Channelpedia

IA in play.


Authors: Scott M Thompson

Journal, date & volume: Neuron, 2007 Jun 21 , 54, 850-2

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/17582324

Channelpedia reference in: Kv4.3

Abstract
Everyone agrees about how long-term potentiation (LTP) is induced-NMDA receptor activation-but much remains to be learned about how the increase in the strength of a synaptic connection between two neurons is expressed. In this issue of Neuron, Kim et al. report a new form of NMDAR-dependent plasticity that may contribute to LTP: internalization of postsynaptic Kv4.2 potassium channels that mediate transient IA-type outward current in dendrites.