wang W et al. Effects of voltage-gated K+ channel on cell proliferation in multiple myeloma.
ScientificWorldJournal, 2014 , 2014 (785140).

96

Almilaji A et al. Regulation of the voltage gated K channel Kv1.3 by recombinant human klotho protein.
Kidney Blood Press. Res., 2014 , 39 (609-22).

101

Szilágyi O et al. The role of PSD-95 in the rearrangement of Kv1.3 channels to the immunological synapse.
Pflugers Arch., 2013 Sep , 465 (1341-53).

104

Combs DJ et al. Tuning voltage-gated channel activity and cellular excitability with a sphingomyelinase.
J. Gen. Physiol., 2013 Oct , 142 (367-380).

107

Duque A et al. Expression of Kv1.3 potassium channels regulates density of cortical interneurons.
Dev Neurobiol, 2013 Nov , 73 (841-55).

109

Tucker K et al. Glucose sensitivity of mouse olfactory bulb neurons is conveyed by a voltage-gated potassium channel.
J. Physiol. (Lond.), 2013 May 15 , 591 (2541-61).

113

Weingarth M et al. Structural determinants of specific lipid binding to potassium channels.
J. Am. Chem. Soc., 2013 Mar 13 , 135 (3983-8).

116

Zhang L et al. CMYA5: a new potential substrate of Kcna3 in human heart.
Acta Biochim. Biophys. Sin. (Shanghai), 2013 Mar , 45 (236-8).

121

Upadhyay SK et al. Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance.
Proc. Natl. Acad. Sci. U.S.A., 2013 Jun 11 , 110 (E2239-48).

124

Hilder TA et al. Designing a C84 fullerene as a specific voltage-gated sodium channel blocker.
Nanoscale Res Lett, 2013 Jul 16 , 8 (323).

127

Somodi S et al. Analysis of the K+ current in human CD4+ T lymphocytes in hypercholesterolemic state.
Cell. Immunol., 2013 Jan , 281 (20-6).

130

Yamamoto Y et al. Amiodarone inhibits tissue factor expression in monocytic THP-1 cells.
Eur. J. Pharmacol., 2013 Feb 15 , 701 (14-9).

131

Kazama I et al. Benidipine persistently inhibits delayed rectifier K(+)-channel currents in murine thymocytes.
Immunopharmacol Immunotoxicol, 2013 Feb , 35 (28-33).

138

Nguyen W Novel Kv1.3 blockers for immunosuppression: W02012155199.
Expert Opin Ther Pat, 2013 Aug 23 , ().

140

Gilhar A et al. Blocking potassium channels (Kv1.3): a new treatment option for alopecia areata?
J. Invest. Dermatol., 2013 Aug , 133 (2088-91).

144

Johnson MC et al. Odor enrichment sculpts the abundance of olfactory bulb mitral cells.
Neurosci. Lett., 2013 Apr 29 , 541 (173-8).

147

Leanza L et al. Intracellular ion channels and cancer.
Front Physiol, 2013 , 4 (227).

178

Chimote AA et al. Disruption of kv1.3 channel forward vesicular trafficking by hypoxia in human T lymphocytes.
J. Biol. Chem., 2012 Jan 13 , 287 (2055-67).

181

Wang LH et al. Rituximab inhibits Kv1.3 channels in human B lymphoma cells via activation of FcγRIIB receptors.
Biochim. Biophys. Acta, 2012 Feb , 1823 (505-13).

183

Nguyen W et al. Structure-activity relationship exploration of Kv1.3 blockers based on diphenoxylate.
Bioorg. Med. Chem. Lett., 2012 Dec 1 , 22 (7106-9).

186

187

Tucker K et al. Diet-induced obesity resistance of Kv1.3-/- mice is olfactory bulb dependent.
J. Neuroendocrinol., 2012 Aug , 24 (1087-95).

189

200

Leanza L et al. Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels.
Curr. Med. Chem., 2012 , 19 (5394-404).

202

Beeton C et al. Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases.
Inflamm Allergy Drug Targets, 2011 Oct 1 , 10 (313-21).

203

Doczi MA et al. A C-terminal PDZ binding domain modulates the function and localization of Kv1.3 channels.
Exp. Cell Res., 2011 Oct 1 , 317 (2333-41).

208

Ramirez-Navarro A et al. Kv1.3 channels regulate synaptic transmission in the nucleus of solitary tract.
J. Neurophysiol., 2011 Jun , 105 (2772-80).

209

Gao B et al. Molecular divergence of two orthologous scorpion toxins affecting potassium channels.
Comp. Biochem. Physiol., Part A Mol. Integr. Physiol., 2011 Jul , 159 (313-21).

212

213

Gilhar A et al. The beneficial effect of blocking Kv1.3 in the psoriasiform SCID mouse model.
J. Invest. Dermatol., 2011 Jan , 131 (118-24).

219

Zhu S et al. Molecular diversity and functional evolution of scorpion potassium channel toxins.
Mol. Cell Proteomics, 2011 Feb , 10 (M110.002832).

220

Chen R et al. Modeling the binding of three toxins to the voltage-gated potassium channel (Kv1.3).
Biophys. J., 2011 Dec 7 , 101 (2652-60).

222

223

Novakovic A et al. Different K+ channels are involved in relaxation of arterial and venous graft induced by nicorandil.
J. Cardiovasc. Pharmacol., 2011 Dec , 58 (602-8).

225

231

Gulbins E et al. Role of Kv1.3 mitochondrial potassium channel in apoptotic signalling in lymphocytes.
Biochim. Biophys. Acta, 2010 Jun-Jul , 1797 (1251-9).

235

Choi BH et al. Kv1.3: a potential pharmacological target for diabetes.
Acta Pharmacol. Sin., 2010 Sep , 31 (1031-5).

241

Szabò I et al. Contribution of voltage-gated potassium channels to the regulation of apoptosis.
FEBS Lett., 2010 May 17 , 584 (2049-56).

242

Cheng Y et al. Interaction of mitochondrial potassium channels with the permeability transition pore.
FEBS Lett., 2010 May 17 , 584 (2005-12).

244

Rangaraju S et al. Potassium channel modulation by a toxin domain in matrix metalloprotease 23.
J. Biol. Chem., 2010 Mar 19 , 285 (9124-36).

246

Tu LW et al. A folding zone in the ribosomal exit tunnel for Kv1.3 helix formation.
J. Mol. Biol., 2010 Mar 12 , 396 (1346-60).

249

Emerson M Kv1.3: the perfect opening of the platelet voltage gate.
J. Physiol. (Lond.), 2010 Jun 1 , 588 (1809).

250

Jackson WF KV1.3: a new therapeutic target to control vascular smooth muscle cell proliferation.
Arterioscler. Thromb. Vasc. Biol., 2010 Jun , 30 (1073-4).

253

Carrisoza-Gaytán R et al. Potassium secretion by voltage-gated potassium channel Kv1.3 in the rat kidney.
Am. J. Physiol. Renal Physiol., 2010 Jul , 299 (F255-64).

254

256

Pang B et al. TNF-alpha inhibits the CD3-mediated upregulation of voltage-gated K+ channel (Kv1.3) in human T cells.
Biochem. Biophys. Res. Commun., 2010 Jan 1 , 391 (909-14).

262

Wulff H Spiro azepane-oxazolidinones as Kv1.3 potassium channel blockers: WO2010066840.
Expert Opin Ther Pat, 2010 Dec , 20 (1759-65).

264

Gazula VR et al. Localization of Kv1.3 channels in presynaptic terminals of brainstem auditory neurons.
J. Comp. Neurol., 2010 Aug 15 , 518 (3205-20).

267

269

Bielanska J et al. Voltage-dependent potassium channels Kv1.3 and Kv1.5 in human fetus.
Cell. Physiol. Biochem., 2010 , 26 (219-26).

271

Nguyen W et al. Use of Kv1.3 blockers for inflammatory skin conditions.
Curr. Med. Chem., 2010 , 17 (2882-96).

274

Guthoff M et al. Effect of genetic variation in Kv1.3 on olfactory function.
Diabetes Metab. Res. Rev., 2009 Sep , 25 (523-7).

275

Cahalan MD et al. The functional network of ion channels in T lymphocytes.
Immunol. Rev., 2009 Sep , 231 (59-87).

277

278

Zsiros E et al. Developmental switch of the expression of ion channels in human dendritic cells.
J. Immunol., 2009 Oct 1 , 183 (4483-92).

282

Matsushita Y et al. Inhibition of Kv1.3 potassium current by phosphoinositides and stromal-derived factor-1alpha in Jurkat T cells.
Am. J. Physiol., Cell Physiol., 2009 May , 296 (C1079-85).

283

Nekrasova OV et al. Recombinant Kv channels at the membrane of Escherichia coli bind specifically agitoxin2.
J Neuroimmune Pharmacol, 2009 Mar , 4 (83-91).

284

Gendelman HE et al. Monocyte chemotactic protein-1 regulates voltage-gated K+ channels and macrophage transmigration.
J Neuroimmune Pharmacol, 2009 Mar , 4 (47-59).

286

287

291

Winklmeier A et al. Crystallization and preliminary X-ray diffraction studies of the tetramerization domain derived from the human potassium channel Kv1.3.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 2009 Jul 1 , 65 (688-91).

294

296

Szewczyk A et al. Mitochondrial potassium channels.
IUBMB Life, 2009 Feb , 61 (134-43).

297

Li MW et al. [Effects of telmisartan on voltage-gated Kv1.3 and Kv1.5 potassium channels expressed in Xenopus oocytes]
Zhonghua Xin Xue Guan Bing Za Zhi, 2009 Feb , 37 (165-8).

298

Takacs Z et al. A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library.
Proc. Natl. Acad. Sci. U.S.A., 2009 Dec 29 , 106 (22211-6).

299

Valencia-Cruz G et al. K(bg) and Kv1.3 channels mediate potassium efflux in the early phase of apoptosis in Jurkat T lymphocytes.
Am. J. Physiol., Cell Physiol., 2009 Dec , 297 (C1544-53).

300

Bielanska J et al. Voltage-dependent potassium channels Kv1.3 and Kv1.5 in human cancer.
Curr Cancer Drug Targets, 2009 Dec , 9 (904-14).

304

Rangaraju S et al. Kv1.3 potassium channels as a therapeutic target in multiple sclerosis.
Expert Opin. Ther. Targets, 2009 Aug , 13 (909-24).

305

Pegoraro S et al. Inhibitors of potassium channels KV1.3 and IK-1 as immunosuppressants.
Bioorg. Med. Chem. Lett., 2009 Apr 15 , 19 (2299-304).

307

Pennington MW et al. Engineering a stable and selective peptide blocker of the Kv1.3 channel in T lymphocytes.
Mol. Pharmacol., 2009 Apr , 75 (762-73).

312

Xuan NT et al. Ca2+-dependent functions in peptidoglycan-stimulated mouse dendritic cells.
Cell. Physiol. Biochem., 2009 , 24 (167-76).

313

Bednarczyk P Potassium channels in brain mitochondria.
Acta Biochim. Pol., 2009 , 56 (385-92).

315

Szabò I et al. Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes.
Proc. Natl. Acad. Sci. U.S.A., 2008 Sep 30 , 105 (14861-6).

316

Matsushita Y et al. Molecular mechanisms for Kv1.3 potassium channel current inhibition by CD3/CD28 stimulation in Jurkat T cells.
Biochem. Biophys. Res. Commun., 2008 Sep 12 , 374 (152-7).

317

Somodi S et al. Effects of changes in extracellular pH and potassium concentration on Kv1.3 inactivation.
Eur. Biophys. J., 2008 Sep , 37 (1145-56).

318

Pottosin II et al. TRESK-like potassium channels in leukemic T cells.
Pflugers Arch., 2008 Sep , 456 (1037-48).

320

Doczi MA et al. Kv1.3 channels in postganglionic sympathetic neurons: expression, function, and modulation.
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2008 Sep , 295 (R733-40).

324

Abbas N et al. A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes.
Biochem. Biophys. Res. Commun., 2008 Nov 21 , 376 (525-30).

326

Matzner N et al. Ion channels modulating mouse dendritic cell functions.
J. Immunol., 2008 Nov 15 , 181 (6803-9).

329

Estes DJ et al. High-throughput profiling of ion channel activity in primary human lymphocytes.
Anal. Chem., 2008 May 15 , 80 (3728-35).

330

Millar ID et al. Kv1 and Kir2 potassium channels are expressed in rat brain endothelial cells.
Pflugers Arch., 2008 May , 456 (379-91).

331

Villalonga N et al. Cell cycle-dependent expression of Kv1.5 is involved in myoblast proliferation.
Biochim. Biophys. Acta, 2008 May , 1783 (728-36).

334

Vicente R et al. Kv1.5 association modifies Kv1.3 traffic and membrane localization.
J. Biol. Chem., 2008 Mar 28 , 283 (8756-64).

335

Cianci J et al. Synthesis and biological evaluation of chalcones as inhibitors of the voltage-gated potassium channel Kv1.3.
Bioorg. Med. Chem. Lett., 2008 Mar 15 , 18 (2055-61).

336

337

338

Schneider R et al. Solid-state NMR spectroscopy applied to a chimeric potassium channel in lipid bilayers.
J. Am. Chem. Soc., 2008 Jun 11 , 130 (7427-35).

339

Ader C et al. A structural link between inactivation and block of a K+ channel.
Nat. Struct. Mol. Biol., 2008 Jun , 15 (605-12).

345

Salom JB et al. Role of K+ and Ca2+ fluxes in the cerebroarterial vasoactive effects of sildenafil.
Eur. J. Pharmacol., 2008 Feb 26 , 581 (138-47).

346

Petroff EY et al. Acid-sensing ion channels interact with and inhibit BK K+ channels.
Proc. Natl. Acad. Sci. U.S.A., 2008 Feb 26 , 105 (3140-4).

347

Yankelson L et al. Cell therapy for modification of the myocardial electrophysiological substrate.
Circulation, 2008 Feb 12 , 117 (720-31).

350

Martínez-Mármol R et al. Multiple Kv1.5 targeting to membrane surface microdomains.
J. Cell. Physiol., 2008 Dec , 217 (667-73).

351

Cui JX et al. [Study on the roles of voltaged potassium channels in acute hypoxic pulmonary vasoconstriction]
Nan Fang Yi Ke Da Xue Xue Bao, 2008 Dec , 28 (2200-1).

353

354

Mello de Queiroz F et al. Study of membrane potential in T lymphocytes subpopulations using flow cytometry.
BMC Immunol., 2008 , 9 (63).

357

Mao X et al. Cloning and characterization of BmK86, a novel K+ -channel blocker from scorpion venom.
Biochem. Biophys. Res. Commun., 2007 Sep 7 , 360 (728-34).

359

Guo LF et al. [T-lymphocyte voltage dependent K(+) channel is upregulated in patients with acute coronary syndrome]
Zhonghua Xin Xue Guan Bing Za Zhi, 2007 Sep , 35 (818-21).

365

Ahn HS et al. Calcineurin-independent inhibition of KV1.3 by FK-506 (tacrolimus): a novel pharmacological property.
Am. J. Physiol., Cell Physiol., 2007 May , 292 (C1714-22).

367

368

Buraei Z et al. Roscovitine differentially affects CaV2 and Kv channels by binding to the open state.
Neuropharmacology, 2007 Mar , 52 (883-94).

371

Gill S et al. A cell-based Rb(+)-flux assay of the Kv1.3 potassium channel.
, 2007 Jun , 5 (373-80).

372

373

Tu L et al. Biogenesis of the T1-S1 linker of voltage-gated K+ channels.
Biochemistry, 2007 Jul 10 , 46 (8075-84).

375

Wulff H et al. Targeting effector memory T-cells with Kv1.3 blockers.
, 2007 Jul , 10 (438-45).

376

Villalonga N et al. Kv1.3/Kv1.5 heteromeric channels compromise pharmacological responses in macrophages.
Biochem. Biophys. Res. Commun., 2007 Jan 26 , 352 (913-8).

378

Ahn HS et al. Open channel block of Kv1.3 by rosiglitazone and troglitazone: Kv1.3 as the pharmacological target for rosiglitazone.
Naunyn Schmiedebergs Arch. Pharmacol., 2007 Jan , 374 (305-9).

379

Rivera J et al. The role of Kif5B in axonal localization of Kv1 K(+) channels.
Eur. J. Neurosci., 2007 Jan , 25 (136-46).

380

Ousingsawat J et al. Expression of voltage-gated potassium channels in human and mouse colonic carcinoma.
Clin. Cancer Res., 2007 Feb 1 , 13 (824-31).

384

Nutile-McMenemy N et al. Minocycline decreases in vitro microglial motility, beta1-integrin, and Kv1.3 channel expression.
J. Neurochem., 2007 Dec , 103 (2035-46).

389

393

Decher N et al. Binding site of a novel Kv1.5 blocker: a "foot in the door" against atrial fibrillation.
Mol. Pharmacol., 2006 Oct , 70 (1204-11).

396

Beeton C et al. Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.
Proc. Natl. Acad. Sci. U.S.A., 2006 Nov 14 , 103 (17414-9).

399

Wollmann G et al. Voltage-dependent ion channels in the mouse RPE: comparison with Norrie disease mice.
Vision Res., 2006 Mar , 46 (688-98).

400

Teisseyre A et al. Influence of extracellular pH on the modulatory effect of zinc ions on Kv1.3 potassium channels.
J. Physiol. Pharmacol., 2006 Mar , 57 (131-47).

403

Teisseyre A et al. The inhibitory effect of copper ions on lymphocyte Kv1.3 potassium channels.
J. Physiol. Pharmacol., 2006 Jun , 57 (301-14).

409

411

412

Wang F et al. Structural and functional analysis of natrin, a venom protein that targets various ion channels.
Biochem. Biophys. Res. Commun., 2006 Dec 15 , 351 (443-8).

413

Pannasch U et al. The potassium channels Kv1.5 and Kv1.3 modulate distinct functions of microglia.
Mol. Cell. Neurosci., 2006 Dec , 33 (401-11).

414

Lei XJ et al. [Inhibition of human macrophage-derived foam cell differentiation by blocking Kv1.3 and Kir2.1 channels]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2006 Aug , 31 (493-8).

417

Rossokhin A et al. Interaction of d-tubocurarine with potassium channels: molecular modeling and ligand binding.
Mol. Pharmacol., 2006 Apr , 69 (1356-65).

418

Lawson K et al. Modulation of potassium channels as a therapeutic approach.
Curr. Pharm. Des., 2006 , 12 (459-70).

420

Lange A et al. Two-dimensional solid-state NMR applied to a chimeric potassium channel.
J. Recept. Signal Transduct. Res., 2006 , 26 (379-93).

421

Abdul M et al. Reduced Kv1.3 potassium channel expression in human prostate cancer.
J. Membr. Biol., 2006 , 214 (99-102).

422

Teisseyre A et al. Inhibition of the activity of human lymphocyte Kv1.3 potassium channels by resveratrol.
J. Membr. Biol., 2006 , 214 (123-9).

426

Das P et al. Electrophysiological and behavioral phenotype of insulin receptor defective mice.
Physiol. Behav., 2005 Oct 15 , 86 (287-96).

428

Rivera JF et al. The T1 domain of Kv1.3 mediates intracellular targeting to axons.
Eur. J. Neurosci., 2005 Oct , 22 (1853-62).

430

O'Connell KM et al. Targeting of voltage-gated potassium channel isoforms to distinct cell surface microdomains.
J. Cell. Sci., 2005 May 15 , 118 (2155-66).

431

Yan L et al. Stichodactyla helianthus peptide, a pharmacological tool for studying Kv3.2 channels.
Mol. Pharmacol., 2005 May , 67 (1513-21).

432

Teisseyre A et al. Genistein inhibits the activity of kv1.3 potassium channels in human T lymphocytes.
J. Membr. Biol., 2005 May , 205 (71-9).

433

435

Lu J et al. Secondary structure formation of a transmembrane segment in Kv channels.
Biochemistry, 2005 Jun 14 , 44 (8230-43).

436

Srairi-Abid N et al. A new type of scorpion Na+-channel-toxin-like polypeptide active on K+ channels.
Biochem. J., 2005 Jun 1 , 388 (455-64).

438

Desir GV Kv1.3 potassium channel blockade as an approach to insulin resistance.
Expert Opin. Ther. Targets, 2005 Jun , 9 (571-9).

439

Heusser K et al. Trafficking of potassium channels.
Curr. Opin. Neurobiol., 2005 Jun , 15 (364-9).

440

Krasnowska M et al. [The conductivity of potassium ion channels in lymphocytes T of patients with pollinosis]
Pol. Merkur. Lekarski, 2005 Jun , 18 (617-9).

441

Harvey AJ et al. A three-residue, continuous binding epitope peptidomimetic of ShK toxin as a Kv1.3 inhibitor.
Bioorg. Med. Chem. Lett., 2005 Jul 1 , 15 (3193-6).

442

Bao J et al. Potent Kv1.3 inhibitors from correolide-modification of the C18 position.
Bioorg. Med. Chem. Lett., 2005 Jan 17 , 15 (447-51).

448

Beeton C et al. Potassium channels, memory T cells, and multiple sclerosis.
, 2005 Dec , 11 (550-62).

449

Fordyce CB et al. Microglia Kv1.3 channels contribute to their ability to kill neurons.
J. Neurosci., 2005 Aug 3 , 25 (7139-49).

453

Szabò I et al. A novel potassium channel in lymphocyte mitochondria.
J. Biol. Chem., 2005 Apr 1 , 280 (12790-8).

457

Strauss U et al. Dopamine exerts no acute effects on Kv1.3 in activated encephalitogenic T cells.
Neuroimmunomodulation, 2005 , 12 (45-53).

459

Lang F et al. Cell volume and the regulation of apoptotic cell death.
J. Mol. Recognit., 2004 Sep-Oct , 17 (473-80).

461

Wang W Renal potassium channels: recent developments.
Curr. Opin. Nephrol. Hypertens., 2004 Sep , 13 (549-55).

462

Kosolapov A et al. Structure acquisition of the T1 domain of Kv1.3 during biogenesis.
Neuron, 2004 Oct 14 , 44 (295-307).

464

Somodi S et al. pH-dependent modulation of Kv1.3 inactivation: role of His399.
Am. J. Physiol., Cell Physiol., 2004 Oct , 287 (C1067-76).

466

Kauferstein S et al. Novel conopeptides of the I-superfamily occur in several clades of cone snails.
Toxicon, 2004 Oct , 44 (539-48).

467

468

Visan V et al. Mapping of maurotoxin binding sites on hKv1.2, hKv1.3, and hIKCa1 channels.
Mol. Pharmacol., 2004 Nov , 66 (1103-12).

470

Chandy KG et al. K+ channels as targets for specific immunomodulation.
Trends Pharmacol. Sci., 2004 May , 25 (280-9).

472

Panyi G et al. Ion channels and lymphocyte activation.
Immunol. Lett., 2004 Mar 29 , 92 (55-66).

473

Xu J et al. The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity.
Proc. Natl. Acad. Sci. U.S.A., 2004 Mar 2 , 101 (3112-7).

474

475

Ferber M et al. Identification of a mammalian target of kappaM-conotoxin RIIIK.
Toxicon, 2004 Jun 15 , 43 (915-21).

479

Szabò I et al. Ion channels and membrane rafts in apoptosis.
Pflugers Arch., 2004 Jun , 448 (304-12).

480

Vennekamp J et al. Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators.
Mol. Pharmacol., 2004 Jun , 65 (1364-74).

483

Huys I et al. A subfamily of acidic alpha-K(+) toxins.
J. Biol. Chem., 2004 Jan 23 , 279 (2781-9).

487

Duzhyy DE et al. Cloning and developmental expression of Shaker potassium channels in the cochlea of the chicken.
Brain Res. Mol. Brain Res., 2004 Feb 5 , 121 (70-85).

488

Panyi G et al. Kv1.3 potassium channels are localized in the immunological synapse formed between cytotoxic and target cells.
Proc. Natl. Acad. Sci. U.S.A., 2004 Feb 3 , 101 (1285-90).

489

494

Huys I et al. Structure-function study of a chlorotoxin-chimer and its activity on Kv1.3 channels.
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2004 Apr 15 , 803 (67-73).

495

Escobar LI et al. A voltage-gated K(+) current in renal inner medullary collecting duct cells.
Am. J. Physiol., Cell Physiol., 2004 Apr , 286 (C965-74).

501

Abdul M et al. Activity of potassium channel-blockers in breast cancer.
Anticancer Res., 2003 Jul-Aug , 23 (3347-51).

502

Grunnet M et al. The voltage-gated potassium channel subunit, Kv1.3, is expressed in epithelia.
Biochim. Biophys. Acta, 2003 Sep 22 , 1616 (85-94).

504

Grunnet M et al. KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.
Biophys. J., 2003 Sep , 85 (1525-37).

505

506

Koni PA et al. Compensatory anion currents in Kv1.3 channel-deficient thymocytes.
J. Biol. Chem., 2003 Oct 10 , 278 (39443-51).

507

MacKenzie AB et al. Kv1.3 potassium channels in human alveolar macrophages.
Am. J. Physiol. Lung Cell Mol. Physiol., 2003 Oct , 285 (L862-8).

508

509

Lampert A et al. Effect of dexamethasone on voltage-gated K+ channels in Jurkat T-lymphocytes.
Pflugers Arch., 2003 Nov , 447 (168-74).

510

Huys I et al. Evidence for a function-specific mutation in the neurotoxin, parabutoxin 3.
Eur. J. Neurosci., 2003 May , 17 (1786-92).

512

Miao S et al. Benzamide derivatives as blockers of Kv1.3 ion channel.
Bioorg. Med. Chem. Lett., 2003 Mar 24 , 13 (1161-4).

514

515

516

Hajdu P et al. Cholesterol modifies the gating of Kv1.3 in human T lymphocytes.
Pflugers Arch., 2003 Mar , 445 (674-82).

517

Bock J et al. Ceramide inhibits the potassium channel Kv1.3 by the formation of membrane platforms.
Biochem. Biophys. Res. Commun., 2003 Jun 13 , 305 (890-7).

519

Wulff H et al. The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS.
J. Clin. Invest., 2003 Jun , 111 (1703-13).

520

Preussat K et al. Expression of voltage-gated potassium channels Kv1.3 and Kv1.5 in human gliomas.
Neurosci. Lett., 2003 Jul 31 , 346 (33-6).

521

Rodrigues AR et al. Tityustoxin-K(alpha) blockade of the voltage-gated potassium channel Kv1.3.
Br. J. Pharmacol., 2003 Jul , 139 (1180-6).

522

Kauferstein S et al. A novel conotoxin inhibiting vertebrate voltage-sensitive potassium channels.
Toxicon, 2003 Jul , 42 (43-52).

525

Teisseyre A et al. The voltage- and time-dependent blocking effect of trifluoperazine on T lymphocyte Kv1.3 channels.
Biochem. Pharmacol., 2003 Feb 15 , 65 (551-61).

528

529

Shah K et al. Immunosuppressive effects of a Kv1.3 inhibitor.
Cell. Immunol., 2003 Feb , 221 (100-6).

531

Petersson S et al. Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly.
Eur. J. Neurosci., 2003 Dec , 18 (3231-40).

532

538

Abdul M et al. Voltage-gated potassium ion channels in colon cancer.
Oncol. Rep., 2002 Sep-Oct , 9 (961-4).

539

Zaki A et al. Rapid neuromodulation by cortisol in the rat paraventricular nucleus: an in vitro study.
Br. J. Pharmacol., 2002 Sep , 137 (87-97).

540

Jiang B et al. Endogenous Kv channels in human embryonic kidney (HEK-293) cells.
Mol. Cell. Biochem., 2002 Sep , 238 (69-79).

543

545

Smith GA et al. Functional up-regulation of HERG K+ channels in neoplastic hematopoietic cells.
J. Biol. Chem., 2002 May 24 , 277 (18528-34).

546

Alessandri-Haber N et al. Molecular determinants of emerging excitability in rat embryonic motoneurons.
J. Physiol. (Lond.), 2002 May 15 , 541 (25-39).

548

Jespersen T et al. Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes.
BioTechniques, 2002 Mar , 32 (536-8, 540).

551

Zhou ZH et al. Incomplete inactivation of voltage-dependent K+ channels in human B lymphoma cells.
J. Membr. Biol., 2002 Jul 15 , 188 (97-105).

552

Bock J et al. Actinomycin D-induced apoptosis involves the potassium channel Kv1.3.
Biochem. Biophys. Res. Commun., 2002 Jul 12 , 295 (526-31).

553

Thorne GD et al. Hypoxic vasorelaxation inhibition by organ culture correlates with loss of Kv channels but not Ca(2+) channels.
Am. J. Physiol. Heart Circ. Physiol., 2002 Jul , 283 (H247-53).

556

Mason DE et al. Molecular basis of voltage-dependent potassium currents in porcine granulosa cells.
Mol. Pharmacol., 2002 Jan , 61 (201-13).

560

Gamper N et al. IGF-1 up-regulates K+ channels via PI3-kinase, PDK1 and SGK1.
Pflugers Arch., 2002 Feb , 443 (625-34).

563

Abdul M et al. Expression and activity of potassium ion channels in human prostate cancer.
Cancer Lett., 2002 Dec 1 , 186 (99-105).

564

Kurata HT et al. Amino-terminal determinants of U-type inactivation of voltage-gated K+ channels.
J. Biol. Chem., 2002 Aug 9 , 277 (29045-53).

567

Teisseyre A et al. Inhibition of the activity of T lymphocyte Kv1.3 channels by extracellular zinc.
Biochem. Pharmacol., 2002 Aug 15 , 64 (595-607).

569

571

Petty HR et al. Interactions of integrins with their partner proteins in leukocyte membranes.
Immunol. Res., 2002 , 25 (75-95).

572

Teisseyre A et al. The influence of membrane lipid metabolites on lymphocyte potassium channel activity.
Cell. Mol. Biol. Lett., 2002 , 7 (1095-109).

573

Vianna-Jorge R et al. WIN 17317-3 blocks Ca2+-activated K+ channels and enhances motility of guinea-pig detrusor muscle.
Eur. J. Pharmacol., 2001 Sep 28 , 428 (45-9).

575

577

Fischer BS et al. Capsaicin inhibits Jurkat T-cell activation by blocking calcium entry current I(CRAC).
J. Pharmacol. Exp. Ther., 2001 Oct , 299 (238-46).

578

Lu J et al. Pegylation: a method for assessing topological accessibilities in Kv1.3.
Biochemistry, 2001 Nov 6 , 40 (13288-301).

583

Komarova SV et al. Osteoclast ion channels: potential targets for antiresorptive drugs.
Curr. Pharm. Des., 2001 May , 7 (637-54).

586

Varga Z et al. Multiple binding sites for melatonin on Kv1.3.
Biophys. J., 2001 Mar , 80 (1280-97).

587

Hinck D et al. Gallamine triethiodide selectively blocks voltage-gated potassium channels in Ranvier nodes.
Gen. Physiol. Biophys., 2001 Mar , 20 (83-95).

589

Kuryshev YA et al. KChAP/Kvbeta1.2 interactions and their effects on cardiac Kv channel expression.
Am. J. Physiol., Cell Physiol., 2001 Jul , 281 (C290-9).

593

594

Carlier E et al. Disulfide bridge reorganization induced by proline mutations in maurotoxin.
FEBS Lett., 2001 Feb 2 , 489 (202-7).

595

Lanigan MD et al. Designed peptide analogues of the potassium channel blocker ShK toxin.
Biochemistry, 2001 Dec 25 , 40 (15528-37).

597

Kourrich S et al. Kaliotoxin, a Kv1.1 and Kv1.3 channel blocker, improves associative learning in rats.
Behav. Brain Res., 2001 Apr 8 , 120 (35-46).

600

Khanna R et al. K+ channels and the microglial respiratory burst.
Am. J. Physiol., Cell Physiol., 2001 Apr , 280 (C796-806).

602

Chang MC et al. Regulation of Kv1.3 channels in activated human T lymphocytes by Ca(2+)-dependent pathways.
Cell. Physiol. Biochem., 2001 , 11 (123-34).

604

Schilling T et al. Upregulation of Kv1.3 K(+) channels in microglia deactivated by TGF-beta.
Am. J. Physiol., Cell Physiol., 2000 Oct , 279 (C1123-34).

606

Ouadid-Ahidouch H et al. KV1.1 K(+) channels identification in human breast carcinoma cells: involvement in cell proliferation.
Biochem. Biophys. Res. Commun., 2000 Nov 19 , 278 (272-7).

607

Péter M et al. Blockage of human T lymphocyte Kv1.3 channels by Pi1, a novel class of scorpion toxin.
Biochem. Biophys. Res. Commun., 2000 Nov 11 , 278 (34-7).

608

Kuryshev YA et al. KChAP as a chaperone for specific K(+) channels.
Am. J. Physiol., Cell Physiol., 2000 May , 278 (C931-41).

611

Legros C et al. Generating a high affinity scorpion toxin receptor in KcsA-Kv1.3 chimeric potassium channels.
J. Biol. Chem., 2000 Jun 2 , 275 (16918-24).

612

Lang R et al. KCNA10: a novel ion channel functionally related to both voltage-gated potassium and CNG cation channels.
Am. J. Physiol. Renal Physiol., 2000 Jun , 278 (F1013-21).

614

616

Tu L et al. Transmembrane biogenesis of Kv1.3.
Biochemistry, 2000 Feb 1 , 39 (824-36).

621

Yao X et al. Close association of the N terminus of Kv1.3 with the pore region.
J. Biol. Chem., 2000 Apr 14 , 275 (10859-63).

623

Jacob A et al. Molecular characterization of a voltage-gated potassium channel expressed in rat testis.
Mol. Hum. Reprod., 2000 Apr , 6 (303-13).

625

626

Jensen BS et al. Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels.
Proc. Natl. Acad. Sci. U.S.A., 1999 Sep 14 , 96 (10917-21).

628

Ouadid-Ahidouch H et al. Potassium channels in rat prostate epithelial cells.
FEBS Lett., 1999 Oct 1 , 459 (15-21).

629

Choi JS et al. Mechanism of fluoxetine block of cloned voltage-activated potassium channel Kv1.3.
J. Pharmacol. Exp. Ther., 1999 Oct , 291 (1-6).

630

Pennington MW et al. Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin.
Biochemistry, 1999 Nov 2 , 38 (14549-58).

632

635

McCormack T et al. The effects of Shaker beta-subunits on the human lymphocyte K+ channel Kv1.3.
J. Biol. Chem., 1999 Jul 16 , 274 (20123-6).

637

Segal AS et al. The T0 domain of rabbit KV1.3 regulates steady state channel protein level.
Biochem. Biophys. Res. Commun., 1999 Jan 8 , 254 (54-64).

640

Kiss L et al. Contribution of the selectivity filter to inactivation in potassium channels.
Biophys. J., 1999 Jan , 76 (253-63).

641

643

Kotecha SA et al. A Kv1.5 to Kv1.3 switch in endogenous hippocampal microglia and a role in proliferation.
J. Neurosci., 1999 Dec 15 , 19 (10680-93).

644

645

Mourre C et al. Distribution in rat brain of binding sites of kaliotoxin, a blocker of Kv1.1 and Kv1.3 alpha-subunits.
J. Pharmacol. Exp. Ther., 1999 Dec , 291 (943-52).

646

Coleman SK et al. Subunit composition of Kv1 channels in human CNS.
J. Neurochem., 1999 Aug , 73 (849-58).

648

Tu L et al. Evidence for dimerization of dimers in K+ channel assembly.
Biophys. J., 1999 Apr , 76 (2004-17).

650

Choi JS et al. Staurosporine directly blocks Kv1.3 channels expressed in Chinese hamster ovary cells.
Naunyn Schmiedebergs Arch. Pharmacol., 1999 Apr , 359 (256-61).

659

Péter M et al. Pandinus imperator scorpion venom blocks voltage-gated K+ channels in human lymphocytes.
Biochem. Biophys. Res. Commun., 1998 Jan 26 , 242 (621-5).

662

Kusaka S et al. Serum-induced changes in the physiology of mammalian retinal glial cells: role of lysophosphatidic acid.
J. Physiol. (Lond.), 1998 Jan 15 , 506 ( Pt 2) (445-58).

663

Tudor JE et al. Ionisation behaviour and solution properties of the potassium-channel blocker ShK toxin.
Eur. J. Biochem., 1998 Jan 15 , 251 (133-41).

665

Manabe I et al. Expression of Shaker-type voltage-gated potassium channel genes in the guinea-pig.
Res. Commun. Mol. Pathol. Pharmacol., 1998 Jan , 99 (33-40).

666

667

Kálmán K et al. ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide.
J. Biol. Chem., 1998 Dec 4 , 273 (32697-707).

668

Leicher T et al. Coexpression of the KCNA3B gene product with Kv1.5 leads to a novel A-type potassium channel.
J. Biol. Chem., 1998 Dec 25 , 273 (35095-101).

669

Greffrath W et al. Components of after-hyperpolarization in magnocellular neurones of the rat supraoptic nucleus in vitro.
J. Physiol. (Lond.), 1998 Dec 1 , 513 ( Pt 2) (493-506).

670

Jou I et al. Expression of Kv1.5 K+ channels in activated microglia in vivo.
Glia, 1998 Dec , 24 (408-14).

671

Kupper J Functional expression of GFP-tagged Kv1.3 and Kv1.4 channels in HEK 293 cells.
Eur. J. Neurosci., 1998 Dec , 10 (3908-12).

672

Yao X et al. Characterization of a regulatory region in the N-terminus of rabbit kv1.3.
Biochem. Biophys. Res. Commun., 1998 Aug 19 , 249 (492-8).

673

674

Fadool DA et al. Modulation of olfactory bulb neuron potassium current by tyrosine phosphorylation.
J. Neurosci., 1998 Aug 15 , 18 (6126-37).

681

Bowlby MR et al. Modulation of the Kv1.3 potassium channel by receptor tyrosine kinases.
J. Gen. Physiol., 1997 Nov , 110 (601-10).

683

Orias M et al. Genomic localization of the human gene for KCNA10, a cGMP-activated K channel.
Genomics, 1997 May 15 , 42 (33-7).

684

Chung I et al. Native Kv1.3 channels are upregulated by protein kinase C.
J. Membr. Biol., 1997 Mar 1 , 156 (73-85).

685

686

687

Gulbins E et al. Ceramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine kinases.
Proc. Natl. Acad. Sci. U.S.A., 1997 Jul 8 , 94 (7661-6).

688

Conforti L et al. Selective inhibition of a slow-inactivating voltage-dependent K+ channel in rat PC12 cells by hypoxia.
J. Physiol. (Lond.), 1997 Jul 15 , 502 ( Pt 2) (293-305).

689

Spencer RH et al. Purification, visualization, and biophysical characterization of Kv1.3 tetramers.
J. Biol. Chem., 1997 Jan 24 , 272 (2389-95).

692

Sheng Z et al. Evidence for interaction between transmembrane segments in assembly of Kv1.3.
Biochemistry, 1997 Dec 9 , 36 (15501-13).

693

Cahalan MD et al. Ion channels in the immune system as targets for immunosuppression.
Curr. Opin. Biotechnol., 1997 Dec , 8 (749-56).

694

Kerschbaum HH et al. Ion channels, Ca2+ signaling, and reporter gene expression in antigen-specific mouse T cells.
J. Immunol., 1997 Aug 15 , 159 (1628-38).

695

696

Lipkind GM et al. A model of scorpion toxin binding to voltage-gated K+ channels.
J. Membr. Biol., 1997 Aug 1 , 158 (187-96).

697

Chung I et al. Regulation of native Kv1.3 channels by cAMP-dependent protein phosphorylation.
Am. J. Physiol., 1997 Aug , 273 (C622-33).

699

Holmes TC et al. Tyrosine phosphorylation of the Kv1.3 potassium channel.
J. Neurosci., 1996 Mar 1 , 16 (1581-90).

700

Panyi G et al. Assembly and suppression of endogenous Kv1.3 channels in human T cells.
J. Gen. Physiol., 1996 Mar , 107 (409-20).

704

DeCoursey TE et al. Ion channel expression in PMA-differentiated human THP-1 macrophages.
J. Membr. Biol., 1996 Jul , 152 (141-57).

706

Turrigiano GG et al. Cellular short-term memory from a slow potassium conductance.
J. Neurophysiol., 1996 Feb , 75 (963-6).

707

Levy DI et al. Recovery from C-type inactivation is modulated by extracellular potassium.
Biophys. J., 1996 Feb , 70 (798-805).

708

710

712

Levy DI et al. A voltage-dependent role for K+ in recovery from C-type inactivation.
Biophys. J., 1996 Dec , 71 (3157-66).

714

Tu L et al. Voltage-gated K+ channels contain multiple intersubunit association sites.
J. Biol. Chem., 1996 Aug 2 , 271 (18904-11).

715

Bertoli A et al. Accumulation of long-lasting inactivation in rat brain K(+)-channels.
, 1996 Aug , 110 (401-12).

717

Hahn SJ et al. Inhibition by nystatin of Kv1.3 channels expressed in Chinese hamster ovary cells.
Neuropharmacology, 1996 , 35 (895-901).

718

Klumpp DJ et al. Identification and localization of K+ channels in the mouse retina.
Vis. Neurosci., 1995 Nov-Dec , 12 (1177-90).

720

723

Pennington MW et al. Chemical synthesis and characterization of ShK toxin: a potent potassium channel inhibitor from a sea anemone.
Int. J. Pept. Protein Res., 1995 Nov , 46 (354-8).

728

Duprat F et al. Susceptibility of cloned K+ channels to reactive oxygen species.
Proc. Natl. Acad. Sci. U.S.A., 1995 Dec 5 , 92 (11796-800).

729

Lewis RS et al. Potassium and calcium channels in lymphocytes.
Annu. Rev. Immunol., 1995 , 13 (623-53).

732

736

737

Marom S et al. State-dependent inactivation of the Kv3 potassium channel.
Biophys. J., 1994 Aug , 67 (579-89).

738

740

Cai YC et al. In vivo and in vitro phosphorylation of the T lymphocyte type n (Kv1.3) potassium channel.
J. Biol. Chem., 1993 Nov 5 , 268 (23720-7).

741

Deutsch C et al. Heterologous expression of specific K+ channels in T lymphocytes: functional consequences for volume regulation.
Proc. Natl. Acad. Sci. U.S.A., 1993 Nov 1 , 90 (10036-40).