Channelpedia

ClvC5 Channel

262 automatically matched literature references

2

Devuyst O et al. Chloride transporters and receptor-mediated endocytosis in the renal proximal tubule.
J. Physiol. (Lond.), 2015 Sep 15 , 593 (4151-64).

5

Greenlee MM et al. Prolactin stimulates sodium and chloride ion channels in A6 renal epithelial cells.
Am. J. Physiol. Renal Physiol., 2015 Jan 13 , (ajprenal.00270.2014).

6

Jian S et al. [Clinical and genetic analysis of Dent disease in 4 Chinese children].
Zhongguo Dang Dai Er Ke Za Zhi, 2015 Dec , 17 (1261-6).

7

8

Mansour-Hendili L et al. Mutation Update of the CLCN5 Gene Responsible for Dent Disease 1.
Hum. Mutat., 2015 Aug , 36 (743-52).

9

Lee A et al. Chloride channel ClC-5 binds to aspartyl aminopeptidase to regulate renal albumin endocytosis.
Am. J. Physiol. Renal Physiol., 2015 Apr 1 , 308 (F784-92).

12

Cramer MT et al. Expanding the phenotype of proteinuria in Dent disease. A case series.
Pediatr. Nephrol., 2014 Oct , 29 (2051-4).

13

Pusch M et al. ClC-5: Physiological role and biophysical mechanisms.
Cell Calcium, 2014 Nov 13 , ().

14

Park E et al. Muscle involvement in Dent disease 2.
Pediatr. Nephrol., 2014 Nov , 29 (2127-32).

16

18

Ji LN et al. A novel CLCN5 mutation in a Chinese boy with Dent's disease.
World J Pediatr, 2014 Aug , 10 (275-7).

20

Platt C et al. Dent's disease complicated by an acute Budd-Chiari syndrome.
BMJ Case Rep, 2014 , 2014 ().

21

Duan X Ion Channels, Channelopathies, and Tooth Formation.
J. Dent. Res., 2013 Sep 27 , ().

23

24

26

De Stefano S et al. A single point mutation reveals gating of the human ClC-5 Cl-/H+ antiporter.
J. Physiol. (Lond.), 2013 Dec 1 , 591 (5879-93).

27

Ochoa-de la Paz LD et al. Characterization of an outward rectifying chloride current of Xenopus tropicalis oocytes.
Biochim. Biophys. Acta, 2013 Aug , 1828 (1743-53).

30

Zifarelli G et al. On the mechanism of gating charge movement of ClC-5, a human Cl(-)/H(+) antiporter.
Biophys. J., 2012 May 2 , 102 (2060-9).

31

Grieschat M et al. Glutamate 268 regulates transport probability of the anion/proton exchanger ClC-5.
J. Biol. Chem., 2012 Mar 9 , 287 (8101-9).

32

34

Stauber T et al. Cell biology and physiology of CLC chloride channels and transporters.
Compr Physiol, 2012 Jul , 2 (1701-44).

35

Lourdel S et al. ClC-5 mutations associated with Dent's disease: a major role of the dimer interface.
Pflugers Arch., 2012 Feb , 463 (247-56).

37

Coulibaly G et al. [Dent's syndrome. Nephrology follow-up of four patients of the same family].
Nephrol. Ther., 2012 Apr , 8 (92-5).

41

Claverie-Martín F et al. Dent's disease: clinical features and molecular basis.
Pediatr. Nephrol., 2011 May , 26 (693-704).

42

43

De Stefano S et al. Extracellular determinants of anion discrimination of the Cl-/H+ antiporter protein CLC-5.
J. Biol. Chem., 2011 Dec 23 , 286 (44134-44).

44

Fong P Thyroid iodide efflux: a team effort?
J. Physiol. (Lond.), 2011 Dec 15 , 589 (5929-39).

46

Tseng PY et al. Binding of ATP to the CBS domains in the C-terminal region of CLC-1.
J. Gen. Physiol., 2011 Apr , 137 (357-68).

47

Grand T et al. Heterogeneity in the processing of CLCN5 mutants related to Dent disease.
Hum. Mutat., 2011 Apr , 32 (476-83).

48

Simske JS et al. Claudin family proteins in Caenorhabditis elegans.
Methods Mol. Biol., 2011 , 762 (147-69).

49

Jouret F et al. Segmental and subcellular distribution of CFTR in the kidney.
Methods Mol. Biol., 2011 , 741 (285-99).

50

Wang H et al. Osteogenic role of endosomal chloride channels in MC3T3-E1 cells.
Mol. Cell. Biochem., 2010 Sep , 342 (191-9).

51

Stauber T et al. Sorting motifs of the endosomal/lysosomal CLC chloride transporters.
J. Biol. Chem., 2010 Nov 5 , 285 (34537-48).

52

Bogdanović R et al. A novel CLCN5 mutation in a boy with Bartter-like syndrome and partial growth hormone deficiency.
Pediatr. Nephrol., 2010 Nov , 25 (2363-8).

56

Smith AJ et al. Direct endosomal acidification by the outwardly rectifying CLC-5 Cl(-)/H(+) exchanger.
J. Physiol. (Lond.), 2010 Jun 15 , 588 (2033-45).

58

Cao L et al. Chloride channels and transporters in human corneal epithelium.
Exp. Eye Res., 2010 Jun , 90 (771-9).

59

Picollo A et al. Proton block of the CLC-5 Cl-/H+ exchanger.
J. Gen. Physiol., 2010 Jun , 135 (653-9).

63

64

Tian M et al. Chloride channels regulate chondrogenesis in chicken mandibular mesenchymal cells.
Arch. Oral Biol., 2010 Dec , 55 (938-45).

67

Devuyst O et al. Dent's disease.
Orphanet J Rare Dis, 2010 , 5 (28).

68

Carraro-Lacroix LR et al. Role of CFTR and ClC-5 in modulating vacuolar H+-ATPase activity in kidney proximal tubule.
Cell. Physiol. Biochem., 2010 , 26 (563-76).

69

Sethi SK et al. Vitamin A responsive night blindness in Dent's disease.
Pediatr. Nephrol., 2009 Sep , 24 (1765-70).

71

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Zifarelli G et al. Intracellular regulation of human ClC-5 by adenine nucleotides.
EMBO Rep., 2009 Oct , 10 (1111-6).

75

Plans V et al. Physiological roles of CLC Cl(-)/H (+) exchangers in renal proximal tubules.
Pflugers Arch., 2009 May , 458 (23-37).

80

Stechman MJ et al. Genetic causes of hypercalciuric nephrolithiasis.
Pediatr. Nephrol., 2009 Dec , 24 (2321-32).

81

Frishberg Y et al. Dent's disease manifesting as focal glomerulosclerosis: Is it the tip of the iceberg?
Pediatr. Nephrol., 2009 Dec , 24 (2369-73).

82

Duan X et al. ClC-5 regulates dentin development through TGF-beta1 pathway.
Arch. Oral Biol., 2009 Dec , 54 (1118-24).

83

Bergsdorf EY et al. Residues important for nitrate/proton coupling in plant and mammalian CLC transporters.
J. Biol. Chem., 2009 Apr 24 , 284 (11184-93).

85

Jouret F et al. CFTR and defective endocytosis: new insights in the renal phenotype of cystic fibrosis.
Pflugers Arch., 2009 Apr , 457 (1227-36).

86

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Shrimpton AE et al. OCRL1 mutations in Dent 2 patients suggest a mechanism for phenotypic variability.
Nephron Physiol, 2009 , 112 (p27-36).

89

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Hou J et al. ClC chloride channels in tooth germ and odontoblast-like MDPC-23 cells.
Arch. Oral Biol., 2008 Sep , 53 (874-8).

91

Osteen JD et al. Insights into the ClC-4 transport mechanism from studies of Zn2+ inhibition.
Biophys. J., 2008 Nov 15 , 95 (4668-75).

92

Wright J et al. Transcriptional adaptation to Clcn5 knockout in proximal tubules of mouse kidney.
Physiol. Genomics, 2008 May 13 , 33 (341-54).

93

Sheffer-Babila S et al. Growth hormone improves growth rate and preserves renal function in Dent disease.
J. Pediatr. Endocrinol. Metab., 2008 Mar , 21 (279-86).

94

96

Matsuda JJ et al. Overexpression of CLC-3 in HEK293T cells yields novel currents that are pH dependent.
Am. J. Physiol., Cell Physiol., 2008 Jan , 294 (C251-62).

97

Zdebik AA et al. Determinants of anion-proton coupling in mammalian endosomal CLC proteins.
J. Biol. Chem., 2008 Feb 15 , 283 (4219-27).

98

Cho HY et al. Renal manifestations of Dent disease and Lowe syndrome.
Pediatr. Nephrol., 2008 Feb , 23 (243-9).

99

Pavićević S et al. [Dent's disease]
Srp Arh Celok Lek, 2008 Dec , 136 Suppl 4 (312-5).

103

Meyer S et al. Nucleotide recognition by the cytoplasmic domain of the human chloride transporter ClC-5.
Nat. Struct. Mol. Biol., 2007 Jan , 14 (60-7).

104

Jentsch TJ Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters.
J. Physiol. (Lond.), 2007 Feb 1 , 578 (633-40).

108

Zifarelli G et al. CLC chloride channels and transporters: a biophysical and physiological perspective.
Rev. Physiol. Biochem. Pharmacol., 2007 , 158 (23-76).

111

Wellhauser L et al. Nucleotides bind to the C-terminus of ClC-5.
Biochem. J., 2006 Sep 1 , 398 (289-94).

112

Ludwig M et al. Hypercalciuria in patients with CLCN5 mutations.
Pediatr. Nephrol., 2006 Sep , 21 (1241-50).

113

Tosetto E et al. Phenotypic and genetic heterogeneity in Dent's disease--the results of an Italian collaborative study.
Nephrol. Dial. Transplant., 2006 Sep , 21 (2452-63).

114

Sile S et al. Molecular physiology of renal ClC chloride channels/transporters.
Curr. Opin. Nephrol. Hypertens., 2006 Sep , 15 (511-6).

116

118

Damodaran TV et al. Toxicogenomic studies of the rat brain at an early time point following acute sarin exposure.
Neurochem. Res., 2006 Mar , 31 (367-81).

120

Maritzen T et al. Kidney-specific upregulation of vitamin D3 target genes in ClC-5 KO mice.
Kidney Int., 2006 Jul , 70 (79-87).

121

Milliner DS Stones, bones, and heredity.
Acta Paediatr Suppl, 2006 Jul , 95 (27-30).

122

Pusch M et al. Channel or transporter? The CLC saga continues.
Exp. Physiol., 2006 Jan , 91 (149-52).

124

Utsch B et al. Novel OCRL1 mutations in patients with the phenotype of Dent disease.
Am. J. Kidney Dis., 2006 Dec , 48 (942.e1-14).

125

De Angeli A et al. The nitrate/proton antiporter AtCLCa mediates nitrate accumulation in plant vacuoles.
Nature, 2006 Aug 24 , 442 (939-42).

126

Maritzen T et al. ClC-5 does not affect megalin expression and function in the thyroid.
Thyroid, 2006 Aug , 16 (725-30).

127

Hryciw DH et al. ClC-5: a chloride channel with multiple roles in renal tubular albumin uptake.
Int. J. Biochem. Cell Biol., 2006 , 38 (1036-42).

130

Wang Y et al. ClC-5: role in endocytosis in the proximal tubule.
Am. J. Physiol. Renal Physiol., 2005 Oct , 289 (F850-62).

131

Rebelo MA et al. Screening for CLCN5 mutation in renal calcium stone formers patients.
An. Acad. Bras. Cienc., 2005 Mar , 77 (95-101).

132

Ernest NJ et al. Relative contribution of chloride channels and transporters to regulatory volume decrease in human glioma cells.
Am. J. Physiol., Cell Physiol., 2005 Jun , 288 (C1451-60).

133

Jentsch TJ Chloride transport in the kidney: lessons from human disease and knockout mice.
J. Am. Soc. Nephrol., 2005 Jun , 16 (1549-61).

135

Picollo A et al. Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.
Nature, 2005 Jul 21 , 436 (420-3).

136

139

Mummery JL et al. Expression of the chloride channel CLC-K in human airway epithelial cells.
Can. J. Physiol. Pharmacol., 2005 Dec , 83 (1123-8).

141

Hara-Chikuma M et al. Impaired acidification in early endosomes of ClC-5 deficient proximal tubule.
Biochem. Biophys. Res. Commun., 2005 Apr 15 , 329 (941-6).

142

Cheong HI et al. Phenotype and genotype of Dent's disease in three Korean boys.
Pediatr. Nephrol., 2005 Apr , 20 (455-9).

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Pham PC et al. Hypertonicity increases CLC-5 expression in mouse medullary thick ascending limb cells.
Am. J. Physiol. Renal Physiol., 2004 Oct , 287 (F747-52).

148

Brakemeier S et al. Dent's disease: identification of a novel mutation in the renal chloride channel CLCN5.
Clin. Nephrol., 2004 Nov , 62 (387-90).

149

Mo L et al. ClC-5 chloride channel alters expression of the epithelial sodium channel (ENaC).
J. Membr. Biol., 2004 Nov , 202 (21-37).

151

Hoopes RR et al. Evidence for genetic heterogeneity in Dent's disease.
Kidney Int., 2004 May , 65 (1615-20).

153

Santo Y et al. Examination of megalin in renal tubular epithelium from patients with Dent disease.
Pediatr. Nephrol., 2004 Jun , 19 (612-5).

161

Davies N et al. Chloride channel gene expression in the rabbit cornea.
Mol. Vis., 2004 Dec 30 , 10 (1028-37).

162

Reyes JP et al. Novel outwardly rectifying anion conductance in Xenopus oocytes.
Pflugers Arch., 2004 Dec , 449 (271-7).

163

Jiang B et al. Expression and roles of Cl- channel ClC-5 in cell cycles of myeloid cells.
Biochem. Biophys. Res. Commun., 2004 Apr 23 , 317 (192-7).

165

Langman CB The molecular basis of kidney stones.
Curr. Opin. Pediatr., 2004 Apr , 16 (188-93).

167

Thakker R Dent's disease--a nephrolithiasis disorder associated with defective receptor-mediated endocytosis.
Bull. Mem. Acad. R. Med. Belg., 2004 , 159 (199-211).

168

Devuyst O Chloride channels and endocytosis: new insights from Dent's disease and CLC-5 knockout mice.
Bull. Mem. Acad. R. Med. Belg., 2004 , 159 (212-7).

170

Carr G et al. A role for CBS domain 2 in trafficking of chloride channel CLC-5.
Biochem. Biophys. Res. Commun., 2003 Oct 17 , 310 (600-5).

171

Hryciw DH et al. Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines.
J. Biol. Chem., 2003 Oct 10 , 278 (40169-76).

172

Furukawa T [Various functions of ClC-type Cl- channels]
Nippon Yakurigaku Zasshi, 2003 Nov , 122 (375-83).

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175

Flores SY et al. The role of Nedd4/Nedd4-like dependant ubiquitylation in epithelial transport processes.
Pflugers Arch., 2003 Jun , 446 (334-8).

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177

Olsen ML et al. Expression of voltage-gated chloride channels in human glioma cells.
J. Neurosci., 2003 Jul 2 , 23 (5572-82).

178

Sayer JA et al. Disordered calcium crystal handling in antisense CLC-5-treated collecting duct cells.
Biochem. Biophys. Res. Commun., 2003 Jan 10 , 300 (305-10).

179

Isnard-Bagnis C et al. Detection of ClC-3 and ClC-5 in epididymal epithelium: immunofluorescence and RT-PCR after LCM.
Am. J. Physiol., Cell Physiol., 2003 Jan , 284 (C220-32).

180

Günther W et al. The ClC-5 chloride channel knock-out mouse - an animal model for Dent's disease.
Pflugers Arch., 2003 Jan , 445 (456-62).

181

Mohammad-Panah R et al. The chloride channel ClC-4 contributes to endosomal acidification and trafficking.
J. Biol. Chem., 2003 Aug 1 , 278 (29267-77).

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185

Carballo-Trujillo I et al. Novel truncating mutations in the ClC-5 chloride channel gene in patients with Dent's disease.
Nephrol. Dial. Transplant., 2003 Apr , 18 (717-23).

186

Hebeisen S et al. Anion permeation in human ClC-4 channels.
Biophys. J., 2003 Apr , 84 (2306-18).

189

Weng TX et al. Oxidant and antioxidant modulation of chloride channels expressed in human retinal pigment epithelium.
Am. J. Physiol., Cell Physiol., 2002 Sep , 283 (C839-49).

190

Schmieder S et al. Cloning and characterisation of amphibian ClC-3 and ClC-5 chloride channels.
Biochim. Biophys. Acta, 2002 Nov 13 , 1566 (55-66).

191

Edmonds RD et al. ClC-5: ontogeny of an alternative chloride channel in respiratory epithelia.
Am. J. Physiol. Lung Cell Mol. Physiol., 2002 Mar , 282 (L501-7).

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194

Sayer JA et al. Urinary stone formation: Dent's disease moves understanding forward.
Exp. Nephrol., 2002 , 10 (176-81).

198

Weylandt KH et al. Human ClC-3 is not the swelling-activated chloride channel involved in cell volume regulation.
J. Biol. Chem., 2001 May 18 , 276 (17461-7).

199

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Sasaki Y et al. Expression of chloride channel, ClC-5, and its role in receptor-mediated endocytosis of albumin in OK cells.
Biochem. Biophys. Res. Commun., 2001 Mar 23 , 282 (212-8).

201

Silva IV et al. ClC-5 chloride channel and kidney stones: what is the link?
Braz. J. Med. Biol. Res., 2001 Mar , 34 (315-23).

203

Weng TX et al. Expression and regulation of ClC-5 chloride channels: effects of antisense and oxidants.
Am. J. Physiol., Cell Physiol., 2001 Jun , 280 (C1511-20).

206

Vandewalle A et al. Tissue distribution and subcellular localization of the ClC-5 chloride channel in rat intestinal cells.
Am. J. Physiol., Cell Physiol., 2001 Feb , 280 (C373-81).

207

Obermüller N et al. An endocytosis defect as a possible cause of proteinuria in polycystic kidney disease.
Am. J. Physiol. Renal Physiol., 2001 Feb , 280 (F244-53).

208

Morimoto T et al. A new approach to mRNA in proximal tubule cells of patients with CLCN5 channelopathy.
Pediatr. Nephrol., 2001 Feb , 16 (110-2).

209

Schmieder S et al. Tissue-specific N-glycosylation of the ClC-3 chloride channel.
Biochem. Biophys. Res. Commun., 2001 Aug 24 , 286 (635-40).

210

Duffy SM et al. Voltage-dependent and calcium-activated ion channels in the human mast cell line HMC-1.
J. Leukoc. Biol., 2001 Aug , 70 (233-40).

211

Schwake M et al. An internalization signal in ClC-5, an endosomal Cl-channel mutated in dent's disease.
J. Biol. Chem., 2001 Apr 13 , 276 (12049-54).

213

217

Uchida S In vivo role of CLC chloride channels in the kidney.
Am. J. Physiol. Renal Physiol., 2000 Nov , 279 (F802-8).

218

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Scheinman SJ et al. Isolated hypercalciuria with mutation in CLCN5: relevance to idiopathic hypercalciuria.
Kidney Int., 2000 Jan , 57 (232-9).

221

Silva IV et al. PTH regulates expression of ClC-5 chloride channel in the kidney.
Am. J. Physiol. Renal Physiol., 2000 Feb , 278 (F238-45).

222

224

Wills NK et al. Chloride channel expression in cultured human fetal RPE cells: response to oxidative stress.
Invest. Ophthalmol. Vis. Sci., 2000 Dec , 41 (4247-55).

226

Yamamoto K et al. Characterization of renal chloride channel (CLCN5) mutations in Dent's disease.
J. Am. Soc. Nephrol., 2000 Aug , 11 (1460-8).

227

228

Schwingshackl A et al. Involvement of ion channels in human eosinophil respiratory burst.
J. Allergy Clin. Immunol., 2000 Aug , 106 (272-9).

229

Cox JP et al. Renal chloride channel, CLCN5, mutations in Dent's disease.
J. Bone Miner. Res., 1999 Sep , 14 (1536-42).

230

231

Lamb FS et al. Expression of CLCN voltage-gated chloride channel genes in human blood vessels.
J. Mol. Cell. Cardiol., 1999 Mar , 31 (657-66).

233

Friedrich T et al. Mutational analysis demonstrates that ClC-4 and ClC-5 directly mediate plasma membrane currents.
J. Biol. Chem., 1999 Jan 8 , 274 (896-902).

238

von Weikersthal SF et al. Functional and molecular characterization of a volume-sensitive chloride current in rat brain endothelial cells.
J. Physiol. (Lond.), 1999 Apr 1 , 516 ( Pt 1) (75-84).

240

241

Thakker RV Chloride channels in renal disease.
Adv. Nephrol. Necker Hosp., 1999 , 29 (289-98).

244

Morimoto T et al. Mutations in CLCN5 chloride channel in Japanese patients with low molecular weight proteinuria.
J. Am. Soc. Nephrol., 1998 May , 9 (811-8).

245

George AL Chloride channels and endocytosis: ClC-5 makes a dent.
Proc. Natl. Acad. Sci. U.S.A., 1998 Jul 7 , 95 (7843-5).

247

Thakker RV The role of renal chloride channel mutations in kidney stone disease and nephrocalcinosis.
Curr. Opin. Nephrol. Hypertens., 1998 Jul , 7 (385-8).

248

Kumar R CLC-5 chloride channels and renal disease.
Kidney Int., 1998 Jan , 53 (228-9).

252

Eggermont J The exon-intron architecture of human chloride channel genes is not conserved.
Biochim. Biophys. Acta, 1998 Apr 29 , 1397 (156-60).

255

Lindenthal S et al. Cloning and functional expression of a ClC Cl- channel from the renal cell line A6.
Am. J. Physiol., 1997 Oct , 273 (C1176-85).

257

Oudet C et al. A second family with XLRH displays the mutation S244L in the CLCN5 gene.
Hum. Genet., 1997 Jun , 99 (781-4).

259

Lloyd SE et al. A common molecular basis for three inherited kidney stone diseases.
Nature, 1996 Feb 1 , 379 (445-9).

262

Steinmeyer K et al. Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease.
J. Biol. Chem., 1995 Dec 29 , 270 (31172-7).