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All references automaticaly matched for SK1

306. Pubmed Xu S. et al. A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis. Oncotarget, 2016 May 14 , ().
305. Pubmed Tauseef M. et al. Transient receptor potential channel 1 maintains adherens junction plasticity by suppressing sphingosine kinase 1 expression to induce endothelial hyperpermeability. FASEB J., 2016 Jan , 30 (102-10).
304. Pubmed Pisani D. et al. The K+ channel TASK1 modulates β-adrenergic response in brown adipose tissue through the mineralocorticoid receptor pathway. FASEB J., 2016 Feb , 30 (909-22).
303. Pubmed Gandolfi B. et al. A dominant TRPV4 variant underlies osteochondrodysplasia in Scottish fold cats. Osteoarthr. Cartil., 2016 Apr 6 , ().
302. Pubmed Rahman M. et al. Electrophysiological characterization of voltage-dependent calcium currents and TRPV4 currents in human pulmonary fibroblasts. Am. J. Physiol. Lung Cell Mol. Physiol., 2016 Apr 1 , 310 (L603-14).
301. Pubmed Zhao Y. et al. Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells. BMC Cardiovasc Disord, 2016 , 16 (1).
300. Pubmed Bhuyan R. et al. Molecular dynamics of Kv1.3 ion channel and structural basis of its inhibition by scorpion toxin-OSK1 derivatives. Biophys. Chem., 2015 Aug-Sep , 203-204 (1-11).
299. Pubmed Jo A. et al. TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia. J. Neurosci., 2015 Sep 30 , 35 (13525-37).
298. Pubmed Mizukami K. et al. Small-conductance Ca2+-activated K+ current is upregulated via the phosphorylation of CaMKII in cardiac hypertrophy from spontaneously hypertensive rats. Am. J. Physiol. Heart Circ. Physiol., 2015 Sep 15 , 309 (H1066-74).
297. Pubmed Carretero L. et al. ERK and RSK are necessary for TRH-induced inhibition of r-ERG potassium currents in rat pituitary GH3 cells. Cell. Signal., 2015 Sep , 27 (1720-30).
296. Pubmed Rajasekhar P. et al. P2Y1 receptor activation of the TRPV4 ion channel enhances purinergic signaling in satellite glial cells. J. Biol. Chem., 2015 Oct 16 , ().
295. Pubmed Hurd L. et al. A mutation in TRPV4 results in altered chondrocyte calcium signaling in severe metatropic dysplasia. Am. J. Med. Genet. A, 2015 Oct , 167A (2286-93).
294. Pubmed Gao M. et al. Synthesis of [(11)C]GSK1482160 as a new PET agent for targeting P2X(7) receptor. Bioorg. Med. Chem. Lett., 2015 May 1 , 25 (1965-70).
293. Pubmed Buckler K. et al. TASK channels in arterial chemoreceptors and their role in oxygen and acid sensing. Pflugers Arch., 2015 May , 467 (1013-25).
292. Pubmed Ehling P. et al. The CNS under pathophysiologic attack--examining the role of K₂p channels. Pflugers Arch., 2015 May , 467 (959-72).
291. Pubmed Bandulik S. et al. Two-pore domain potassium channels in the adrenal cortex. Pflugers Arch., 2015 May , 467 (1027-42).
290. Pubmed Göb E. et al. The two-pore domain potassium channel KCNK5 deteriorates outcome in ischemic neurodegeneration. Pflugers Arch., 2015 May , 467 (973-87).
289. Pubmed De Clercq K. et al. Functional expression of transient receptor potential channels in human endometrial stromal cells during the luteal phase of the menstrual cycle. Hum. Reprod., 2015 Mar 27 , ().
288. Pubmed Teng J. et al. L596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel. Proc. Natl. Acad. Sci. U.S.A., 2015 Mar 17 , 112 (3386-91).
287. Pubmed Yi F. et al. Down-regulation of the small conductance calcium-activated potassium channels in diabetic mouse atria. J. Biol. Chem., 2015 Mar 13 , 290 (7016-26).
286. Pubmed Deng Y. et al. Magnolol and honokiol regulate the calcium-activated potassium channels signaling pathway in Enterotoxigenic Escherichia coli-induced diarrhea mice. Eur. J. Pharmacol., 2015 Mar 11 , ().
285. Pubmed Larson R. et al. Sympathoexcitation in ANG II-salt hypertension involves reduced SK channel function in the hypothalamic paraventricular nucleus. Am. J. Physiol. Heart Circ. Physiol., 2015 Jun 15 , 308 (H1547-55).
284. Pubmed Narita K. et al. TRPV4 regulates the integrity of the blood-cerebrospinal fluid barrier and modulates transepithelial protein transport. FASEB J., 2015 Jun , 29 (2247-59).
283. Pubmed Wilson P. et al. Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel. Mol. Endocrinol., 2015 Jun , 29 (896-908).
282. Pubmed Alkozi H. et al. TRPV4 activation triggers the release of melatonin from human non-pigmented ciliary epithelial cells. Exp. Eye Res., 2015 Jul , 136 (34-7).
281. Pubmed Cabral P. et al. TRPV4 mediates flow-induced increases in intracellular Ca in medullary thick ascending limbs. Acta Physiol (Oxf), 2015 Jul , 214 (319-28).
280. Pubmed Padula A. et al. KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction. Neuropsychopharmacology, 2015 Jul , 40 (1928-39).
279. Pubmed Song J. et al. The effect of ASK1 on vascular permeability and edema formation in cerebral ischemia. Brain Res., 2015 Jan 21 , 1595 (143-55).
278. Pubmed Dragoni S. et al. A functional transient receptor potential vanilloid 4 (TRPV4) channel is expressed in human endothelial progenitor cells. J. Cell. Physiol., 2015 Jan , 230 (95-104).
277. Pubmed Singh V. et al. Molecular and functional characterization of TRPV4 channels in pregnant and nonpregnant mouse uterus. Life Sci., 2015 Feb 1 , 122 (51-8).
276. Pubmed Church T. et al. Preferential assembly of heteromeric small conductance calcium-activated potassium channels. Eur. J. Neurosci., 2015 Feb , 41 (305-15).
275. Pubmed Chen L. et al. Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature. Acta Physiol (Oxf), 2015 Feb , 213 (481-91).
274. Pubmed Suresh K. et al. Hydrogen peroxide-induced calcium influx in lung microvascular endothelial cells involves TRPV4. Am. J. Physiol. Lung Cell Mol. Physiol., 2015 Dec 15 , 309 (L1467-77).
273. Pubmed Baratchi S. et al. Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells. Cell. Mol. Life Sci., 2015 Aug 20 , ().
272. Pubmed Matsuoka H. et al. Src mediates endocytosis of TWIK-related acid-sensitive K+ 1 channels in PC12 cells in response to nerve growth factor. Am. J. Physiol., Cell Physiol., 2015 Aug 15 , 309 (C251-63).
271. Pubmed Ru F. et al. Acid sensitivity of the spinal dorsal root ganglia C-fiber nociceptors innervating the guinea pig esophagus. Neurogastroenterol. Motil., 2015 Apr 5 , ().
270. Pubmed Aidi-Knani S. et al. Correspondences between the binding characteristics of a non-natural peptide, Lei-Dab7, and the distribution of SK subunits in the rat central nervous system. Eur. J. Pharmacol., 2015 Apr 5 , 752 (106-11).
269. Pubmed Farberov L. et al. MicroRNA-mediated regulation of p21 and TASK1 cellular restriction factors enhances HIV-1 infection. J. Cell. Sci., 2015 Apr 15 , 128 (1607-16).
268. Pubmed Adapala R. et al. Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy. Oncogene, 2015 Apr 13 , ().
267. Pubmed Doleschal B. et al. TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1. Cardiovasc. Res., 2015 Apr 1 , 106 (163-73).
266. Pubmed Feetham C. et al. TRPV4 and KCa ion channels functionally couple as osmosensors in the paraventricular nucleus. Br. J. Pharmacol., 2015 Apr , 172 (1753-68).
265. Pubmed Sostegni S. et al. Sensitisation of TRPV4 by PAR2 is independent of intracellular calcium signalling and can be mediated by the biased agonist neutrophil elastase. Pflugers Arch., 2015 Apr , 467 (687-701).
264. Pubmed Thoppil R. et al. TRPV4 channel activation selectively inhibits tumor endothelial cell proliferation. Sci Rep, 2015 , 5 (14257).
263. Pubmed Monaghan K. et al. Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium. PLoS ONE, 2015 , 10 (e0128359).
262. Pubmed Jie P. et al. Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways. Cell Death Dis, 2015 , 6 (e1775).
261. Pubmed Kim I. et al. Possible Role of TRP Channels in Rat Glomus Cells. Adv. Exp. Med. Biol., 2015 , 860 (227-32).
260. Pubmed Buckler K. et al. Functional Properties of Mitochondria in the Type-1 Cell and Their Role in Oxygen Sensing. Adv. Exp. Med. Biol., 2015 , 860 (69-80).
259. Pubmed Nayak P. et al. Mechanotransduction via TRPV4 regulates inflammation and differentiation in fetal mouse distal lung epithelial cells. Respir. Res., 2015 , 16 (60).
258. Pubmed Te Molder L. et al. PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736. PLoS ONE, 2015 , 10 (e0143357).
257. Pubmed Cabral P. et al. TRPV4 activation mediates flow-induced nitric oxide production in the rat thick ascending limb. Am. J. Physiol. Renal Physiol., 2014 Sep 15 , 307 (F666-72).
256. Pubmed Egbuniwe O. et al. TRPA1 and TRPV4 activation in human odontoblasts stimulates ATP release. J. Dent. Res., 2014 Sep , 93 (911-7).
255. Pubmed Takayama Y. et al. Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1. FASEB J., 2014 May , 28 (2238-48).
254. Pubmed Mercado J. et al. Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle. J. Gen. Physiol., 2014 May , 143 (559-75).
253. Pubmed Yu L. et al. Neuroprotective effect of muscone on glutamate-induced apoptosis in PC12 cells via antioxidant and Ca(2+) antagonism. Neurochem. Int., 2014 May , 70 (10-21).
252. Pubmed Guéguinou M. et al. KCa and Ca(2+) channels: The complex thought. Biochim. Biophys. Acta, 2014 Mar 6 , ().
251. Pubmed Tran V. et al. Mechanotransduction channels of the trabecular meshwork. Curr. Eye Res., 2014 Mar , 39 (291-303).
250. Pubmed Merrill L. et al. Intravesical TRPV4 blockade reduces repeated variate stress (RVS)-induced bladder dysfunction by increasing bladder capacity and decreasing voiding frequency. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2014 Jun 25 , ().
249. Pubmed Skibsbye L. et al. Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria. Cardiovasc. Res., 2014 Jul 1 , 103 (156-67).
248. Pubmed Ochoa-Cortés F. et al. Potential for developing purinergic drugs for gastrointestinal diseases. Inflamm. Bowel Dis., 2014 Jul , 20 (1259-87).
247. Pubmed O'Conor C. et al. TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading. Proc. Natl. Acad. Sci. U.S.A., 2014 Jan 28 , 111 (1316-21).
246. Pubmed El Hachmane M. et al. Enhancement of TWIK-related Acid-sensitive Potassium Channel 3 (TASK3) Two-pore Domain Potassium Channel Activity by Tumor Necrosis Factor α. J. Biol. Chem., 2014 Jan 17 , 289 (1388-401).
245. Pubmed Pankey E. et al. Analysis of responses to the TRPV4 agonist GSK1016790A in the pulmonary vascular bed of the intact-chest rat. Am. J. Physiol. Heart Circ. Physiol., 2014 Jan 1 , 306 (H33-40).
244. Pubmed Jablonski C. et al. Integrin α1β1 participates in chondrocyte transduction of osmotic stress. Biochem. Biophys. Res. Commun., 2014 Feb 28 , 445 (184-90).
243. Pubmed Zhang X. et al. Critical roles of a small conductance Ca²⁺-activated K⁺ channel (SK3) in the repolarization process of atrial myocytes. Cardiovasc. Res., 2014 Feb 1 , 101 (317-25).
242. Pubmed Dufour M. et al. Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development. J. Neurosci. Res., 2014 Aug , 92 (981-99).
241. Pubmed Grace M. et al. The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2 -induced Activation of TRPV4 In Vitro and Pain In Vivo. Br. J. Pharmacol., 2014 Apr 30 , ().
240. Pubmed Gymnopoulos M. et al. Developmental mapping of small-conductance calcium-activated potassium channel expression in the rat nervous system. J. Comp. Neurol., 2014 Apr 1 , 522 (1072-101).
239. Pubmed McAlexander M. et al. Transient receptor potential vanilloid 4 activation constricts the human bronchus via the release of cysteinyl leukotrienes. J. Pharmacol. Exp. Ther., 2014 Apr , 349 (118-25).
238. Pubmed Shenton F. et al. A study of the expression of small conductance calcium-activated potassium channels (SK1-3) in sensory endings of muscle spindles and lanceolate endings of hair follicles in the rat. PLoS ONE, 2014 , 9 (e107073).
237. Pubmed Dolga A. et al. Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons. Cell Death Dis, 2014 , 5 (e999).
236. Pubmed Son S. et al. Reduced IRE1α mediates apoptotic cell death by disrupting calcium homeostasis via the InsP3 receptor. Cell Death Dis, 2014 , 5 (e1188).
235. Pubmed Cabo R. et al. Calcium-activated potassium channel SK1 is widely expressed in the peripheral nervous system and sensory organs of adult zebrafish. Neurosci. Lett., 2013 Sep 21 , ().
234. Pubmed Alenmyr L. et al. TRPV4-mediated calcium influx and ciliary activity in human native airway epithelial cells. Basic Clin. Pharmacol. Toxicol., 2013 Sep 11 , ().
233. Pubmed de Haan J. et al. Lipid-rich enteral nutrition regulates mucosal mast cell activation via the vagal anti-inflammatory reflex. Am. J. Physiol. Gastrointest. Liver Physiol., 2013 Sep 1 , 305 (G383-91).
232. Pubmed Kieseier B. et al. Targeting two-pore domain potassium channels - a promising strategy for treating T cell mediated autoimmunity. Exp. Neurol., 2013 Sep , 247 (286-8).
231. Pubmed Liu Y. et al. Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle. Cell. Signal., 2013 Sep , 25 (1877-86).
230. Pubmed Chen R. et al. Molecular dynamics simulations of scorpion toxin recognition by the Ca(2+)-activated potassium channel KCa3.1. Biophys. J., 2013 Oct 15 , 105 (1829-37).
229. Pubmed Xi B. et al. Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population. Clin. Endocrinol. (Oxf), 2013 Oct , 79 (523-8).
228. Pubmed Zhang L. et al. Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease. Br. J. Pharmacol., 2013 Oct , 170 (661-70).
227. Pubmed Qi X. et al. Role of Small Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog. Circulation, 2013 Nov 4 , ().
226. Pubmed Pollema-Mays S. et al. Expression of background potassium channels in rat DRG is cell-specific and down-regulated in a neuropathic pain model. Mol. Cell. Neurosci., 2013 Nov , 57 (1-9).
225. Pubmed Wu W. et al. EGFR tyrosine kinase regulates human small-conductance Ca2+-activated K+ (hSKCa1) channels expressed in HEK-293 cells. Biochem. J., 2013 May 15 , 452 (121-9).
224. Pubmed Linta L. et al. Calcium activated potassium channel expression during human iPS cell-derived neurogenesis. Ann. Anat., 2013 Jul , 195 (303-11).
223. Pubmed Matsuoka H. et al. Nerve growth factor-induced endocytosis of TWIK-related acid-sensitive K⁺ 1 channels in adrenal medullary cells and PC12 cells. Pflugers Arch., 2013 Jul , 465 (1051-64).
222. Pubmed Dreses-Werringloer U. et al. CALHM1 controls Ca2+-dependent MEK/ERK/RSK/MSK signaling in neurons. J. Cell. Sci., 2013 Jan 23 , ().
221. Pubmed Mubagwa K. et al. Signalling between G-protein-coupled receptors and TASK1 channels. Cardiovasc. Res., 2013 Jan 1 , 97 (10-2).
220. Pubmed Al Ghouleh I. et al. Aquaporin 1, Nox1, and Ask1 mediate oxidant-induced smooth muscle cell hypertrophy. Cardiovasc. Res., 2013 Jan 1 , 97 (134-42).
219. Pubmed Ali Z. et al. Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects. Br J Clin Pharmacol, 2013 Jan , 75 (197-207).
218. Pubmed Alexander R. et al. 4α-phorbol 12,13-didecanoate activates cultured mouse dorsal root ganglia neurons independently of TRPV4. Br. J. Pharmacol., 2013 Feb , 168 (761-72).
217. Pubmed Young J. et al. The passive and active contractile properties of the neurogenic, underactive bladder. BJU Int., 2013 Feb , 111 (355-61).
216. Pubmed Schmidt C. et al. Class I antiarrhythmic drugs inhibit human cardiac two-pore-domain K(+) (K2 ₂p) channels. Eur. J. Pharmacol., 2013 Dec 5 , 721 (237-48).
215. Pubmed Sukumaran S. et al. TRPV4 channel activation leads to endothelium-dependent relaxation mediated by nitric oxide and endothelium-derived hyperpolarizing factor in rat pulmonary artery. Pharmacol. Res., 2013 Dec , 78 (18-27).
214. Pubmed Ni Y. et al. Bisoprolol reversed small conductance calcium-activated potassium channel (SK) remodeling in a volume-overload rat model. Mol. Cell. Biochem., 2013 Dec , 384 (95-103).
213. Pubmed Pagadala P. et al. Loss of NR1 subunit of NMDARs in primary sensory neurons leads to hyperexcitability and pain hypersensitivity: involvement of Ca(2+)-activated small conductance potassium channels. J. Neurosci., 2013 Aug 14 , 33 (13425-30).
212. Pubmed Parajuli S. et al. NS309 decreases rat detrusor smooth muscle membrane potential and phasic contractions by activating SK3 channels. Br. J. Pharmacol., 2013 Apr , 168 (1611-25).
211. Pubmed Atkinson A. et al. Functional, anatomical, and molecular investigation of the cardiac conduction system and arrhythmogenic atrioventricular ring tissue in the rat heart. J Am Heart Assoc, 2013 , 2 (e000246).
210. Pubmed Lübbert M. et al. Transient receptor potential channels encode volatile chemicals sensed by rat trigeminal ganglion neurons. PLoS ONE, 2013 , 8 (e77998).
209. Pubmed Corrêa S. et al. MSK1 regulates homeostatic and experience-dependent synaptic plasticity. J. Neurosci., 2012 Sep 19 , 32 (13039-51).
208. Pubmed Andres M. et al. Glucose-sensitivity of the afterhyperpolarization potential: role of SK1 channel in insulin-secreting cells. Gen. Comp. Endocrinol., 2012 Sep 15 , 178 (459-62).
207. Pubmed Inoue M. et al. Mechanisms and roles of muscarinic activation in guinea-pig adrenal medullary cells. Am. J. Physiol., Cell Physiol., 2012 Sep 15 , 303 (C635-44).
206. Pubmed Sullivan M. et al. Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells. Mol. Pharmacol., 2012 Sep , 82 (464-72).
205. Pubmed Schmidt C. et al. Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels. Naunyn Schmiedebergs Arch. Pharmacol., 2012 Oct , 385 (1003-16).
204. Pubmed Vandael D. et al. Ca(V)1.3-driven SK channel activation regulates pacemaking and spike frequency adaptation in mouse chromaffin cells. J. Neurosci., 2012 Nov 14 , 32 (16345-59).
203. Pubmed Murphy N. et al. The neuroprotective effect of a specific P2X₇ receptor antagonist derives from its ability to inhibit assembly of the NLRP3 inflammasome in glial cells. Brain Pathol., 2012 May , 22 (295-306).
202. Pubmed Chen R. et al. Engineering a potent and specific blocker of voltage-gated potassium channel Kv1.3, a target for autoimmune diseases. Biochemistry, 2012 Mar 6 , 51 (1976-82).
201. Pubmed Berrout J. et al. Function of transient receptor potential cation channel subfamily V member 4 (TRPV4) as a mechanical transducer in flow-sensitive segments of renal collecting duct system. J. Biol. Chem., 2012 Mar 16 , 287 (8782-91).
200. Pubmed Marsh B. et al. Leak K⁺ channel mRNAs in dorsal root ganglia: relation to inflammation and spontaneous pain behaviour. Mol. Cell. Neurosci., 2012 Mar , 49 (375-86).
199. Pubmed Seyler C. et al. TASK1 (K(2P)3.1) K(+) channel inhibition by endothelin-1 is mediated through Rho kinase-dependent phosphorylation. Br. J. Pharmacol., 2012 Mar , 165 (1467-75).
198. Pubmed Shahidullah M. et al. TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity. Am. J. Physiol., Cell Physiol., 2012 Jun , 302 (C1751-61).
197. Pubmed Chubanov V. et al. Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7. , 2012 Jan 13 , ().
196. Pubmed Parajuli S. et al. Pharmacological activation of small conductance calcium-activated potassium channels with naphtho[1,2-d]thiazol-2-ylamine decreases guinea pig detrusor smooth muscle excitability and contractility. J. Pharmacol. Exp. Ther., 2012 Jan , 340 (114-23).
195. Pubmed Aizawa N. et al. Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat. Neurourol. Urodyn., 2012 Jan , 31 (148-55).
194. Pubmed Park S. et al. Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injury. J. Am. Soc. Nephrol., 2012 Feb , 23 (266-80).
193. Pubmed Jin M. et al. Hypotonicity-induced TRPV4 function in renal collecting duct cells: modulation by progressive cross-talk with Ca2+-activated K+ channels. Cell Calcium, 2012 Feb , 51 (131-9).
192. Pubmed Zhang Y. et al. TRPV4 activation in mouse submandibular gland modulates Ca2+ influx and salivation. Am. J. Physiol. Gastrointest. Liver Physiol., 2012 Dec 15 , 303 (G1365-72).
191. Pubmed Bittner S. et al. The TASK1 channel inhibitor A293 shows efficacy in a mouse model of multiple sclerosis. Exp. Neurol., 2012 Dec , 238 (149-55).
190. Pubmed Penton D. et al. Task3 Potassium Channel Gene Invalidation Causes Low Renin and Salt-Sensitive Arterial Hypertension. Endocrinology, 2012 Aug 9 , ().
189. Pubmed Buttigieg J. et al. NOX2 (gp91 phox) is a predominant O2 sensor in a human airway chemoreceptor cell line: biochemical, molecular and electrophysiological evidence. Am. J. Physiol. Lung Cell Mol. Physiol., 2012 Aug 3 , ().
188. Pubmed Afeli S. et al. SK but not IK channels regulate human detrusor smooth muscle spontaneous and nerve-evoked contractions. Am. J. Physiol. Renal Physiol., 2012 Aug 15 , 303 (F559-68).
187. Pubmed Gui L. et al. Role of small conductance calcium-activated potassium channels expressed in PVN in regulating sympathetic nerve activity and arterial blood pressure in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2012 Aug 1 , 303 (R301-10).
186. Pubmed McHugh S. et al. Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X(7) receptor antagonist: a prospective genotyping approach. Br J Clin Pharmacol, 2012 Aug , 74 (376-80).
185. Pubmed Kida N. et al. Importance of transient receptor potential vanilloid 4 (TRPV4) in epidermal barrier function in human skin keratinocytes. Pflugers Arch., 2012 Apr , 463 (715-25).
184. Pubmed Lim M. et al. The role of sphingosine kinase 1/sphingosine-1-phosphate pathway in the myogenic tone of posterior cerebral arteries. PLoS ONE, 2012 , 7 (e35177).
183. Pubmed van der Zanden E. et al. Nicotinic acetylcholine receptor expression and susceptibility to cholinergic immunomodulation in human monocytes of smoking individuals. Neuroimmunomodulation, 2012 , 19 (255-65).
182. Pubmed Girault A. et al. Targeting SKCa channels in cancer: potential new therapeutic approaches. Curr. Med. Chem., 2012 , 19 (697-713).
181. Pubmed Evans A. et al. Ion Channel Regulation by the LKB1-AMPK Signalling Pathway: The Key to Carotid Body Activation by Hypoxia and Metabolic Homeostasis at the Whole Body Level. Adv. Exp. Med. Biol., 2012 , 758 (81-90).
180. Pubmed Weatherall K. et al. Crucial role of a shared extracellular loop in apamin sensitivity and maintenance of pore shape of small-conductance calcium-activated potassium (SK) channels. Proc. Natl. Acad. Sci. U.S.A., 2011 Nov 8 , 108 (18494-9).
179. Pubmed Lamande S. et al. Mutations in TRPV4 cause an inherited arthropathy of hands and feet. Nat. Genet., 2011 Nov , 43 (1142-6).
178. Pubmed Basalingappa K. et al. Characteristics of Kcnn4 channels in the apical membranes of an intestinal epithelial cell line. Am. J. Physiol. Gastrointest. Liver Physiol., 2011 Nov , 301 (G905-11).
177. Pubmed Mergler S. et al. Characterization of transient receptor potential vanilloid channel 4 (TRPV4) in human corneal endothelial cells. Exp. Eye Res., 2011 Nov , 93 (710-9).
176. Pubmed Girault A. et al. New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis. Curr Cancer Drug Targets, 2011 Nov , 11 (1111-25).
175. Pubmed Bobak N. et al. Volume regulation of murine T lymphocytes relies on voltage-dependent and two-pore domain potassium channels. , 2011 May 5 , ().
174. Pubmed Yanni J. et al. Changes in Ion Channel Gene Expression Underlying Heart Failure-induced Sinoatrial Node Dysfunction. , 2011 May 12 , ().
173. Pubmed Ryskamp D. et al. The Polymodal Ion Channel Transient Receptor Potential Vanilloid 4 Modulates Calcium Flux, Spiking Rate, and Apoptosis of Mouse Retinal Ganglion Cells. , 2011 May 11 , 31 (7089-7101).
172. Pubmed Basso M. et al. Polymorphism of CAG motif of SK3 gene is associated with acute oxaliplatin neurotoxicity. Cancer Chemother. Pharmacol., 2011 May , 67 (1179-87).
171. Pubmed Yu T. et al. [Expression and functional role of small conductance Ca(2+)-activated K(+) channels in human atrial myocytes]. Nan Fang Yi Ke Da Xue Xue Bao, 2011 Mar , 31 (490-4).
170. Pubmed Kazmierski W. et al. Novel 4,4-disubstituted piperidine-based C-C chemokine receptor-5 inhibitors with high potency against human immunodeficiency virus-1 and an improved human ether-a-go-go related gene (hERG) profile. J. Med. Chem., 2011 Jun 9 , 54 (3756-67).
169. Pubmed Vincent F. et al. TRPV4 Agonists and Antagonists. , 2011 Jun 14 , ().
168. Pubmed Staudacher K. et al. Carvedilol targets human K2P 3.1 (TASK1) K+ leak channels. Br. J. Pharmacol., 2011 Jul , 163 (1099-110).
167. Pubmed Chen R. et al. Modeling the binding of three toxins to the voltage-gated potassium channel (Kv1.3). Biophys. J., 2011 Dec 7 , 101 (2652-60).
166. Pubmed Yu T. et al. Decreased expression of small-conductance Ca(2+)-activated K(+) channels SK1 and SK2 in human chronic atrial fibrillation. , 2011 Dec 1 , ().
165. Pubmed Prüss H. et al. Potassium channel expression in adult murine neural progenitor cells. Neuroscience, 2011 Apr 28 , 180 (19-29).
164. Pubmed Jin M. et al. Determinants of TRPV4 activity following selective activation by small molecule agonist GSK1016790A. PLoS ONE, 2011 , 6 (e16713).
163. Pubmed Behm D. et al. GSK1562590, a slowly dissociating urotensin-II receptor antagonist, exhibits prolonged pharmacodynamic activity ex vivo. Br. J. Pharmacol., 2010 Sep , 161 (207-28).
162. Pubmed Gao C. et al. Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation. Hippocampus, 2010 Sep , 20 (1072-82).
161. Pubmed Ernest N. et al. Biophysical Properties of Human Medulloblastoma Cells. , 2010 Oct 8 , ().
160. Pubmed Tuteja D. et al. Cardiac small conductance Ca2+-activated K+ channel subunits form heteromultimers via the coiled-coil domains in the C termini of the channels. Circ. Res., 2010 Oct 1 , 107 (851-9).
159. Pubmed Bittner S. et al. From the background to the spotlight: TASK channels in pathological conditions. Brain Pathol., 2010 Nov , 20 (999-1009).
158. Pubmed Kita M. et al. Effects of bladder outlet obstruction on properties of Ca2+-activated K+ channels in rat bladder. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2010 May , 298 (R1310-9).
157. Pubmed Snoek S. et al. Selective alpha7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis. Br. J. Pharmacol., 2010 May , 160 (322-33).
156. Pubmed Samovski D. et al. Gating of the mitochondrial permeability transition pore by long chain fatty acyl analogs in vivo. J. Biol. Chem., 2010 Mar 5 , 285 (6879-90).
155. Pubmed Tang K. et al. Role of ASK1-JNK-p38 Signaling in Kv Channel Remodeling of the Failing Heart: Regulation by Thioredoxin. , 2010 Jun 2 , ().
154. Pubmed Bandulik S. et al. TASK1 and TASK3 potassium channels: determinants of aldosterone secretion and adrenocortical zonation. Horm. Metab. Res., 2010 Jun , 42 (450-7).
153. Pubmed Nogueira E. et al. The role of TASK1 in aldosterone production and its expression in normal adrenal and aldosterone-producing adenomas. Clin. Endocrinol. (Oxf), 2010 Jul , 73 (22-9).
152. Pubmed Noble K. et al. Distribution, expression and functional effects of small conductance Ca-activated potassium (SK) channels in rat myometrium. Cell Calcium, 2010 Jan , 47 (47-54).
151. Pubmed Tan Z. et al. Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR. Circ. Res., 2010 Feb 19 , 106 (536-45).
150. Pubmed Zhao H. et al. Expression of transient receptor potential channels and two-pore potassium channels in subtypes of vagal afferent neurons in rat. Am. J. Physiol. Gastrointest. Liver Physiol., 2010 Feb , 298 (G212-21).
149. Pubmed Mendoza S. et al. TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress. Am. J. Physiol. Heart Circ. Physiol., 2010 Feb , 298 (H466-76).
148. Pubmed Oliveira M. et al. Altered expression and function of small-conductance (SK) Ca(2+)-activated K+ channels in pilocarpine-treated epileptic rats. Brain Res., 2010 Aug 12 , 1348 (187-99).
147. Pubmed Toyoda H. et al. Protein kinase G dynamically modulates TASK1-mediated leak K+ currents in cholinergic neurons of the basal forebrain. J. Neurosci., 2010 Apr 21 , 30 (5677-89).
146. Pubmed Ortega-Sáenz P. et al. Carotid body chemosensory responses in mice deficient of TASK channels. J. Gen. Physiol., 2010 Apr , 135 (379-92).
145. Pubmed Kang Y. et al. Recruitment of masseter motoneurons by the presumed spindle Ia inputs. Prog. Brain Res., 2010 , 187 (163-71).
144. Pubmed Xu X. et al. Functional TRPV4 channels and an absence of capsaicin-evoked currents in freshly-isolated, guinea-pig urothelial cells. Channels (Austin), 2009 May-Jun , 3 (156-60).
143. Pubmed Jacobsen J. et al. Selective cognitive deficits and reduced hippocampal brain-derived neurotrophic factor mRNA expression in small-conductance calcium-activated K+ channel deficient mice. Neuroscience, 2009 Sep 29 , 163 (73-81).
142. Pubmed Hougaard C. et al. Selective activation of the SK1 subtype of human small-conductance Ca2+-activated K+ channels by 4-(2-methoxyphenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 293 in the S5 segment. Mol. Pharmacol., 2009 Sep , 76 (569-78).
141. Pubmed Bittner S. et al. TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system. Brain, 2009 Sep , 132 (2501-16).
140. Pubmed Barbara G. et al. T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids. J. Neurosci., 2009 Oct 21 , 29 (13106-14).
139. Pubmed Corrêa S. et al. Rapid endocytosis provides restricted somatic expression of a K+ channel in central neurons. J. Cell. Sci., 2009 Nov 15 , 122 (4186-94).
138. Pubmed N'Gouemo P. et al. Protein expression of small conductance calcium-activated potassium channels is altered in inferior colliculus neurons of the genetically epilepsy-prone rat. Brain Res., 2009 May 13 , 1270 (107-11).
137. Pubmed Chandler N. et al. Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker. Circulation, 2009 Mar 31 , 119 (1562-75).
136. Pubmed Thomsen M. et al. Deleting the accessory subunit KChIP2 results in loss of I(to,f) and increased I(K,slow) that maintains normal action potential configuration. , 2009 Mar , 6 (370-7).
135. Pubmed Goossens G. et al. Several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB study. Int J Obes (Lond), 2009 Jun , 33 (669-79).
134. Pubmed González J. et al. Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons. Eur. J. Neurosci., 2009 Jul , 30 (57-64).
133. Pubmed Andres M. et al. Depletion of SK1 channel subunits leads to constitutive insulin secretion. FEBS Lett., 2009 Jan 22 , 583 (369-76).
132. Pubmed Meuth S. et al. The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice. Neurobiol. Dis., 2009 Jan , 33 (1-11).
131. Pubmed Guyon A. et al. Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels. J. Neurosci., 2009 Feb 25 , 29 (2528-33).
130. Pubmed Traut M. et al. Identification and characterization of Ca2+-activated K+ channels in granulosa cells of the human ovary. Reprod. Biol. Endocrinol., 2009 , 7 (28).
129. Pubmed Cutz E. et al. The role of NOX2 and "novel oxidases" in airway chemoreceptor O(2) sensing. Adv. Exp. Med. Biol., 2009 , 648 (427-38).
128. Pubmed Meuth S. et al. TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 critically influence T lymphocyte effector functions. J. Biol. Chem., 2008 May 23 , 283 (14559-70).
127. Pubmed Toyoda H. et al. cGMP activates a pH-sensitive leak K+ current in the presumed cholinergic neuron of basal forebrain. J. Neurophysiol., 2008 May , 99 (2126-33).
126. Pubmed Thorneloe K. et al. Small-conductance, Ca(2+) -activated K+ channel 2 is the key functional component of SK channels in mouse urinary bladder. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2008 May , 294 (R1737-43).
125. Pubmed Noguchi T. et al. Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage. J. Biol. Chem., 2008 Mar 21 , 283 (7657-65).
124. Pubmed Marionneau C. et al. Distinct cellular and molecular mechanisms underlie functional remodeling of repolarizing K+ currents with left ventricular hypertrophy. Circ. Res., 2008 Jun 6 , 102 (1406-15).
123. Pubmed Okahira M. et al. Regulation of aquaporin 3 expression by magnesium ion. Eur. J. Pharmacol., 2008 Jun 24 , 588 (26-32).
122. Pubmed Clarke C. et al. The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function. J. Biol. Chem., 2008 Jun 20 , 283 (16985-92).
121. Pubmed Graulich A. et al. Bis-tetrahydroisoquinoline derivatives: AG525E1, a new step in the search for non-quaternary non-peptidic small conductance Ca(2+)-activated K(+) channel blockers. Bioorg. Med. Chem. Lett., 2008 Jun 1 , 18 (3440-5).
120. Pubmed Marionneau C. et al. PPARalpha-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy. J. Mol. Cell. Cardiol., 2008 Jun , 44 (1002-15).
119. Pubmed Heitzmann D. et al. Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis. EMBO J., 2008 Jan 9 , 27 (179-87).
118. Pubmed Pelucchi B. et al. Vertebrate rod photoreceptors express both BK and IK calcium-activated potassium channels, but only BK channels are involved in receptor potential regulation. J. Neurosci. Res., 2008 Jan , 86 (194-201).
117. Pubmed Palmer M. et al. Apical SK potassium channels and Ca2+-dependent anion secretion in endometrial epithelial cells. J. Physiol. (Lond.), 2008 Feb 1 , 586 (717-26).
116. Pubmed Meuth S. et al. Altered neuronal expression of TASK1 and TASK3 potassium channels in rodent and human autoimmune CNS inflammation. Neurosci. Lett., 2008 Dec 3 , 446 (133-8).
115. Pubmed Matsuyama H. et al. Evidence that TASK1 channels contribute to the background current in AH/type II neurons of the guinea-pig intestine. Neuroscience, 2008 Aug 26 , 155 (738-50).
114. Pubmed Peter B. et al. Role of sphingosine-1-phosphate phosphohydrolase 1 in the regulation of resistance artery tone. Circ. Res., 2008 Aug 1 , 103 (315-24).
113. Pubmed Thorneloe K. et al. N-((1S)-1-{[4-((2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a novel and potent transient receptor potential vanilloid 4 channel agonist induces urinar J. Pharmacol. Exp. Ther., 2008 Aug , 326 (432-42).
112. Pubmed Willette R. et al. Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2. J. Pharmacol. Exp. Ther., 2008 Aug , 326 (443-52).
111. Pubmed Inoue M. et al. Inhibition of TASK1-like channels by muscarinic receptor stimulation in rat adrenal medullary cells. J. Neurochem., 2008 Aug , 106 (1804-14).
110. Pubmed Ellis L. et al. Differential distribution of SK channel subtypes in the brain of the weakly electric fish Apteronotus leptorhynchus. J. Comp. Neurol., 2008 Apr 20 , 507 (1964-78).
109. Pubmed Veale E. et al. Identification of a region in the TASK3 two pore domain potassium channel that is critical for its blockade by methanandamide. Br. J. Pharmacol., 2007 Nov , 152 (778-86).
108. Pubmed Kajimoto T. et al. Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons. Mol. Cell. Biol., 2007 May , 27 (3429-40).
107. Pubmed Yazdi H. et al. The role of small-conductance Ca2+-activated K+ channels in the modulation of 4-aminopyridine-induced burst firing in rat cerebellar Purkinje cells. Brain Res., 2007 Jul 2 , 1156 (59-66).
106. Pubmed Gaborit N. et al. Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart. J. Physiol. (Lond.), 2007 Jul 15 , 582 (675-93).
105. Pubmed Seutin V. et al. SK channels are on the move. Br. J. Pharmacol., 2007 Jul , 151 (568-70).
104. Pubmed Hougaard C. et al. Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+-activated K+ channels. Br. J. Pharmacol., 2007 Jul , 151 (655-65).
103. Pubmed Nolting A. et al. An amino acid outside the pore region influences apamin sensitivity in small conductance Ca2+-activated K+ channels. J. Biol. Chem., 2007 Feb 9 , 282 (3478-86).
102. Pubmed Ota M. et al. Risperidone reduces mRNA expression levels of Sulfonylurea Receptor 1 and TASK1 in PC12 cells. Neurosci. Lett., 2007 Feb 2 , 412 (254-8).
101. Pubmed Ceroni L. et al. Calcium-activated potassium channel and connexin expression in small mesenteric arteries from eNOS-deficient (eNOS-/-) and eNOS-expressing (eNOS+/+) mice. Eur. J. Pharmacol., 2007 Apr 10 , 560 (193-200).
100. Pubmed Wulff H. et al. Modulators of small- and intermediate-conductance calcium-activated potassium channels and their therapeutic indications. Curr. Med. Chem., 2007 , 14 (1437-57).
99. Pubmed Meuth S. et al. Membrane resting potential of thalamocortical relay neurons is shaped by the interaction among TASK3 and HCN2 channels. J. Neurophysiol., 2006 Sep , 96 (1517-29).
98. Pubmed Brosh I. et al. Learning-induced reversal of the effect of noradrenalin on the postburst AHP. J. Neurophysiol., 2006 Oct , 96 (1728-33).
97. Pubmed Wilson S. et al. Expression of intermediate-conductance, Ca2+-activated K+ channel (KCNN4) in H441 human distal airway epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol., 2006 Nov , 291 (L957-65).
96. Pubmed Strøbaek D. et al. Inhibitory gating modulation of small conductance Ca2+-activated K+ channels by the synthetic compound (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphtylamine (NS8593) reduces afterhyperpolarizing current in hippocampal CA1 neurons. Mol. Pharmacol., 2006 Nov , 70 (1771-82).
95. Pubmed Peitersen T. et al. Subtype-specific, bi-component inhibition of SK channels by low internal pH. Biochem. Biophys. Res. Commun., 2006 May 12 , 343 (943-9).
94. Pubmed Imoto K. et al. Impact of mitochondrial reactive oxygen species and apoptosis signal-regulating kinase 1 on insulin signaling. Diabetes, 2006 May , 55 (1197-204).
93. Pubmed Kato M. et al. The SK channel blocker apamin inhibits slow afterhyperpolarization currents in rat gonadotropin-releasing hormone neurones. J. Physiol. (Lond.), 2006 Jul 15 , 574 (431-42).
92. Pubmed Hilgers R. et al. Regional heterogeneity in acetylcholine-induced relaxation in rat vascular bed: role of calcium-activated K+ channels. Am. J. Physiol. Heart Circ. Physiol., 2006 Jul , 291 (H216-22).
91. Pubmed Bai X. et al. TASK channel expression in human placenta and cytotrophoblast cells. J. Soc. Gynecol. Investig., 2006 Jan , 13 (30-9).
90. Pubmed Hammond R. et al. Small-conductance Ca2+-activated K+ channel type 2 (SK2) modulates hippocampal learning, memory, and synaptic plasticity. J. Neurosci., 2006 Feb 8 , 26 (1844-53).
89. Pubmed Kiyoshi H. et al. Molecular and electrophysiological characteristics of K+ conductance sensitive to acidic pH in aortic smooth muscle cells of WKY and SHR. Am. J. Physiol. Heart Circ. Physiol., 2006 Dec , 291 (H2723-34).
88. Pubmed Weaver A. et al. Expression and function of calcium-activated potassium channels in human glioma cells. Glia, 2006 Aug 15 , 54 (223-33).
87. Pubmed Wareing M. et al. Expression and function of potassium channels in the human placental vasculature. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2006 Aug , 291 (R437-46).
86. Pubmed Zhou C. et al. Angiotensin II and stretch activate NADPH oxidase to destabilize cardiac Kv4.3 channel mRNA. Circ. Res., 2006 Apr 28 , 98 (1040-7).
85. Pubmed Frei E. et al. Interactions of N-terminal and C-terminal parts of the small conductance Ca2+ activated K+ channel, hSK3. Cell. Physiol. Biochem., 2006 , 18 (165-76).
84. Pubmed Aras M. et al. Obligatory role of ASK1 in the apoptotic surge of K+ currents. Neurosci. Lett., 2005 Oct 28 , 387 (136-40).
83. Pubmed Keating D. et al. Oxygen-sensing pathway for SK channels in the ovine adrenal medulla. Clin. Exp. Pharmacol. Physiol., 2005 Oct , 32 (882-7).
82. Pubmed Heffron D. et al. Differential localization of MAPK-activated protein kinases RSK1 and MSK1 in mouse brain. Brain Res. Mol. Brain Res., 2005 May 20 , 136 (134-41).
81. Pubmed Chuang C. et al. A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling. Genes Dev., 2005 Jan 15 , 19 (270-81).
80. Pubmed Mouhat S. et al. K+ channel types targeted by synthetic OSK1, a toxin from Orthochirus scrobiculosus scorpion venom. Biochem. J., 2005 Jan 1 , 385 (95-104).
79. Pubmed O'Connell A. et al. Selectivity and interactions of Ba2+ and Cs+ with wild-type and mutant TASK1 K+ channels expressed in Xenopus oocytes. J. Physiol. (Lond.), 2005 Feb 1 , 562 (687-96).
78. Pubmed Bai X. et al. Localization of TASK and TREK, two-pore domain K+ channels, in human cytotrophoblast cells. J. Soc. Gynecol. Investig., 2005 Feb , 12 (77-83).
77. Pubmed Lappin S. et al. Activation of SK channels inhibits epileptiform bursting in hippocampal CA3 neurons. Brain Res., 2005 Dec 14 , 1065 (37-46).
76. Pubmed Tuteja D. et al. Differential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytes. Am. J. Physiol. Heart Circ. Physiol., 2005 Dec , 289 (H2714-23).
75. Pubmed Lopes C. et al. PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels. J. Physiol. (Lond.), 2005 Apr 1 , 564 (117-29).
74. Pubmed Bai X. et al. Expression of TASK and TREK, two-pore domain K+ channels, in human myometrium. Reproduction, 2005 Apr , 129 (525-30).
73. Pubmed Mongan L. et al. The distribution of small and intermediate conductance calcium-activated potassium channels in the rat sensory nervous system. Neuroscience, 2005 , 131 (161-75).
72. Pubmed Holter J. et al. A TASK3 channel (KCNK9) mutation in a genetic model of absence epilepsy. J. Mol. Neurosci., 2005 , 25 (37-51).
71. Pubmed Kemp P. et al. Regulation of recombinant human brain tandem P domain K+ channels by hypoxia: a role for O2 in the control of neuronal excitability? J. Cell. Mol. Med., 2004 Jan-Mar , 8 (38-44).
70. Pubmed Begenisich T. et al. Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4. J. Biol. Chem., 2004 Nov 12 , 279 (47681-7).
69. Pubmed Scuvée-Moreau J. et al. Electrophysiological characterization of the SK channel blockers methyl-laudanosine and methyl-noscapine in cell lines and rat brain slices. Br. J. Pharmacol., 2004 Nov , 143 (753-64).
68. Pubmed D'Hoedt D. et al. Domain analysis of the calcium-activated potassium channel SK1 from rat brain. Functional expression and toxin sensitivity. J. Biol. Chem., 2004 Mar 26 , 279 (12088-92).
67. Pubmed Jäger H. et al. Characterization of the outer pore region of the apamin-sensitive Ca2+-activated K+ channel rSK2. Toxicon, 2004 Jun 15 , 43 (951-60).
66. Pubmed Chen M. et al. Small and intermediate conductance Ca(2+)-activated K+ channels confer distinctive patterns of distribution in human tissues and differential cellular localisation in the colon and corpus cavernosum. Naunyn Schmiedebergs Arch. Pharmacol., 2004 Jun , 369 (602-15).
65. Pubmed Vennekamp J. et al. Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators. Mol. Pharmacol., 2004 Jun , 65 (1364-74).
64. Pubmed Blank T. et al. Small conductance Ca2+-activated K+ channels as targets of CNS drug development. , 2004 Jun , 3 (161-7).
63. Pubmed Sailer C. et al. Comparative immunohistochemical distribution of three small-conductance Ca2+-activated potassium channel subunits, SK1, SK2, and SK3 in mouse brain. Mol. Cell. Neurosci., 2004 Jul , 26 (458-69).
62. Pubmed Monaghan A. et al. The SK3 subunit of small conductance Ca2+-activated K+ channels interacts with both SK1 and SK2 subunits in a heterologous expression system. J. Biol. Chem., 2004 Jan 9 , 279 (1003-9).
61. Pubmed Kolski-Andreaco A. et al. SK3-1C, a dominant-negative suppressor of SKCa and IKCa channels. J. Biol. Chem., 2004 Feb 20 , 279 (6893-904).
60. Pubmed Takeda K. et al. Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation. EMBO Rep., 2004 Feb , 5 (161-6).
59. Pubmed Grunnet M. et al. 5-HT1A receptors modulate small-conductance Ca2+-activated K+ channels. J. Neurosci. Res., 2004 Dec 15 , 78 (845-54).
58. Pubmed Villalobos C. et al. SKCa channels mediate the medium but not the slow calcium-activated afterhyperpolarization in cortical neurons. J. Neurosci., 2004 Apr 7 , 24 (3537-42).
57. Pubmed Lawrence C. et al. Evidence of a new role for the high-osmolarity glycerol mitogen-activated protein kinase pathway in yeast: regulating adaptation to citric acid stress. Mol. Cell. Biol., 2004 Apr , 24 (3307-23).
56. Pubmed Herrera G. et al. Urinary bladder instability induced by selective suppression of the murine small conductance calcium-activated potassium (SK3) channel. J. Physiol. (Lond.), 2003 Sep 15 , 551 (893-903).
55. Pubmed Benton D. et al. Small conductance Ca2+-activated K+ channels formed by the expression of rat SK1 and SK2 genes in HEK 293 cells. J. Physiol. (Lond.), 2003 Nov 15 , 553 (13-9).
54. Pubmed Bernard K. et al. Modulation of calcium-dependent chloride secretion by basolateral SK4-like channels in a human bronchial cell line. J. Membr. Biol., 2003 Nov 1 , 196 (15-31).
53. Pubmed Fletcher S. et al. False interaction of syntaxin 1A with a Ca(2+)-activated K(+) channel revealed by co-immunoprecipitation and pull-down assays: implications for identification of protein-protein interactions. Neuropharmacology, 2003 May , 44 (817-27).
52. Pubmed Terstappen G. et al. The antidepressant fluoxetine blocks the human small conductance calcium-activated potassium channels SK1, SK2 and SK3. Neurosci. Lett., 2003 Jul 31 , 346 (85-8).
51. Pubmed Meuth S. et al. Contribution of TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 channels to the control of activity modes in thalamocortical neurons. J. Neurosci., 2003 Jul 23 , 23 (6460-9).
50. Pubmed Zhang Q. et al. Biphasic activation of apoptosis signal-regulating kinase 1-stress-activated protein kinase 1-c-Jun N-terminal protein kinase pathway is selectively mediated by Ca2+-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors involving oxidat Neurosci. Lett., 2003 Jan 30 , 337 (51-5).
49. Pubmed Wang J. et al. IK channels are involved in the regulatory volume decrease in human epithelial cells. Am. J. Physiol., Cell Physiol., 2003 Jan , 284 (C77-84).
48. Pubmed Castle N. et al. Maurotoxin: a potent inhibitor of intermediate conductance Ca2+-activated potassium channels. Mol. Pharmacol., 2003 Feb , 63 (409-18).
47. Pubmed Obermair G. et al. The small conductance Ca2+-activated K+ channel SK3 is localized in nerve terminals of excitatory synapses of cultured mouse hippocampal neurons. Eur. J. Neurosci., 2003 Feb , 17 (721-31).
46. Pubmed Hashiguchi-Ikeda M. et al. Halothane inhibits an intermediate conductance Ca2+-activated K+ channel by acting at the extracellular side of the ionic pore. Anesthesiology, 2003 Dec , 99 (1340-5).
45. Pubmed Tamarina N. et al. Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses. Diabetes, 2003 Aug , 52 (2000-6).
44. Pubmed Fujita A. et al. Expression of the small conductance Ca2+-activated K+ channel, SK3, in the olfactory ensheathing glial cells of rat brain. Cell Tissue Res., 2003 Aug , 313 (187-93).
43. Pubmed Liégeois J. et al. Modulation of small conductance calcium-activated potassium (SK) channels: a new challenge in medicinal chemistry. Curr. Med. Chem., 2003 Apr , 10 (625-47).
42. Pubmed Patko T. et al. Modulation of the voltage-gated sodium- and calcium-dependent potassium channels in rat vestibular and facial nuclei after unilateral labyrinthectomy and facial nerve transsection: an in situ hybridization study. Neuroscience, 2003 , 117 (265-80).
41. Pubmed Lubec G. et al. RNA microarray analysis of channels and transporters in normal and fetal Down syndrome (trisomy 21) brain. J. Neural Transm. Suppl., 2003 , (215-24).
40. Pubmed Pedarzani P. et al. Tamapin, a venom peptide from the Indian red scorpion (Mesobuthus tamulus) that targets small conductance Ca2+-activated K+ channels and afterhyperpolarization currents in central neurons. J. Biol. Chem., 2002 Nov 29 , 277 (46101-9).
39. Pubmed Sailer C. et al. Regional differences in distribution and functional expression of small-conductance Ca2+-activated K+ channels in rat brain. J. Neurosci., 2002 Nov 15 , 22 (9698-707).
38. Pubmed Dale T. et al. Partial apamin sensitivity of human small conductance Ca2+-activated K+ channels stably expressed in Chinese hamster ovary cells. Naunyn Schmiedebergs Arch. Pharmacol., 2002 Nov , 366 (470-7).
37. Pubmed Bosch M. et al. Distribution, neuronal colocalization, and 17beta-E2 modulation of small conductance calcium-activated K(+) channel (SK3) mRNA in the guinea pig brain. Endocrinology, 2002 Mar , 143 (1097-107).
36. Pubmed Burnham M. et al. Characterization of an apamin-sensitive small-conductance Ca(2+)-activated K(+) channel in porcine coronary artery endothelium: relevance to EDHF. Br. J. Pharmacol., 2002 Mar , 135 (1133-43).
35. Pubmed Carignani C. et al. Pharmacological and molecular characterisation of SK3 channels in the TE671 human medulloblastoma cell line. Brain Res., 2002 Jun 7 , 939 (11-8).
34. Pubmed Drici M. et al. Mice display sex differences in halothane-induced polymorphic ventricular tachycardia. Circulation, 2002 Jul 23 , 106 (497-503).
33. Pubmed Boettger M. et al. Calcium-activated potassium channel SK1- and IK1-like immunoreactivity in injured human sensory neurones and its regulation by neurotrophic factors. Brain, 2002 Feb , 125 (252-63).
32. Pubmed Protasi F. et al. Multiple regions of RyR1 mediate functional and structural interactions with alpha(1S)-dihydropyridine receptors in skeletal muscle. Biophys. J., 2002 Dec , 83 (3230-44).
31. Pubmed Cui M. et al. Brownian dynamics simulations of the recognition of the scorpion toxin P05 with the small-conductance calcium-activated potassium channels. J. Mol. Biol., 2002 Apr 26 , 318 (417-28).
30. Pubmed Hosseini R. et al. SK3 is an important component of K(+) channels mediating the afterhyperpolarization in cultured rat SCG neurones. J. Physiol. (Lond.), 2001 Sep 1 , 535 (323-34).
29. Pubmed Finlayson K. et al. Characterisation of [(125)I]-apamin binding sites in rat brain membranes with HE293 cells transfected with SK channel subtypes. Neuropharmacology, 2001 Sep , 41 (341-50).
28. Pubmed Bowden S. et al. Somatic colocalization of rat SK1 and D class (Ca(v)1.2) L-type calcium channels in rat CA1 hippocampal pyramidal neurons. J. Neurosci., 2001 Oct 15 , 21 (RC175).
27. Pubmed Ro S. et al. Molecular properties of small-conductance Ca2+-activated K+ channels expressed in murine colonic smooth muscle. Am. J. Physiol. Gastrointest. Liver Physiol., 2001 Oct , 281 (G964-73).
26. Pubmed Fujita A. et al. Expression of Ca(2+)-activated K(+) channels, SK3, in the interstitial cells of Cajal in the gastrointestinal tract. Am. J. Physiol., Cell Physiol., 2001 Nov , 281 (C1727-33).
25. Pubmed Korolkova Y. et al. An ERG channel inhibitor from the scorpion Buthus eupeus. J. Biol. Chem., 2001 Mar 30 , 276 (9868-76).
24. Pubmed Shmukler B. et al. Structure and complex transcription pattern of the mouse SK1 K(Ca) channel gene, KCNN1. Biochim. Biophys. Acta, 2001 Mar 19 , 1518 (36-46).
23. Pubmed Zhang B. et al. Calmodulin binding to the C-terminus of the small-conductance Ca2+-activated K+ channel hSK1 is affected by alternative splicing. Biochemistry, 2001 Mar 13 , 40 (3189-95).
22. Pubmed Kim D. et al. TASK-5, a new member of the tandem-pore K(+) channel family. Biochem. Biophys. Res. Commun., 2001 Jun 22 , 284 (923-30).
21. Pubmed Gerlach A. et al. ATP-dependent activation of the intermediate conductance, Ca2+-activated K+ channel, hIK1, is conferred by a C-terminal domain. J. Biol. Chem., 2001 Jun 15 , 276 (10963-70).
20. Pubmed Hartness M. et al. Combined antisense and pharmacological approaches implicate hTASK as an airway O(2) sensing K(+) channel. J. Biol. Chem., 2001 Jul 13 , 276 (26499-508).
19. Pubmed Grunnet M. et al. Apamin interacts with all subtypes of cloned small-conductance Ca2+-activated K+ channels. Pflugers Arch., 2001 Jan , 441 (544-50).
18. Pubmed Shah M. et al. Clotrimazole analogues: effective blockers of the slow afterhyperpolarization in cultured rat hippocampal pyramidal neurones. Br. J. Pharmacol., 2001 Feb , 132 (889-98).
17. Pubmed Lewis A. et al. Recombinant hTASK1 is an O(2)-sensitive K(+) channel. Biochem. Biophys. Res. Commun., 2001 Aug 3 , 285 (1290-4).
16. Pubmed Gerlach A. et al. ATP-dependent activation of the intermediate conductance, Ca2+-activated K+ channel, hIK1, is conferred by a C-terminal domain. J. Biol. Chem., 2001 Apr 6 , 276 (10963-70).
15. Pubmed Roncarati R. et al. Presynaptic localization of the small conductance calcium-activated potassium channel SK3 at the neuromuscular junction. Neuroscience, 2001 , 104 (253-62).
14. Pubmed Sun G. et al. Genomic organization and promoter analysis of human KCNN3 gene. J. Hum. Genet., 2001 , 46 (463-70).
13. Pubmed Pedarzani P. et al. Molecular determinants of Ca2+-dependent K+ channel function in rat dorsal vagal neurones. J. Physiol. (Lond.), 2000 Sep 1 , 527 Pt 2 (283-90).
12. Pubmed Stocker M. et al. Differential distribution of three Ca(2+)-activated K(+) channel subunits, SK1, SK2, and SK3, in the adult rat central nervous system. Mol. Cell. Neurosci., 2000 May , 15 (476-93).
11. Pubmed Strøbaek D. et al. Pharmacological characterization of small-conductance Ca(2+)-activated K(+) channels stably expressed in HEK 293 cells. Br. J. Pharmacol., 2000 Mar , 129 (991-9).
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