Channelpedia

Cloning and functional expression of a TEA-sensitive A-type potassium channel from rat brain.


Authors: K H Schröter, J P Ruppersberg, F Wunder, J Rettig, M Stocker, O Pongs

Journal, date & volume: FEBS Lett., 1991 Jan 28 , 278, 211-6

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/1840526

Channelpedia reference in: Kv4.1

Abstract
A rat brain cDNA (Raw3) related to the Drosophila Shaw K+ channel family has been characterized. Raw3 cRNA leads to the formation of TEA-insensitive, fast inactivating (A-type) K+ channels when injected into Xenopus laevis oocytes. Raw3 channels have markedly different properties from the previously cloned rat A-type K+ channel RCK4, Raw3 channels operate in the positive voltage range.