Channelpedia

Kv7.4 Channel

187 automatically matched literature references

2

Schütze S et al. KCNQ Potassium Channels Modulate Sensitivity of Skin D-hair Mechanoreceptors.
J. Biol. Chem., 2016 Jan 5 , ().

3

Sihn CR et al. Mechanisms of Calmodulin Regulation of Different Isoforms of Kv7.4 K+ Channels.
J. Biol. Chem., 2016 Jan 29 , 291 (2499-509).

4

Stott JB et al. G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity.
Proc. Natl. Acad. Sci. U.S.A., 2015 May 19 , 112 (6497-502).

6

Sedivy V et al. Role of Kv7 channels in responses of the pulmonary circulation to hypoxia.
Am. J. Physiol. Lung Cell Mol. Physiol., 2015 Jan 1 , 308 (L48-57).

8

Lee S et al. Heterogeneity in Kv7 channel function in the cerebral and coronary circulation.
Microcirculation, 2015 Feb , 22 (109-21).

9

Jepps TA et al. Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone.
J. Physiol. (Lond.), 2015 Dec 15 , 593 (5325-40).

10

Wasano K et al. A novel frameshift mutation in KCNQ4 in a family with autosomal recessive non-syndromic hearing loss.
Biochem. Biophys. Res. Commun., 2015 Aug 7 , 463 (582-6).

13

Grigorov A et al. Kv7 potassium channel subunits and M currents in cultured hippocampal interneurons.
Pflugers Arch., 2014 Sep , 466 (1747-58).

14

Brueggemann LI et al. KCNQ (Kv7) potassium channel activators as bronchodilators: combination with a β2-adrenergic agonist enhances relaxation of rat airways.
Am. J. Physiol. Lung Cell Mol. Physiol., 2014 Mar 15 , 306 (L476-86).

15

Jepps TA et al. Vasorelaxant effects of novel Kv7.4 channel enhancers ML213 and NS15370.
Br. J. Pharmacol., 2014 Jun 9 , ().

17

18

Currò D K+ channels as potential targets for the treatment of gastrointestinal motor disorders.
Eur. J. Pharmacol., 2014 Jun 15 , 733 (97-101).

19

Ishikawa K et al. A Japanese family showing high-frequency hearing loss with KCNQ4 and TECTA mutations.
Acta Otolaryngol., 2014 Jun , 134 (557-63).

20

Brueggemann LI et al. Differential protein kinase C-dependent modulation of Kv7.4 and Kv7.5 subunits of vascular Kv7 channels.
J. Biol. Chem., 2014 Jan 24 , 289 (2099-111).

21

Li P et al. The human ether-a-go-go-related gene activator NS1643 enhances epilepsy-associated KCNQ channels.
J. Pharmacol. Exp. Ther., 2014 Dec , 351 (596-604).

22

Chadha PS et al. Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related peptide-induced cerebral reactivity.
Arterioscler. Thromb. Vasc. Biol., 2014 Apr , 34 (887-93).

27

[To the mechanisms of antiarrhythmic action of Allapinine].
Bioorg. Khim., 2013 Jan-Feb , 39 (105-16).

28

Svalø J et al. Bladder contractility is modulated by Kv7 channels in pig detrusor.
Eur. J. Pharmacol., 2013 Sep 5 , 715 (312-20).

30

31

Spitzmaul G et al. Vestibular role of KCNQ4 and KCNQ5 K+ channels revealed by mouse models.
J. Biol. Chem., 2013 Mar 29 , 288 (9334-44).

36

Zavaritskaya O et al. Role of KCNQ channels in skeletal muscle arteries and periadventitial vascular dysfunction.
Hypertension, 2013 Jan , 61 (151-9).

40

Khanamiri S et al. Contribution of Kv7 channels to basal coronary flow and active response to ischemia.
Hypertension, 2013 Dec , 62 (1090-7).

41

Hosseinzadeh Z et al. Downregulation of KCNQ4 by Janus kinase 2.
J. Membr. Biol., 2013 Apr , 246 (335-41).

42

Martelli A et al. Vasorelaxation by hydrogen sulphide involves activation of Kv7 potassium channels.
Pharmacol. Res., 2013 Apr , 70 (27-34).

49

Pattnaik BR et al. Effects of KCNQ channel modulators on the M-type potassium current in primate retinal pigment epithelium.
Am. J. Physiol., Cell Physiol., 2012 Mar , 302 (C821-33).

50

Choveau FS et al. Pore helix-S6 interactions are critical in governing current amplitudes of KCNQ3 K+ channels.
Biophys. J., 2012 Jun 6 , 102 (2499-509).

51

Heidenreich M et al. KCNQ4 K(+) channels tune mechanoreceptors for normal touch sensation in mouse and man.
Nat. Neurosci., 2012 Jan , 15 (138-45).

53

Sliwinska-Kowalska M et al. Contribution of genetic factors to noise-induced hearing loss: A human studies review.
Mutat. Res., 2012 Dec 1 , ().

54

Brinch M et al. Identification of circulating fetal cell markers by microarray analysis.
Prenat. Diagn., 2012 Aug , 32 (742-51).

62

Kristensen LV et al. Kv7 (KCNQ) channel openers induce hypothermia in the mouse.
Neurosci. Lett., 2011 Jan 20 , 488 (178-82).

63

66

Arnett J et al. Autosomal dominant progressive sensorineural hearing loss due to a novel mutation in the KCNQ4 gene.
Arch. Otolaryngol. Head Neck Surg., 2011 Jan , 137 (54-9).

67

Jepps TA et al. Downregulation of Kv7.4 channel activity in primary and secondary hypertension.
Circulation, 2011 Aug 2 , 124 (602-11).

69

de Heer AM et al. Audioprofile-directed successful mutation analysis in a DFNA2/KCNQ4 (p.Leu274His) family.
Ann. Otol. Rhinol. Laryngol., 2011 Apr , 120 (243-8).

71

Liu Z et al. Parallel evolution of KCNQ4 in echolocating bats.
PLoS ONE, 2011 , 6 (e26618).

73

Zhong XZ et al. Participation of KCNQ (Kv7) potassium channels in myogenic control of cerebral arterial diameter.
J. Physiol. (Lond.), 2010 Sep 1 , 588 (3277-93).

75

Kimitsuki T et al. Property of I(K,)(n) in inner hair cells isolated from guinea-pig cochlea.
Hear. Res., 2010 Mar , 261 (57-62).

76

Bal M et al. Ca2+/calmodulin disrupts AKAP79/150 interactions with KCNQ (M-Type) K+ channels.
J. Neurosci., 2010 Feb 10 , 30 (2311-23).

78

Wu T et al. Effect of salicylate on KCNQ4 of the guinea pig outer hair cell.
J. Neurophysiol., 2010 Apr , 103 (1969-77).

85

Jepps TA et al. Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles.
Am. J. Physiol. Gastrointest. Liver Physiol., 2009 Jul , 297 (G107-15).

89

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Mruk K et al. Discovery of a novel activator of KCNQ1-KCNE1 K channel complexes.
PLoS ONE, 2009 , 4 (e4236).

91

Maeda Y et al. Therapeutic regulation of gene expression in the inner ear using RNA interference.
Adv. Otorhinolaryngol., 2009 , 66 (13-36).

92

Roura-Ferrer M et al. Functional implications of KCNE subunit expression for the Kv7.5 (KCNQ5) channel.
Cell. Physiol. Biochem., 2009 , 24 (325-34).

94

Yeung S et al. Bimodal effects of the Kv7 channel activator retigabine on vascular K+ currents.
Br. J. Pharmacol., 2008 Sep , 155 (62-72).

98

Bal M et al. Calmodulin binding to M-type K+ channels assayed by TIRF/FRET in living cells.
J. Physiol. (Lond.), 2008 May 1 , 586 (2307-20).

100

108

Hansen HH et al. Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS.
J. Physiol. (Lond.), 2008 Apr 1 , 586 (1823-32).

109

Hernandez CC et al. Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications.
J. Physiol. (Lond.), 2008 Apr 1 , 586 (1811-21).

110

Maljevic S et al. Nervous system KV7 disorders: breakdown of a subthreshold brake.
J. Physiol. (Lond.), 2008 Apr 1 , 586 (1791-801).

112

Kros CJ How to build an inner hair cell: challenges for regeneration.
Hear. Res., 2007 May , 227 (3-10).

113

Rocha-Sanchez SM et al. Developmental expression of Kcnq4 in vestibular neurons and neurosensory epithelia.
Brain Res., 2007 Mar 30 , 1139 (117-25).

114

Howard RJ et al. Structural insight into KCNQ (Kv7) channel assembly and channelopathy.
Neuron, 2007 Mar 1 , 53 (663-75).

118

120

Kesser BW et al. An in vitro model system to study gene therapy in the human inner ear.
Gene Ther., 2007 Aug , 14 (1121-31).

121

Jensen HS et al. Inactivation as a new regulatory mechanism for neuronal Kv7 channels.
Biophys. J., 2007 Apr 15 , 92 (2747-56).

123

Su CC et al. Studies of the effect of ionomycin on the KCNQ4 channel expressed in Xenopus oocytes.
Biochem. Biophys. Res. Commun., 2006 Sep 15 , 348 (295-300).

124

Hansen HH et al. The KCNQ channel opener retigabine inhibits the activity of mesencephalic dopaminergic systems of the rat.
J. Pharmacol. Exp. Ther., 2006 Sep , 318 (1006-19).

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126

Van Eyken E et al. KCNQ4: a gene for age-related hearing impairment?
Hum. Mutat., 2006 Oct , 27 (1007-16).

127

Bentzen BH et al. The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.
Neuropharmacology, 2006 Nov , 51 (1068-77).

134

Strutz-Seebohm N et al. Functional coassembly of KCNQ4 with KCNE-beta- subunits in Xenopus oocytes.
Cell. Physiol. Biochem., 2006 , 18 (57-66).

137

Schenzer A et al. Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine.
J. Neurosci., 2005 May 18 , 25 (5051-60).

140

Chambard JM et al. Regulation of the voltage-gated potassium channel KCNQ4 in the auditory pathway.
Pflugers Arch., 2005 Apr , 450 (34-44).

143

Gomez-Casati ME et al. Linopirdine blocks alpha9alpha10-containing nicotinic cholinergic receptors of cochlear hair cells.
J. Assoc. Res. Otolaryngol., 2004 Sep , 5 (261-9).

145

Hougaard C et al. Modulation of KCNQ4 channel activity by changes in cell volume.
Biochim. Biophys. Acta, 2004 Jan 28 , 1660 (1-6).

146

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Grunnet M et al. KCNQ1 channels sense small changes in cell volume.
J. Physiol. (Lond.), 2003 Jun 1 , 549 (419-27).

152

Gamper N et al. Subunit-specific modulation of KCNQ potassium channels by Src tyrosine kinase.
J. Neurosci., 2003 Jan 1 , 23 (84-95).

154

Gribkoff VK The therapeutic potential of neuronal KCNQ channel modulators.
Expert Opin. Ther. Targets, 2003 Dec , 7 (737-48).

155

Schrøder RL et al. Voltage-independent KCNQ4 currents induced by (+/-)BMS-204352.
Pflugers Arch., 2003 Aug , 446 (607-16).

156

Cooper EC et al. M-channels: neurological diseases, neuromodulation, and drug development.
Arch. Neurol., 2003 Apr , 60 (496-500).

157

Wangemann P K(+) cycling and its regulation in the cochlea and the vestibular labyrinth.
Audiol. Neurootol., 2002 Jul-Aug , 7 (199-205).

158

Shah MM et al. Molecular correlates of the M-current in cultured rat hippocampal neurons.
J. Physiol. (Lond.), 2002 Oct 1 , 544 (29-37).

159

Stern RE et al. Audiologic evidence for further genetic heterogeneity at DFNA2.
Acta Otolaryngol., 2002 Oct , 122 (730-5).

160

Wang Q et al. [KCNQ4 gene mutations affected a pedigree with autosomal dominant hereditary hearing loss]
Zhonghua Er Bi Yan Hou Ke Za Zhi, 2002 Oct , 37 (343-7).

161

Jespersen T et al. Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes.
BioTechniques, 2002 Mar , 32 (536-8, 540).

162

De Leenheer EM et al. Longitudinal and cross-sectional phenotype analysis in a new, large Dutch DFNA2/KCNQ4 family.
Ann. Otol. Rhinol. Laryngol., 2002 Mar , 111 (267-74).

163

Wangemann P K+ cycling and the endocochlear potential.
Hear. Res., 2002 Mar , 165 (1-9).

165

Boettger T et al. Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter Kcc4.
Nature, 2002 Apr 25 , 416 (874-8).

166

Goldstein JA et al. Further evidence for a third deafness gene within the DFNA2 locus.
Am. J. Med. Genet., 2002 Apr 1 , 108 (304-9).

167

De Leenheer EM et al. DFNA2/KCNQ4 and its manifestations.
Adv. Otorhinolaryngol., 2002 , 61 (41-6).

168

Bom SJ et al. Speech recognition scores related to age and degree of hearing impairment in DFNA2/KCNQ4 and DFNA9/COCH.
Arch. Otolaryngol. Head Neck Surg., 2001 Sep , 127 (1045-8).

169

Korolkova YV et al. An ERG channel inhibitor from the scorpion Buthus eupeus.
J. Biol. Chem., 2001 Mar 30 , 276 (9868-76).

170

Schrøder RL et al. KCNQ4 channel activation by BMS-204352 and retigabine.
Neuropharmacology, 2001 Jun , 40 (888-98).

172

Søgaard R et al. KCNQ4 channels expressed in mammalian cells: functional characteristics and pharmacology.
Am. J. Physiol., Cell Physiol., 2001 Apr , 280 (C859-66).

173

Robbins J KCNQ potassium channels: physiology, pathophysiology, and pharmacology.
Pharmacol. Ther., 2001 Apr , 90 (1-19).

178

Schroeder BC et al. A constitutively open potassium channel formed by KCNQ1 and KCNE3.
Nature, 2000 Jan 13 , 403 (196-9).

179

Hadley JK et al. Differential tetraethylammonium sensitivity of KCNQ1-4 potassium channels.
Br. J. Pharmacol., 2000 Feb , 129 (413-5).

180

Miraglia del Giudice E et al. Benign familial neonatal convulsions (BFNC) resulting from mutation of the KCNQ2 voltage sensor.
Eur. J. Hum. Genet., 2000 Dec , 8 (994-7).

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Marcotti W et al. Developmental expression of the potassium current IK,n contributes to maturation of mouse outer hair cells.
J. Physiol. (Lond.), 1999 Nov 1 , 520 Pt 3 (653-60).

184

Van Hauwe P et al. Deafness linked to DFNA2: one locus but how many genes?
Nat. Genet., 1999 Mar , 21 (263).

187