Channelpedia

Nav1 Channel

613 automatically matched literature references

3

8

Schilling JM et al. Electrophysiology and metabolism of caveolin-3-overexpressing mice.
Basic Res. Cardiol., 2016 May , 111 (28).

10

Gupta B et al. Antinociceptive properties of shikonin: in vitro and in vivo studies.
Can. J. Physiol. Pharmacol., 2016 Mar 6 , (1-9).

14

Chambers C et al. High-Throughput Screening of NaV1.7 Modulators Using a Giga-Seal Automated Patch Clamp Instrument.
Assay Drug Dev Technol, 2016 Mar , 14 (93-108).

19

Zaklyazminskaya E et al. The role of mutations in the SCN5A gene in cardiomyopathies.
Biochim. Biophys. Acta, 2016 Jul , 1863 (1799-805).

20

Sottas V et al. Negative-dominance phenomenon with genetic variants of the cardiac sodium channel Nav1.5.
Biochim. Biophys. Acta, 2016 Jul , 1863 (1791-8).

23

Wang HG et al. A novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias.
J. Mol. Cell. Cardiol., 2016 Jan 19 , 92 (52-62).

30

Han C et al. Sodium channel Nav1.8: Emerging links to human disease.
Neurology, 2016 Feb 2 , 86 (473-83).

41

Frost JM et al. Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain.
J. Med. Chem., 2016 Apr 14 , 59 (3373-91).

45

Kubanek J et al. Ultrasound modulates ion channel currents.
Sci Rep, 2016 , 6 (24170).

49

Wang X et al. Characterization of Specific Roles of Sodium Channel Subtypes in Regional Anesthesia.
Reg Anesth Pain Med, 2015 Sep-Oct , 40 (599-604).

55

Neshatian L et al. Ranolazine inhibits voltage-gated mechanosensitive sodium channels in human colon circular smooth muscle cells.
Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Sep 15 , 309 (G506-12).

57

Dib-Hajj SD et al. NaV1.9: a sodium channel linked to human pain.
Nat. Rev. Neurosci., 2015 Sep , 16 (511-9).

58

Aktas CC et al. In vitro effects of phenytoin and DAPT on MDA-MB-231 breast cancer cells.
Acta Biochim. Biophys. Sin. (Shanghai), 2015 Sep , 47 (680-6).

62

Musa H et al. SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia.
Proc. Natl. Acad. Sci. U.S.A., 2015 Oct 6 , 112 (12528-33).

65

Patel R et al. Ionic Mechanisms of Spinal Neuronal Cold Hypersensitivity in Ciguatera.
Eur. J. Neurosci., 2015 Oct 10 , ().

67

Nicole S et al. Skeletal muscle sodium channelopathies.
Curr. Opin. Neurol., 2015 Oct , 28 (508-514xs).

68

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Liu C et al. Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expression.
J. Biol. Chem., 2015 May 8 , 290 (12048-57).

75

Han Z et al. The effects of A-803467 on cardiac Nav1.5 channels.
Eur. J. Pharmacol., 2015 May 5 , 754 (52-60).

78

Lolignier S et al. The Nav1.9 channel is a key determinant of cold pain sensation and cold allodynia.
Cell Rep, 2015 May 19 , 11 (1067-78).

81

82

Marionneau C et al. Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications.
J. Mol. Cell. Cardiol., 2015 May , 82 (36-47).

87

Woods CG et al. The phenotype of congenital insensitivity to pain due to the NaV1.9 variant p.L811P.
Eur. J. Hum. Genet., 2015 May , 23 (561-3).

88

Stadler T et al. Erythromelalgia mutation Q875E Stabilizes the activated state of sodium channel Nav1.7.
J. Biol. Chem., 2015 Mar 6 , 290 (6316-25).

93

Ossola D et al. Force-controlled patch clamp of beating cardiac cells.
Nano Lett., 2015 Mar 11 , 15 (1743-50).

94

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101

Hoeijmakers JG et al. Painful peripheral neuropathy and sodium channel mutations.
Neurosci. Lett., 2015 Jun 2 , 596 (51-9).

104

Mercier A et al. Nav1.5 channels can reach the plasma membrane through distinct N-glycosylation states.
Biochim. Biophys. Acta, 2015 Jun , 1850 (1215-23).

106

Fukasawa T et al. A case of recurrent encephalopathy with SCN2A missense mutation.
Brain Dev., 2015 Jun , 37 (631-4).

107

Wannous R et al. Suppression of PPARβ, and DHA treatment, inhibit NaV1.5 and NHE-1 pro-invasive activities.
Pflugers Arch., 2015 Jun , 467 (1249-59).

108

Stroemlund LW et al. Gap junctions - guards of excitability.
Biochem. Soc. Trans., 2015 Jun , 43 (508-12).

116

Talbot S et al. Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.
Neuron, 2015 Jul 15 , 87 (341-54).

122

Wang M et al. [Dynamic expressions of Nav1.2 and Nav1.6 in hippocampal CA3 region of epileptic rats].
Zhonghua Yi Xue Za Zhi, 2015 Jan 6 , 95 (61-5).

126

Wagnon JL et al. Convulsive seizures and SUDEP in a mouse model of SCN8A epileptic encephalopathy.
Hum. Mol. Genet., 2015 Jan 15 , 24 (506-15).

127

Saber S et al. Complex genetic background in a large family with Brugada syndrome.
Physiol Rep, 2015 Jan 1 , 3 ().

128

Lynch SM et al. Dibenzazepines and dibenzoxazepines as sodium channel blockers.
Bioorg. Med. Chem. Lett., 2015 Jan 1 , 25 (43-7).

129

Lynch SM et al. N-Aryl azacycles as novel sodium channel blockers.
Bioorg. Med. Chem. Lett., 2015 Jan 1 , 25 (48-52).

134

Sato T et al. Glial reaction in the spinal cord of the degenerating muscle mouse (Scn8a (dmu)).
Neurochem. Res., 2015 Jan , 40 (124-9).

136

Larsen J et al. The phenotypic spectrum of SCN8A encephalopathy.
Neurology, 2015 Feb 3 , 84 (480-9).

140

144

Jabbari J et al. Common and rare variants in SCN10A modulate the risk of atrial fibrillation.
Circ Cardiovasc Genet, 2015 Feb , 8 (64-73).

150

154

Huang X et al. Age-dependent alterations of voltage-gated Na(+) channel isoforms in rat sinoatrial node.
Mech. Ageing Dev., 2015 Dec , 152 (80-90).

155

Szabat M et al. High-content screening identifies a role for Na(+) channels in insulin production.
R Soc Open Sci, 2015 Dec , 2 (150306).

160

Rubinstein M et al. Dissecting the phenotypes of Dravet syndrome by gene deletion.
Brain, 2015 Aug , 138 (2219-33).

163

Potet F et al. Intracellular calcium attenuates late current conducted by mutant human cardiac sodium channels.
Circ Arrhythm Electrophysiol, 2015 Aug , 8 (933-41).

168

Willis BC et al. Protein Assemblies of Sodium and Inward Rectifier Potassium Channels Control Cardiac Excitability and Arrhythmogenesis.
Am. J. Physiol. Heart Circ. Physiol., 2015 Apr 10 , (ajpheart.00176.2015).

170

Cannon SC Channelopathies of skeletal muscle excitability.
Compr Physiol, 2015 Apr , 5 (761-90).

171

James TF et al. The Nav1.2 channel is regulated by GSK3.
Biochim. Biophys. Acta, 2015 Apr , 1850 (832-44).

174

Bugiardini E et al. SCN4A mutation as modifying factor of myotonic dystrophy type 2 phenotype.
Neuromuscul. Disord., 2015 Apr , 25 (301-7).

179

Mahdavi S et al. Mechanism of Ion Permeation in Mammalian Voltage-Gated Sodium Channels.
PLoS ONE, 2015 , 10 (e0133000).

183

Habib AM et al. Sodium channels and pain.
Handb Exp Pharmacol, 2015 , 227 (39-56).

193

Han Z et al. Deletion of PDK1 causes cardiac sodium current reduction in mice.
PLoS ONE, 2015 , 10 (e0122436).

196

199

Wang L et al. De Novo Mutation in the SCN5A Gene Associated with Brugada Syndrome.
Cell. Physiol. Biochem., 2015 , 36 (2250-62).

202

206

Camargos TS et al. The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening.
PLoS ONE, 2015 , 10 (e0128578).

208

Doran C et al. Mouse DRG Cell Line with Properties of Nociceptors.
PLoS ONE, 2015 , 10 (e0128670).

212

Mirams GR et al. Prediction of Thorough QT study results using action potential simulations based on ion channel screens.
J Pharmacol Toxicol Methods, 2014 Nov-Dec , 70 (246-54).

214

215

King GF et al. No gain, no pain: NaV1.7 as an analgesic target.
ACS Chem Neurosci, 2014 Sep 17 , 5 (749-51).

216

Hien YE et al. CK2 accumulation at the axon initial segment depends on sodium channel Nav1.
FEBS Lett., 2014 Sep 17 , 588 (3403-8).

220

Ho GD et al. Discovery of pyrrolo-benzo-1,4-diazines as potent Na(v)1.7 sodium channel blockers.
Bioorg. Med. Chem. Lett., 2014 Sep 1 , 24 (4110-3).

221

222

Bartok A et al. Margatoxin is a non-selective inhibitor of human Kv1.3 K(+) channels.
Toxicon, 2014 Sep , 87 (6-16).

223

Li T et al. Action potential initiation in neocortical inhibitory interneurons.
PLoS Biol., 2014 Sep , 12 (e1001944).

226

Hirofuji S et al. Role of sodium channels in recovery of sciatic nerve-stretch injury in rats.
Muscle Nerve, 2014 Sep , 50 (425-30).

229

232

Devigili G et al. Paroxysmal itch caused by gain-of-function Nav1.7 mutation.
Pain, 2014 Sep , 155 (1702-7).

233

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Shi D et al. Reduction in dynamin-2 is implicated in ischaemic cardiac arrhythmias.
J. Cell. Mol. Med., 2014 Oct , 18 (1992-9).

237

238

Dhalla AK et al. Blockade of Na+ channels in pancreatic α-cells has antidiabetic effects.
Diabetes, 2014 Oct , 63 (3545-56).

241

Foadi N et al. A combination of topical antiseptics for the treatment of sore throat blocks voltage-gated neuronal sodium channels.
Naunyn Schmiedebergs Arch. Pharmacol., 2014 Oct , 387 (991-1000).

242

Hoeijmakers JG et al. Channelopathies, painful neuropathy, and diabetes: which way does the causal arrow point?
Trends Mol Med, 2014 Oct , 20 (544-50).

247

Wang X et al. Angiotensin-(1-7) prevent atrial tachycardia induced sodium channel remodeling.
Pacing Clin Electrophysiol, 2014 Oct , 37 (1349-56).

248

Liu M et al. Cardiac sodium channel mutations: why so many phenotypes?
Nat Rev Cardiol, 2014 Oct , 11 (607-15).

254

255

Chatin B et al. Dynamitin affects cell-surface expression of voltage-gated sodium channel Nav1.5.
Biochem. J., 2014 Nov 1 , 463 (339-49).

256

Zhang Q et al. Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.
J. Physiol. (Lond.), 2014 Nov 1 , 592 (4677-96).

258

Savio-Galimberti E et al. SCN10A/Nav1.8 modulation of peak and late sodium currents in patients with early onset atrial fibrillation.
Cardiovasc. Res., 2014 Nov 1 , 104 (355-63).

260

263

de Kovel CG et al. Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy.
Epilepsy Res., 2014 Nov , 108 (1511-8).

266

267

Frolov RV et al. Celecoxib and ion channels: a story of unexpected discoveries.
Eur. J. Pharmacol., 2014 May 5 , 730 (61-71).

269

Kiss T et al. Down regulation of sodium channels in the central nervous system of hibernating snails.
Physiol. Behav., 2014 May 28 , 131 (93-8).

272

Gilchrist J et al. Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents.
ACS Chem. Biol., 2014 May 16 , 9 (1204-12).

274

Zhang YY et al. Characterization of functional ion channels in human cardiac c-kit+ progenitor cells.
Basic Res. Cardiol., 2014 May , 109 (407).

276

277

Holzherr B et al. A gating model for wildtype and R1448H Nav1.4 channels in paramyotonia.
Acta Myol, 2014 May , 33 (22-33).

279

Dhamija R et al. Sleep abnormalities in children with Dravet syndrome.
Pediatr. Neurol., 2014 May , 50 (474-8).

280

Lin CR et al. Intrathecal miR-183 delivery suppresses mechanical allodynia in mononeuropathic rats.
Eur. J. Neurosci., 2014 May , 39 (1682-9).

284

Chen R et al. Mechanism of tetrodotoxin block and resistance in sodium channels.
Biochem. Biophys. Res. Commun., 2014 Mar 28 , 446 (370-4).

285

Thériault O et al. Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate.
Eur. J. Pharmacol., 2014 Mar 15 , 727 (158-66).

289

Black JA et al. Nav1.9 expression in magnocellular neurosecretory cells of supraoptic nucleus.
Exp. Neurol., 2014 Mar , 253 (174-9).

290

Matalon D et al. Confirming an expanded spectrum of SCN2A mutations: a case series.
Epileptic Disord, 2014 Mar , 16 (13-8).

291

Elíes J et al. Inhibition of the cardiac Na⁺ channel Nav1.5 by carbon monoxide.
J. Biol. Chem., 2014 Jun 6 , 289 (16421-9).

292

295

Coleman N et al. New Positive KCa Channel Gating Modulators with Selectivity for KCa3.1.
Mol. Pharmacol., 2014 Jun 23 , ().

298

Ben-Johny M et al. Conservation of Ca(2+)/Calmodulin Regulation across Na and Ca(2+) Channels.
Cell, 2014 Jun 19 , 157 (1657-70).

300

Nutter TJ et al. Persistent modification of Nav1.9 following chronic exposure to insecticides and pyridostigmine bromide.
Toxicol. Appl. Pharmacol., 2014 Jun 15 , 277 (298-309).

301

Bagnéris C et al. Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.
Proc. Natl. Acad. Sci. U.S.A., 2014 Jun 10 , 111 (8428-33).

303

Qi B et al. Nav1.8 channels in ganglionated plexi modulate atrial fibrillation inducibility.
Cardiovasc. Res., 2014 Jun 1 , 102 (480-6).

304

Bennett DL et al. Painful and painless channelopathies.
Lancet Neurol, 2014 Jun , 13 (587-99).

307

Zeng Q et al. [Src family kinases affect the expression of Nav1.1 in spiral ganglion neurons].
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 2014 Jun , 28 (789-92).

310

312

Foadi N et al. Inhibition of voltage-gated Na⁺ channels by the synthetic cannabinoid ajulemic acid.
Anesth. Analg., 2014 Jun , 118 (1238-45).

313

Alday A et al. Ionic channels underlying the ventricular action potential in zebrafish embryo.
Pharmacol. Res., 2014 Jun , 84 (26-31).

317

Hu D et al. Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.
J. Am. Coll. Cardiol., 2014 Jul 8 , 64 (66-79).

320

Dybkova N et al. Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa.
Cardiovasc. Res., 2014 Jul 1 , 103 (168-77).

324

Minett MS et al. Pain without nociceptors? Nav1.7-independent pain mechanisms.
Cell Rep, 2014 Jan 30 , 6 (301-12).

328

332

Shorer Z et al. A novel mutation in SCN9A in a child with congenital insensitivity to pain.
Pediatr. Neurol., 2014 Jan , 50 (73-6).

334

Gajewiak J et al. A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ.
Proc. Natl. Acad. Sci. U.S.A., 2014 Feb 18 , 111 (2758-63).

340

Vanoye CG et al. Novel SCN3A variants associated with focal epilepsy in children.
Neurobiol. Dis., 2014 Feb , 62 (313-22).

342

Xu L et al. [Expression of voltage gated sodium channel Nav1.9 in experimental pulpal lesions in the rats].
Zhonghua Kou Qiang Yi Xue Za Zhi, 2014 Feb , 49 (95-100).

344

Schroder EA et al. Light phase-restricted feeding slows basal heart rate to exaggerate the type-3 long QT syndrome phenotype in mice.
Am. J. Physiol. Heart Circ. Physiol., 2014 Dec 15 , 307 (H1777-85).

346

Savio-Galimberti E et al. Atrial Fibrillation and SCN5A Variants.
Card Electrophysiol Clin, 2014 Dec 1 , 6 (741-748).

349

Yang Q et al. Persistent pain after spinal cord injury is maintained by primary afferent activity.
J. Neurosci., 2014 Aug 6 , 34 (10765-9).

350

Huang WF et al. Role of sodium channels in the spontaneous excitability of early embryonic cardiomyocytes.
Chin J Physiol, 2014 Aug 31 , 57 (188-97).

355

Bouafia A et al. Axonal expression of sodium channels and neuropathology of the plaques in multiple sclerosis.
Neuropathol. Appl. Neurobiol., 2014 Aug , 40 (579-90).

362

Makinson CD et al. Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.
Neurobiol. Dis., 2014 Aug , 68 (16-25).

364

Brauner JM et al. Risperidone inhibits voltage-gated sodium channels.
Eur. J. Pharmacol., 2014 Apr 5 , 728 (100-6).

366

Themistocleous AC et al. The clinical approach to small fibre neuropathy and painful channelopathy.
Pract Neurol, 2014 Apr 28 , ().

368

370

Abriel H et al. Unexpected α-α interactions with NaV1.5 genetic variants in Brugada syndrome.
Circ Cardiovasc Genet, 2014 Apr 1 , 7 (97-9).

373

Senatore A et al. Cav3 T-type channels: regulators for gating, membrane expression, and cation selectivity.
Pflugers Arch., 2014 Apr , 466 (645-60).

374

Kruse M et al. TRPM4 channels in the cardiovascular system.
Curr Opin Pharmacol, 2014 Apr , 15 (68-73).

375

376

Vasylyev DV et al. Dynamic-clamp analysis of wild-type human Nav1.7 and erythromelalgia mutant channel L858H.
J. Neurophysiol., 2014 Apr , 111 (1429-43).

380

Moreau A et al. Biophysics, pathophysiology, and pharmacology of ion channel gating pores.
Front Pharmacol, 2014 , 5 (53).

382

Laedermann CJ et al. Ubiquitylation of voltage-gated sodium channels.
Handb Exp Pharmacol, 2014 , 221 (231-50).

383

386

Thakur M et al. Defining the nociceptor transcriptome.
Front Mol Neurosci, 2014 , 7 (87).

390

Jones DK et al. Proton modulation of cardiac I Na: a potential arrhythmogenic trigger.
Handb Exp Pharmacol, 2014 , 221 (169-81).

397

Zimmer T et al. Voltage-gated sodium channels in the mammalian heart.
Glob Cardiol Sci Pract, 2014 , 2014 (449-63).

401

Mahdavi S et al. Systematic study of binding of μ-conotoxins to the sodium channel NaV1.4.
Toxins (Basel), 2014 , 6 (3454-70).

412

Gabelli SB et al. Regulation of the NaV1.5 cytoplasmic domain by calmodulin.
Nat Commun, 2014 , 5 (5126).

415

Minett MS et al. Significant determinants of mouse pain behaviour.
PLoS ONE, 2014 , 9 (e104458).

420

421

Elkins RC et al. Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment.
J Pharmacol Toxicol Methods, 2013 Jul-Aug , 68 (112-22).

422

Morissette P et al. The anesthetized guinea pig: An effective early cardiovascular derisking and lead optimization model.
J Pharmacol Toxicol Methods, 2013 Jul-Aug , 68 (137-49).

425

Chiu IM et al. Bacteria activate sensory neurons that modulate pain and inflammation.
Nature, 2013 Sep 5 , 501 (52-7).

429

431

Hernãndez-Ochoa EO et al. Elevated nuclear Foxo1 suppresses excitability of skeletal muscle fibers.
Am. J. Physiol., Cell Physiol., 2013 Sep 15 , 305 (C643-53).

433

Shryock JC et al. The arrhythmogenic consequences of increasing late INa in the cardiomyocyte.
Cardiovasc. Res., 2013 Sep 1 , 99 (600-11).

439

Xiao M et al. FGF14 localization and organization of the axon initial segment.
Mol. Cell. Neurosci., 2013 Sep , 56 (393-403).

446

449

Black JA et al. Noncanonical roles of voltage-gated sodium channels.
Neuron, 2013 Oct 16 , 80 (280-91).

450

Sheets MF et al. Outward stabilization of the voltage sensor in domain II but not domain I speeds inactivation of voltage-gated sodium channels.
Am. J. Physiol. Heart Circ. Physiol., 2013 Oct 15 , 305 (H1213-21).

452

455

Wu M et al. A naturally occurring amino acid substitution in the voltage-dependent sodium channel selectivity filter affects channel gating.
J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol., 2013 Oct , 199 (829-42).

456

Zhang XY et al. Gain-of-function mutations in SCN11A cause familial episodic pain.
Am. J. Hum. Genet., 2013 Nov 7 , 93 (957-66).

459

Daou I et al. Remote optogenetic activation and sensitization of pain pathways in freely moving mice.
J. Neurosci., 2013 Nov 20 , 33 (18631-40).

461

Zhao ZQ et al. Chronic itch development in sensory neurons requires BRAF signaling pathways.
J. Clin. Invest., 2013 Nov 1 , 123 (4769-80).

465

Cox JJ et al. No pain, more gain.
Nat. Genet., 2013 Nov , 45 (1271-2).

467

471

Oakley JC et al. Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome.
J. Pharmacol. Exp. Ther., 2013 May , 345 (215-24).

474

Kim JJ et al. Bradycardia alters Ca(2+) dynamics enhancing dispersion of repolarization and arrhythmia risk.
Am. J. Physiol. Heart Circ. Physiol., 2013 Mar 15 , 304 (H848-60).

475

Estacion M et al. A new Nav1.7 mutation in an erythromelalgia patient.
Biochem. Biophys. Res. Commun., 2013 Mar 1 , 432 (99-104).

476

Luo Y et al. [Inhibitory effect of NaV1.9 gene silencing on proliferation, phagocytosis and migration in RAW264.7 cells].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2013 Mar , 29 (225-8).

480

Driscoll HE et al. Pumilio-2 regulates translation of Nav1.6 to mediate homeostasis of membrane excitability.
J. Neurosci., 2013 Jun 5 , 33 (9644-54).

487

Bender AC et al. Focal Scn1a knockdown induces cognitive impairment without seizures.
Neurobiol. Dis., 2013 Jun , 54 (297-307).

489

Nilsson MF et al. Comparative effects of sodium channel blockers in short term rat whole embryo culture.
Toxicol. Appl. Pharmacol., 2013 Jul 8 , ().

493

Ravens U et al. Atrial selectivity of antiarrhythmic drugs.
J. Physiol. (Lond.), 2013 Jul 16 , ().

494

Du Y et al. Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel.
Proc. Natl. Acad. Sci. U.S.A., 2013 Jul 16 , 110 (11785-90).

495

McCormack K et al. Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.
Proc. Natl. Acad. Sci. U.S.A., 2013 Jul 16 , 110 (E2724-32).

497

Takanari H et al. Efficient and specific cardiac IK1 inhibition by a new pentamidine analogue.
Cardiovasc. Res., 2013 Jul 1 , 99 (203-14).

498

Tsunozaki M et al. A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.
J. Physiol. (Lond.), 2013 Jul 1 , 591 (3325-40).

499

Gillet L et al. NaV1.5 and interacting proteins in human arrhythmogenic cardiomyopathy.
Future Cardiol, 2013 Jul , 9 (467-70).

504

Waxman SG Painful Na-channelopathies: an expanding universe.
Trends Mol Med, 2013 Jul , 19 (406-9).

506

Zhang Q et al. [Desmoplakin expression silencing affects cardiac voltage-gated sodium channel Nav1.5 in HL-1 cells].
Nan Fang Yi Ke Da Xue Xue Bao, 2013 Jul , 33 (983-9).

509

Ramachandra R et al. NaV1.8 channels are expressed in large, as well as small, diameter sensory afferent neurons.
Channels (Austin), 2013 Jan 1 , 7 (34-7).

512

515

516

Vanoye CG et al. Mechanism of sodium channel NaV1.9 potentiation by G-protein signaling.
J. Gen. Physiol., 2013 Feb , 141 (193-202).

518

Zhang LM et al. [Association between mutations of SCN9A gene and pain related to Parkinsonism].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2013 Feb , 30 (17-20).

519

Harris RA et al. Human metastable epiallele candidates link to common disorders.
Epigenetics, 2013 Feb , 8 (157-63).

522

Tanzi S et al. Ion channel recordings on an injection-molded polymer chip.
Lab Chip, 2013 Dec 21 , 13 (4784-93).

523

Gilchrist J et al. Crystallographic insights into sodium-channel modulation by the β4 subunit.
Proc. Natl. Acad. Sci. U.S.A., 2013 Dec 17 , 110 (E5016-24).

525

Staunton CA et al. Ion channels and osteoarthritic pain: potential for novel analgesics.
Curr Pain Headache Rep, 2013 Dec , 17 (378).

528

Doppler K et al. [Neuropathic pain associated with Nav1.7 mutations: clinical picture and treatment].
Nervenarzt, 2013 Dec , 84 (1428-35).

531

Dustrude ET et al. CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking.
J. Biol. Chem., 2013 Aug 23 , 288 (24316-31).

532

Bradley E et al. The cardiac sodium current Na(v)1.5 is functionally expressed in rabbit bronchial smooth muscle cells.
Am. J. Physiol., Cell Physiol., 2013 Aug 15 , 305 (C427-35).

533

534

Stevens M et al. Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.
J. Neuroimmunol., 2013 Aug 15 , 261 (21-8).

535

Liu S et al. Altered PKA modulation in the Nav1.1 epilepsy variant I1656M.
J. Neurophysiol., 2013 Aug 14 , ().

536

Li A et al. Genetic biomarkers in Brugada syndrome.
Biomark Med, 2013 Aug , 7 (535-46).

538

Kaufmann SG et al. Distribution and function of sodium channel subtypes in human atrial myocardium.
J. Mol. Cell. Cardiol., 2013 Aug , 61 (133-41).

543

Rhett JM et al. The perinexus: sign-post on the path to a new model of cardiac conduction?
Trends Cardiovasc. Med., 2013 Aug , 23 (222-8).

547

Crotti L et al. Long QT syndrome-associated mutations in intrauterine fetal death.
JAMA, 2013 Apr 10 , 309 (1473-82).

548

Kalume F et al. Sudden unexpected death in a mouse model of Dravet syndrome.
J. Clin. Invest., 2013 Apr 1 , 123 (1798-808).

550

Black JA et al. Nav1.5 sodium channels in macrophages in multiple sclerosis lesions.
Mult. Scler., 2013 Apr , 19 (532-42).

551

553

Hegyi B et al. Selectivity problems with drugs acting on cardiac Na⁺ and Ca²⁺ channels.
Curr. Med. Chem., 2013 , 20 (2552-71).

564

Auerbach DS et al. Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome.
PLoS ONE, 2013 , 8 (e77843).

566

Nakatani Y et al. Effect of lamotrigine on Na(v)1.4 voltage-gated sodium channels.
J. Pharmacol. Sci., 2013 , 123 (203-6).

579

Cejudo-Román A et al. The voltage-gated sodium channel nav1.8 is expressed in human sperm.
PLoS ONE, 2013 , 8 (e76084).

594

Tao R et al. [Expression of Nav1.8 in human dental pulp].
Zhonghua Kou Qiang Yi Xue Za Zhi, 2012 Mar , 47 (177-81).

595

Catalano A et al. An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite.
Drug Metab Lett, 2012 Jun 1 , 6 (124-8).

596

Liu P et al. Modulation of neuronal sodium channels by the sea anemone peptide BDS-I.
J. Neurophysiol., 2012 Jun , 107 (3155-67).

599

601

Kim YS et al. Expression of transient receptor potential ankyrin 1 in human dental pulp.
J Endod, 2012 Aug , 38 (1087-92).

602

Song W et al. Cardiac sodium channel Nav1.5 mutations and cardiac arrhythmia.
Pediatr Cardiol, 2012 Aug , 33 (943-9).

603

Gao XF et al. Sigma-1 receptor agonists directly inhibit Nav1.2/1.4 channels.
PLoS ONE, 2012 , 7 (e49384).

605

Akiyama M et al. Dravet syndrome: a genetic epileptic disorder.
Acta Med. Okayama, 2012 , 66 (369-76).

612

Mert T et al. Antinociceptive activities of lidocaine and the nav1.8 blocker a803467 in diabetic rats.
J. Am. Assoc. Lab. Anim. Sci., 2012 , 51 (579-85).