Channelpedia

Nav1.8 Channel

289 automatically matched literature references

2

Han C et al. Sodium channel Nav1.8: Emerging links to human disease.
Neurology, 2016 Feb 2 , 86 (473-83).

7

Wang X et al. Characterization of Specific Roles of Sodium Channel Subtypes in Regional Anesthesia.
Reg Anesth Pain Med, 2015 Sep-Oct , 40 (599-604).

13

Patel R et al. Ionic Mechanisms of Spinal Neuronal Cold Hypersensitivity in Ciguatera.
Eur. J. Neurosci., 2015 Oct 10 , ().

15

Han Z et al. The effects of A-803467 on cardiac Nav1.5 channels.
Eur. J. Pharmacol., 2015 May 5 , 754 (52-60).

19

24

Talbot S et al. Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.
Neuron, 2015 Jul 15 , 87 (341-54).

27

Baruteau AE et al. Inherited progressive cardiac conduction disorders.
Curr. Opin. Cardiol., 2015 Jan , 30 (33-9).

31

Jabbari J et al. Common and rare variants in SCN10A modulate the risk of atrial fibrillation.
Circ Cardiovasc Genet, 2015 Feb , 8 (64-73).

33

Habib AM et al. Sodium channels and pain.
Handb Exp Pharmacol, 2015 , 227 (39-56).

39

Doran C et al. Mouse DRG Cell Line with Properties of Nociceptors.
PLoS ONE, 2015 , 10 (e0128670).

42

Hirofuji S et al. Role of sodium channels in recovery of sciatic nerve-stretch injury in rats.
Muscle Nerve, 2014 Sep , 50 (425-30).

44

Savio-Galimberti E et al. SCN10A/Nav1.8 modulation of peak and late sodium currents in patients with early onset atrial fibrillation.
Cardiovasc. Res., 2014 Nov 1 , 104 (355-63).

46

Kiss T et al. Down regulation of sodium channels in the central nervous system of hibernating snails.
Physiol. Behav., 2014 May 28 , 131 (93-8).

50

Andreasen L et al. Brugada syndrome risk loci seem protective against atrial fibrillation.
Eur. J. Hum. Genet., 2014 Mar 26 , ().

51

Thériault O et al. Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate.
Eur. J. Pharmacol., 2014 Mar 15 , 727 (158-66).

53

Black JA et al. Nav1.9 expression in magnocellular neurosecretory cells of supraoptic nucleus.
Exp. Neurol., 2014 Mar , 253 (174-9).

54

57

Nutter TJ et al. Persistent modification of Nav1.9 following chronic exposure to insecticides and pyridostigmine bromide.
Toxicol. Appl. Pharmacol., 2014 Jun 15 , 277 (298-309).

58

Qi B et al. Nav1.8 channels in ganglionated plexi modulate atrial fibrillation inducibility.
Cardiovasc. Res., 2014 Jun 1 , 102 (480-6).

59

Bennett DL et al. Painful and painless channelopathies.
Lancet Neurol, 2014 Jun , 13 (587-99).

60

61

Foadi N et al. Inhibition of voltage-gated Na⁺ channels by the synthetic cannabinoid ajulemic acid.
Anesth. Analg., 2014 Jun , 118 (1238-45).

63

Brouwer BA et al. Painful neuropathies: the emerging role of sodium channelopathies.
J. Peripher. Nerv. Syst., 2014 Jun , 19 (53-65).

64

Hu D et al. Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.
J. Am. Coll. Cardiol., 2014 Jul 8 , 64 (66-79).

65

Minett MS et al. Pain without nociceptors? Nav1.7-independent pain mechanisms.
Cell Rep, 2014 Jan 30 , 6 (301-12).

69

Yang Q et al. Persistent pain after spinal cord injury is maintained by primary afferent activity.
J. Neurosci., 2014 Aug 6 , 34 (10765-9).

70

Bagal SK et al. Recent progress in sodium channel modulators for pain.
Bioorg. Med. Chem. Lett., 2014 Aug 15 , 24 (3690-9).

71

Themistocleous AC et al. The clinical approach to small fibre neuropathy and painful channelopathy.
Pract Neurol, 2014 Apr 28 , ().

72

van den Boogaard M et al. A common genetic variant within SCN10A modulates cardiac SCN5A expression.
J. Clin. Invest., 2014 Apr 1 , 124 (1844-52).

73

Park DS et al. Nav-igating through a complex landscape: SCN10A and cardiac conduction.
J. Clin. Invest., 2014 Apr 1 , 124 (1460-2).

75

Laedermann CJ et al. Ubiquitylation of voltage-gated sodium channels.
Handb Exp Pharmacol, 2014 , 221 (231-50).

76

Thakur M et al. Defining the nociceptor transcriptome.
Front Mol Neurosci, 2014 , 7 (87).

80

Zimmer T et al. Voltage-gated sodium channels in the mammalian heart.
Glob Cardiol Sci Pract, 2014 , 2014 (449-63).

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Minett MS et al. Significant determinants of mouse pain behaviour.
PLoS ONE, 2014 , 9 (e104458).

87

Chiu IM et al. Bacteria activate sensory neurons that modulate pain and inflammation.
Nature, 2013 Sep 5 , 501 (52-7).

94

Zhang XY et al. Gain-of-function mutations in SCN11A cause familial episodic pain.
Am. J. Hum. Genet., 2013 Nov 7 , 93 (957-66).

96

Daou I et al. Remote optogenetic activation and sensitization of pain pathways in freely moving mice.
J. Neurosci., 2013 Nov 20 , 33 (18631-40).

97

Zhao ZQ et al. Chronic itch development in sensory neurons requires BRAF signaling pathways.
J. Clin. Invest., 2013 Nov 1 , 123 (4769-80).

102

Waxman SG Painful Na-channelopathies: an expanding universe.
Trends Mol Med, 2013 Jul , 19 (406-9).

103

Ramachandra R et al. NaV1.8 channels are expressed in large, as well as small, diameter sensory afferent neurons.
Channels (Austin), 2013 Jan 1 , 7 (34-7).

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van den Boogaard M et al. From GWAS to function: Genetic variation in sodium channel gene enhancer influences electrical patterning.
Trends Cardiovasc. Med., 2013 Dec 17 , ().

107

van Duijvenboden K et al. Gene regulatory elements of the cardiac conduction system.
Brief Funct Genomics, 2013 Aug 22 , ().

114

Cejudo-Román A et al. The voltage-gated sodium channel nav1.8 is expressed in human sperm.
PLoS ONE, 2013 , 8 (e76084).

116

Numann RE et al. Letter to the editor on NaV1.8.
Circ. Res., 2012 Sep 28 , 111 (e230; author reply e231).

118

Faber CG et al. Gain-of-function Nav1.8 mutations in painful neuropathy.
Proc. Natl. Acad. Sci. U.S.A., 2012 Nov 20 , 109 (19444-9).

120

Raouf R et al. Sodium channels and mammalian sensory mechanotransduction.
, 2012 Mar 26 , 8 (21).

122

Tao R et al. [Expression of Nav1.8 in human dental pulp].
Zhonghua Kou Qiang Yi Xue Za Zhi, 2012 Mar , 47 (177-81).

125

Yang T et al. Blocking scn10a channels in heart reduces late sodium current and is antiarrhythmic.
Circ. Res., 2012 Jul 20 , 111 (322-32).

126

London B Whither art thou, SCN10A, and what art thou doing?
Circ. Res., 2012 Jul 20 , 111 (268-70).

128

van den Boogaard M et al. Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.
J. Clin. Invest., 2012 Jul 2 , 122 (2519-30).

133

Shields SD et al. A channelopathy contributes to cerebellar dysfunction in a model of multiple sclerosis.
Ann. Neurol., 2012 Feb , 71 (186-94).

135

Gilchrist J et al. Animal toxins can alter the function of Nav1.8 and Nav1.9.
Toxins (Basel), 2012 Aug , 4 (620-32).

137

Kim YS et al. Expression of transient receptor potential ankyrin 1 in human dental pulp.
J Endod, 2012 Aug , 38 (1087-92).

143

Mert T et al. Antinociceptive activities of lidocaine and the nav1.8 blocker a803467 in diabetic rats.
J. Am. Assoc. Lab. Anim. Sci., 2012 , 51 (579-85).

144

Gautron L et al. Genetic tracing of Nav1.8-expressing vagal afferents in the mouse.
J. Comp. Neurol., 2011 Oct 15 , 519 (3085-101).

150

Shou WT et al. [Role of voltage-sodium channels in neuropathic pain].
Zhejiang Da Xue Xue Bao Yi Xue Ban, 2011 Mar , 40 (217-21).

153

Widmark J et al. Differential evolution of voltage-gated sodium channels in tetrapods and teleost fishes.
Mol. Biol. Evol., 2011 Jan , 28 (859-71).

155

Ho C et al. Single-cell analysis of sodium channel expression in dorsal root ganglion neurons.
Mol. Cell. Neurosci., 2011 Jan , 46 (159-66).

159

Wilson MJ et al. Navβ subunits modulate the inhibition of Nav1.8 by the analgesic gating modifier μO-conotoxin MrVIB.
J. Pharmacol. Exp. Ther., 2011 Aug , 338 (687-93).

160

Zhao J et al. Regulation of Nav1.6 and Nav1.8 peripheral nerve Na+ channels by auxiliary β-subunits.
J. Neurophysiol., 2011 Aug , 106 (608-19).

162

Smith JG et al. Genome-wide association studies of the PR interval in African Americans.
PLoS Genet., 2011 , 7 (e1001304).

171

Lampert A et al. Sodium channelopathies and pain.
Pflugers Arch., 2010 Jul , 460 (249-63).

173

Pfeufer A et al. Genome-wide association study of PR interval.
Nat. Genet., 2010 Feb , 42 (153-9).

174

Chambers JC et al. Genetic variation in SCN10A influences cardiac conduction.
Nat. Genet., 2010 Feb , 42 (149-52).

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184

Herold KF et al. Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.
Anesthesiology, 2009 Sep , 111 (591-9).

185

Priest BT Future potential and status of selective sodium channel blockers for the treatment of pain.
Curr Opin Drug Discov Devel, 2009 Sep , 12 (682-92).

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Zhang L et al. [Nav1.8 and Nav1.9 mRNA expression in rat trigeminal ganglion at different interval after molar extraction].
Zhonghua Kou Qiang Yi Xue Za Zhi, 2009 May , 44 (301-3).

192

Black JA et al. Sodium channel activity modulates multiple functions in microglia.
Glia, 2009 Aug 1 , 57 (1072-81).

193

Browne LE et al. Structural determinants of drugs acting on the Nav1.8 channel.
J. Biol. Chem., 2009 Apr 17 , 284 (10523-36).

195

Browne LE et al. Functional and pharmacological properties of human and rat NaV1.8 channels.
Neuropharmacology, 2009 Apr , 56 (905-14).

200

Wang CF et al. Use of bulleyaconitine A as an adjuvant for prolonged cutaneous analgesia in the rat.
Anesth. Analg., 2008 Oct , 107 (1397-405).

205

Dray A Neuropathic pain: emerging treatments.
, 2008 Jul , 101 (48-58).

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Abrahamsen B et al. The cell and molecular basis of mechanical, cold, and inflammatory pain.
Science, 2008 Aug 1 , 321 (702-5).

214

Krafte DS et al. Block of Nav1.8 by small molecules.
Channels (Austin), 2007 May-Jun , 1 (152-3).

215

Yang SW et al. Novel steroidal saponins, Sch 725737 and Sch 725739, from a marine starfish, Novodinia antillensis.
Bioorg. Med. Chem. Lett., 2007 Oct 15 , 17 (5543-7).

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Zimmermann K et al. Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures.
Nature, 2007 Jun 14 , 447 (855-8).

222

Williams BS et al. Characterization of a new class of potent inhibitors of the voltage-gated sodium channel Nav1.7.
Biochemistry, 2007 Dec 18 , 46 (14693-703).

225

Dray A et al. Arthritis and pain. Future targets to control osteoarthritis pain.
Arthritis Res. Ther., 2007 , 9 (212).

227

Rogers M et al. The role of sodium channels in neuropathic pain.
Semin. Cell Dev. Biol., 2006 Oct , 17 (571-81).

229

Cardenas CA et al. Carbamazepine interacts with a slow inactivation state of NaV1.8-like sodium channels.
Neurosci. Lett., 2006 Nov 13 , 408 (129-34).

230

Rush AM et al. A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons.
Proc. Natl. Acad. Sci. U.S.A., 2006 May 23 , 103 (8245-50).

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Devaux JJ et al. Altered ion channels in an animal model of Charcot-Marie-Tooth disease type IA.
J. Neurosci., 2005 Feb 9 , 25 (1470-80).

246

Dekker LV et al. Analysis of human Nav1.8 expressed in SH-SY5Y neuroblastoma cells.
Eur. J. Pharmacol., 2005 Dec 28 , 528 (52-8).

252

Beyak MJ et al. Two TTX-resistant Na+ currents in mouse colonic dorsal root ganglia neurons and their role in colitis-induced hyperexcitability.
Am. J. Physiol. Gastrointest. Liver Physiol., 2004 Oct , 287 (G845-55).

253

Wood JN et al. Voltage-gated sodium channels and pain pathways.
J. Neurobiol., 2004 Oct , 61 (55-71).

254

Bosmans F et al. The poison Dart frog's batrachotoxin modulates Nav1.8.
FEBS Lett., 2004 Nov 5 , 577 (245-8).

255

Schwab Y et al. Expression of tetrodotoxin-sensitive and resistant sodium channels by rat melanotrophs.
Neuroreport, 2004 May 19 , 15 (1219-23).

256

Coste B et al. Gating and modulation of presumptive NaV1.9 channels in enteric and spinal sensory neurons.
Mol. Cell. Neurosci., 2004 May , 26 (123-34).

260

Vijayaragavan K et al. Role of auxiliary beta1-, beta2-, and beta3-subunits and their interaction with Na(v)1.8 voltage-gated sodium channel.
Biochem. Biophys. Res. Commun., 2004 Jun 25 , 319 (531-40).

262

Casula MA et al. Expression of the sodium channel beta3 subunit in injured human sensory neurons.
Neuroreport, 2004 Jul 19 , 15 (1629-32).

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Tympanidis P et al. Increased vanilloid receptor VR1 innervation in vulvodynia.
, 2004 Apr , 8 (129-33).

266

Lai J et al. Voltage-gated sodium channels and hyperalgesia.
Annu. Rev. Pharmacol. Toxicol., 2004 , 44 (371-97).

267

Klein JP et al. Patterned electrical activity modulates sodium channel expression in sensory neurons.
J. Neurosci. Res., 2003 Oct 15 , 74 (192-8).

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Malik-Hall M et al. Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8.
Brain Res. Mol. Brain Res., 2003 Feb 20 , 110 (298-304).

274

Zhou X et al. Vinpocetine is a potent blocker of rat NaV1.8 tetrodotoxin-resistant sodium channels.
J. Pharmacol. Exp. Ther., 2003 Aug , 306 (498-504).

276

Laird JM et al. Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)-null mice.
J. Neurosci., 2002 Oct 1 , 22 (8352-6).

280

Ogata N et al. Molecular diversity of structure and function of the voltage-gated Na+ channels.
Jpn. J. Pharmacol., 2002 Apr , 88 (365-77).

281

Rasband MN et al. Distinct potassium channels on pain-sensing neurons.
Proc. Natl. Acad. Sci. U.S.A., 2001 Nov 6 , 98 (13373-8).

284

Jeong SY et al. Identification of a novel human voltage-gated sodium channel alpha subunit gene, SCN12A.
Biochem. Biophys. Res. Commun., 2000 Jan 7 , 267 (262-70).

287

Oaklander AL et al. Unilateral nerve injury down-regulates mRNA for Na+ channel SCN10A bilaterally in rat dorsal root ganglia.
Brain Res. Mol. Brain Res., 1997 Dec 1 , 52 (162-5).

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