PubMed 17582324

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Title: IA in play.

Authors: Scott M Thompson

Journal, date & volume: Neuron, 2007 Jun 21 , 54, 850-2

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Everyone agrees about how long-term potentiation (LTP) is induced-NMDA receptor activation-but much remains to be learned about how the increase in the strength of a synaptic connection between two neurons is expressed. In this issue of Neuron, Kim et al. report a new form of NMDAR-dependent plasticity that may contribute to LTP: internalization of postsynaptic Kv4.2 potassium channels that mediate transient IA-type outward current in dendrites.