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All references automaticaly matched for Nav1


613. Pubmed Aydar E. et al. Sigma-1 receptors modulate neonatal Nav1.5 ion channels in breast cancer cell lines. Eur. Biophys. J., 2016 May 9 , ().
612. Pubmed Yang J. et al. FGF13 modulates the gating properties of the cardiac sodium channel Nav1.5 in an isoform-specific manner. Channels (Austin), 2016 May 31 , (1-11).
611. Pubmed Hirano-Iwata A. et al. Reconstitution of Human Ion Channels into Solvent-free Lipid Bilayers Enhanced by Centrifugal Forces. Biophys. J., 2016 May 24 , 110 (2207-15).
610. Pubmed Zeng H. et al. Use of FDSS/μCell imaging platform for preclinical cardiac electrophysiology safety screening of compounds in human induced pluripotent stem cell-derived cardiomyocytes. J Pharmacol Toxicol Methods, 2016 May 21 , ().
609. Pubmed Rosberg M. et al. Progression of motor axon dysfunction and ectopic Nav1.8 expression in a mouse model of Charcot-Marie-Tooth disease 1B. Neurobiol. Dis., 2016 May 20 , 93 (201-214).
608. Pubmed Ali S. et al. Identification of Amino Acid Residues in Fibroblast Growth Factor 14 (FGF14) Required for Structure-Function Interactions with Voltage-gated Sodium Channel Nav1.6. J. Biol. Chem., 2016 May 20 , 291 (11268-84).
607. Pubmed Mulcahy J. et al. Synthesis of the Paralytic Shellfish Poisons (+)-Gonyautoxin 2, (+)-Gonyautoxin 3, and (+)-11,11-Dihydroxysaxitoxin. J. Am. Chem. Soc., 2016 May 11 , 138 (5994-6001).
606. Pubmed Schilling J. et al. Electrophysiology and metabolism of caveolin-3-overexpressing mice. Basic Res. Cardiol., 2016 May , 111 (28).
605. Pubmed Cheng L. et al. Effects of Fluvastatin on Characteristics of Stellate Ganglion Neurons in a Rabbit Model of Myocardial Ischemia. Chin. Med. J., 2016 May , 129 (549-56).
604. Pubmed Gupta B. et al. Antinociceptive properties of shikonin: in vitro and in vivo studies. Can. J. Physiol. Pharmacol., 2016 Mar 6 , (1-9).
603. Pubmed Patel D. et al. Computational Study of Binding of μ-Conotoxin GIIIA to Bacterial Sodium Channels NaVAb and NaVRh. Biochemistry, 2016 Mar 29 , 55 (1929-38).
602. Pubmed Tao H. et al. Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels. Toxicon, 2016 Mar 1 , 111 (13-21).
601. Pubmed Rogers M. et al. Characterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp Screening. Assay Drug Dev Technol, 2016 Mar , 14 (109-30).
600. Pubmed Chambers C. et al. High-Throughput Screening of NaV1.7 Modulators Using a Giga-Seal Automated Patch Clamp Instrument. Assay Drug Dev Technol, 2016 Mar , 14 (93-108).
599. Pubmed Henriques S. et al. Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes is a Prerequisite for its Inhibition of Human Voltage-gated Sodium Channel NaV1.7. J. Biol. Chem., 2016 Jun 16 , ().
598. Pubmed Xu J. et al. Peimine, a main active ingredient of Fritillaria, exhibits anti-inflammatory and pain suppression properties at the cellular level. Fitoterapia, 2016 Jun , 111 (1-6).
597. Pubmed Du Y. et al. β1-Adrenergic blocker bisoprolol reverses down-regulated ion channels in sinoatrial node of heart failure rats. J. Physiol. Biochem., 2016 Jun , 72 (293-302).
596. Pubmed Arias H. et al. Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content. Int. J. Biochem. Cell Biol., 2016 Jul , 76 (19-30).
595. Pubmed Zaklyazminskaya E. et al. The role of mutations in the SCN5A gene in cardiomyopathies. Biochim. Biophys. Acta, 2016 Jul , 1863 (1799-805).
594. Pubmed Sottas V. et al. Negative-dominance phenomenon with genetic variants of the cardiac sodium channel Nav1.5. Biochim. Biophys. Acta, 2016 Jul , 1863 (1791-8).
593. Pubmed Green B. et al. Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin μO§-GVIIJ. J. Biol. Chem., 2016 Jan 27 , ().
592. Pubmed Cui H. et al. Catalytic asymmetric hetero-Diels-Alder reactions of enones with isatins to access functionalized spirooxindole tetrahydropyrans: scope, derivatization, and discovery of bioactives. Org. Biomol. Chem., 2016 Jan 27 , 14 (1777-83).
591. Pubmed Wang H. et al. A novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias. J. Mol. Cell. Cardiol., 2016 Jan 19 , 92 (52-62).
590. Pubmed Tarvin R. et al. Convergent Substitutions in a Sodium Channel Suggest Multiple Origins of Toxin Resistance in Poison Frogs. Mol. Biol. Evol., 2016 Jan 18 , ().
589. Pubmed He B. et al. Effects of the β1 auxiliary subunit on modification of Rat Na(v)1.6 sodium channels expressed in HEK293 cells by the pyrethroid insecticides tefluthrin and deltamethrin. Toxicol. Appl. Pharmacol., 2016 Jan 15 , 291 (58-69).
588. Pubmed Habbout K. et al. A recessive Nav1.4 mutation underlies congenital myasthenic syndrome with periodic paralysis. Neurology, 2016 Jan 12 , 86 (161-9).
587. Pubmed Mohammed F. et al. Blockade of voltage-gated sodium channels inhibits invasion of endocrine-resistant breast cancer cells. Int. J. Oncol., 2016 Jan , 48 (73-83).
586. Pubmed Horvath G. et al. Secondary neurotransmitter deficiencies in epilepsy caused by voltage-gated sodium channelopathies: A potential treatment target? Mol. Genet. Metab., 2016 Jan , 117 (42-8).
585. Pubmed Stueber T. et al. Quaternary Lidocaine Derivative QX-314 Activates and Permeates Human TRPV1 and TRPA1 to Produce Inhibition of Sodium Channels and Cytotoxicity. Anesthesiology, 2016 Feb 9 , ().
584. Pubmed Han C. et al. Sodium channel Nav1.8: Emerging links to human disease. Neurology, 2016 Feb 2 , 86 (473-83).
583. Pubmed Roostaei T. et al. Channelopathy-related SCN10A gene variants predict cerebellar dysfunction in multiple sclerosis. Neurology, 2016 Feb 2 , 86 (410-7).
582. Pubmed Murray J. et al. Single Residue Substitutions That Confer NaV Subtype Selectivity in the NaV1.7 Inhibitory Peptide GpTx-1. J. Med. Chem., 2016 Feb 18 , ().
581. Pubmed Benned-Jensen T. et al. Live Imaging of Kv7.2/7.3 Cell Surface Dynamics at the Axon Initial Segment: High Steady-State Stability and Calpain-Dependent Excitotoxic Downregulation Revealed. J. Neurosci., 2016 Feb 17 , 36 (2261-6).
580. Pubmed Kim K. et al. Maturation of NaV and KV Channel Topographies in the Auditory Nerve Spike Initiator before and after Developmental Onset of Hearing Function. J. Neurosci., 2016 Feb 17 , 36 (2111-8).
579. Pubmed Poulet C. et al. Altered physiological functions and ion currents in atrial fibroblasts from patients with chronic atrial fibrillation. Physiol Rep, 2016 Feb , 4 ().
578. Pubmed Ye P. et al. Functional up-regulation of Nav1.8 sodium channel on dorsal root ganglia neurons contributes to the induction of scorpion sting pain. Acta Biochim. Biophys. Sin. (Shanghai), 2016 Feb , 48 (132-44).
577. Pubmed Murenzi E. et al. Evaluation of microtransplantation of rat brain neurolemma into Xenopus laevis oocytes as a technique to study the effect of neurotoxicants on endogenous voltage-sensitive ion channels. Neurotoxicology, 2016 Apr 7 , ().
576. Pubmed Crumb W. et al. An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel. J Pharmacol Toxicol Methods, 2016 Apr 6 , ().
575. Pubmed Branch S. et al. Dopaminergic Neurons Exhibit an Age-Dependent Decline in Electrophysiological Parameters in the MitoPark Mouse Model of Parkinson's Disease. J. Neurosci., 2016 Apr 6 , 36 (4026-37).
574. Pubmed Shcherbatko A. et al. Engineering Highly Potent and Selective Microproteins Against Nav1.7 Sodium Channel for Treatment of Pain. J. Biol. Chem., 2016 Apr 22 , ().
573. Pubmed Frost J. et al. Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain. J. Med. Chem., 2016 Apr 14 , 59 (3373-91).
572. Pubmed Nassal D. et al. Myocardial KChIP2 Expression in Guinea Pig Resolves an Expanded Electrophysiologic Role. PLoS ONE, 2016 , 11 (e0146561).
571. Pubmed Zhang H. et al. Optical electrophysiology for probing function and pharmacology of voltage-gated ion channels. Elife, 2016 , 5 ().
570. Pubmed Lazcano-Pérez F. et al. Activity of Palythoa caribaeorum Venom on Voltage-Gated Ion Channels in Mammalian Superior Cervical Ganglion Neurons. Toxins (Basel), 2016 , 8 ().
569. Pubmed Kubanek J. et al. Ultrasound modulates ion channel currents. Sci Rep, 2016 , 6 (24170).
568. Pubmed Choi J. et al. α1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current. PLoS ONE, 2016 , 11 (e0152355).
567. Pubmed Alshammari M. et al. Improved Methods for Fluorescence Microscopy Detection of Macromolecules at the Axon Initial Segment. Front Cell Neurosci, 2016 , 10 (5).
566. Pubmed Leo-Macias A. et al. Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc. Nat Commun, 2016 , 7 (10342).
565. Pubmed Wang X. et al. Characterization of Specific Roles of Sodium Channel Subtypes in Regional Anesthesia. Reg Anesth Pain Med, 2015 Sep-Oct , 40 (599-604).
564. Pubmed Eberhardt E. et al. Pattern of Functional TTX-Resistant Sodium Channels Reveals a Developmental Stage of Human iPSC- and ESC-Derived Nociceptors. Stem Cell Reports, 2015 Sep 8 , 5 (305-13).
563. Pubmed Ji R. et al. Neuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms? Pulm Pharmacol Ther, 2015 Sep 6 , ().
562. Pubmed Salas M. et al. Tetrodotoxin suppresses thermal hyperalgesia and mechanical allodynia in a rat full thickness thermal injury pain model. Neurosci. Lett., 2015 Sep 28 , 607 (108-113).
561. Pubmed Nutter T. et al. A delayed chronic pain like condition with decreased Kv channel activity in a rat model of Gulf War Illness pain syndrome. Neurotoxicology, 2015 Sep 26 , 51 (67-79).
560. Pubmed Remacle A. et al. Matrix Metalloproteinase (MMP) Proteolysis of the Extracellular Loop of Voltage-gated Sodium Channels and Potential Alterations in Pain Signaling. J. Biol. Chem., 2015 Sep 18 , 290 (22939-44).
559. Pubmed Neshatian L. et al. Ranolazine inhibits voltage-gated mechanosensitive sodium channels in human colon circular smooth muscle cells. Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Sep 15 , 309 (G506-12).
558. Pubmed Kurowski P. et al. Muscarinic receptor control of pyramidal neuron membrane potential in the medial prefrontal cortex (mPFC) in rats. Neuroscience, 2015 Sep 10 , 303 (474-88).
557. Pubmed Dib-Hajj S. et al. NaV1.9: a sodium channel linked to human pain. Nat. Rev. Neurosci., 2015 Sep , 16 (511-9).
556. Pubmed Aktas C. et al. In vitro effects of phenytoin and DAPT on MDA-MB-231 breast cancer cells. Acta Biochim. Biophys. Sin. (Shanghai), 2015 Sep , 47 (680-6).
555. Pubmed Li G. et al. Positive shift of Nav1.8 current inactivation curve in injured neurons causes neuropathic pain following chronic constriction injury. Mol Med Rep, 2015 Sep , 12 (3583-90).
554. Pubmed Namer B. et al. Specific changes in conduction velocity recovery cycles of single nociceptors in a patient with erythromelalgia with the I848T gain-of-function mutation of Nav1.7. Pain, 2015 Sep , 156 (1637-46).
553. Pubmed Estacion M. et al. Ca2+ toxicity due to reverse Na+/Ca2+ exchange contributes to degeneration of neurites of DRG neurons induced by a neuropathy-associated Nav1.7 mutation. J. Neurophysiol., 2015 Sep , 114 (1554-64).
552. Pubmed Musa H. et al. SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia. Proc. Natl. Acad. Sci. U.S.A., 2015 Oct 6 , 112 (12528-33).
551. Pubmed Endo R. et al. Carvedilol Suppresses Apoptosis and Ion Channel Remodelling of HL-1 Cardiac Myocytes Expressing E334K cMyBPC. Drug Res (Stuttg), 2015 Oct 19 , ().
550. Pubmed Hao W. et al. Design, synthesis and structure-activity relationship of indoxacarb analogs as voltage-gated sodium channel blocker. Bioorg. Med. Chem. Lett., 2015 Oct 15 , 25 (4576-9).
549. Pubmed Patel R. et al. Ionic Mechanisms of Spinal Neuronal Cold Hypersensitivity in Ciguatera. Eur. J. Neurosci., 2015 Oct 10 , ().
548. Pubmed Klint J. et al. Rational engineering defines a molecular switch that is essential for activity of spider-venom peptides against the analgesics target NaV1.7. Mol. Pharmacol., 2015 Oct 1 , ().
547. Pubmed Nicole S. et al. Skeletal muscle sodium channelopathies. Curr. Opin. Neurol., 2015 Oct , 28 (508-514xs).
546. Pubmed Detta N. et al. The multi-faceted aspects of the complex cardiac Nav1.5 protein in membrane function and pathophysiology. Biochim. Biophys. Acta, 2015 Oct , 1854 (1502-9).
545. Pubmed Torbergsen T. et al. Painful cramps and giant myotonic discharges in a family with the Nav1.4-G1306A mutation. Muscle Nerve, 2015 Oct , 52 (680-3).
544. Pubmed Murray J. et al. Sustained inhibition of the NaV1.7 sodium channel by engineered dimers of the domain II binding peptide GpTx-1. Bioorg. Med. Chem. Lett., 2015 Nov 1 , 25 (4866-71).
543. Pubmed Zheng G. et al. Chronic stress and peripheral pain: Evidence for distinct, region-specific changes in visceral and somatosensory pain regulatory pathways. Exp. Neurol., 2015 Nov , 273 (301-11).
542. Pubmed Gawali V. et al. Mechanism of Modification, by Lidocaine, of Fast and Slow Recovery from Inactivation of Voltage-Gated Na⁺ Channels. Mol. Pharmacol., 2015 Nov , 88 (866-79).
541. Pubmed Liu C. et al. Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expression. J. Biol. Chem., 2015 May 8 , 290 (12048-57).
540. Pubmed Hamada M. et al. Myelin loss and axonal ion channel adaptations associated with gray matter neuronal hyperexcitability. J. Neurosci., 2015 May 6 , 35 (7272-86).
539. Pubmed Han Z. et al. The effects of A-803467 on cardiac Nav1.5 channels. Eur. J. Pharmacol., 2015 May 5 , 754 (52-60).
538. Pubmed Lu V. et al. A 3.7 kb fragment of the mouse Scn10a gene promoter directs neural crest but not placodal lineage EGFP expression in a transgenic animal. J. Neurosci., 2015 May 20 , 35 (8021-34).
537. Pubmed Emery E. et al. Novel SCN9A mutations underlying extreme pain phenotypes: unexpected electrophysiological and clinical phenotype correlations. J. Neurosci., 2015 May 20 , 35 (7674-81).
536. Pubmed Lolignier S. et al. The Nav1.9 channel is a key determinant of cold pain sensation and cold allodynia. Cell Rep, 2015 May 19 , 11 (1067-78).
535. Pubmed Zhu J. et al. Novel heterozygous mutation c.4282G>T in the SCN5A gene in a family with Brugada syndrome. Exp Ther Med, 2015 May , 9 (1639-1645).
534. Pubmed Chahine M. et al. Gating pore current is a novel biophysical defect of Nav1.5 mutations associated with unusual cardiac arrhythmias and dilation. Future Cardiol, 2015 May , 11 (287-91).
533. Pubmed Kalume F. et al. Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome. Neurobiol. Dis., 2015 May , 77 (141-54).
532. Pubmed Marionneau C. et al. Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications. J. Mol. Cell. Cardiol., 2015 May , 82 (36-47).
531. Pubmed Tsai M. et al. Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development. Neurobiol. Dis., 2015 May , 77 (35-48).
530. Pubmed Blanchard M. et al. De novo gain-of-function and loss-of-function mutations of SCN8A in patients with intellectual disabilities and epilepsy. J. Med. Genet., 2015 May , 52 (330-7).
529. Pubmed Wildburger N. et al. Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain. Mol. Cell Proteomics, 2015 May , 14 (1288-300).
528. Pubmed Liu G. et al. Overexpression of SCN5A in mouse heart mimics human syndrome of enhanced atrioventricular nodal conduction. Heart Rhythm, 2015 May , 12 (1036-45).
527. Pubmed Woods C. et al. The phenotype of congenital insensitivity to pain due to the NaV1.9 variant p.L811P. Eur. J. Hum. Genet., 2015 May , 23 (561-3).
526. Pubmed Stadler T. et al. Erythromelalgia mutation Q875E Stabilizes the activated state of sodium channel Nav1.7. J. Biol. Chem., 2015 Mar 6 , 290 (6316-25).
525. Pubmed Tan B. et al. A Brugada syndrome proband with compound heterozygote SCN5A mutations identified from a Chinese family in Singapore. Europace, 2015 Mar 31 , ().
524. Pubmed Han C. et al. Human Nav1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons. J. Neurophysiol., 2015 Mar 18 , (jn.00113.2015).
523. Pubmed Mishra S. et al. Contribution of sodium channel neuronal isoform Nav1.1 to late sodium current in ventricular myocytes from failing hearts. J. Physiol. (Lond.), 2015 Mar 15 , 593 (1409-27).
522. Pubmed Murray J. et al. Engineering Potent and Selective Analogues of GpTx-1, a Tarantula Venom Peptide Antagonist of the NaV1.7 Sodium Channel. J. Med. Chem., 2015 Mar 12 , 58 (2299-314).
521. Pubmed Ossola D. et al. Force-controlled patch clamp of beating cardiac cells. Nano Lett., 2015 Mar 11 , 15 (1743-50).
520. Pubmed Tigerholm J. et al. C-fiber recovery cycle supernormality depends on ion concentration and ion channel permeability. Biophys. J., 2015 Mar 10 , 108 (1057-71).
519. Pubmed Gazina E. et al. 'Neonatal' Nav1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour. Hum. Mol. Genet., 2015 Mar 1 , 24 (1457-68).
518. Pubmed Kong W. et al. SCN8A mutations in Chinese children with early onset epilepsy and intellectual disability. Epilepsia, 2015 Mar , 56 (431-8).
517. Pubmed Yan Z. et al. Expression and functional role of Nav1.9 sodium channel in cartwheel cells of the dorsal cochlear nucleus. Mol Med Rep, 2015 Mar , 11 (1833-6).
516. Pubmed Bechi G. et al. Rescuable folding defective NaV1.1 (SCN1A) mutants in epilepsy: properties, occurrence, and novel rescuing strategy with peptides targeted to the endoplasmic reticulum. Neurobiol. Dis., 2015 Mar , 75 (100-14).
515. Pubmed Rahman W. et al. Osteoarthritis-dependent changes in antinociceptive action of Nav1.7 and Nav1.8 sodium channel blockers: An in vivo electrophysiological study in the rat. Neuroscience, 2015 Jun 4 , 295 (103-16).
514. Pubmed Zhang M. et al. Probing the Redox States of Sodium Channel Cysteines at the Binding Site of μO§-Conotoxin GVIIJ. Biochemistry, 2015 Jun 30 , 54 (3911-20).
513. Pubmed Hoeijmakers J. et al. Painful peripheral neuropathy and sodium channel mutations. Neurosci. Lett., 2015 Jun 2 , 596 (51-9).
512. Pubmed Du Y. et al. Development and validation of a thallium flux-based functional assay for the sodium channel NaV1.7 and its utility for lead discovery and compound profiling. ACS Chem Neurosci, 2015 Jun 17 , 6 (871-8).
511. Pubmed Behr E. et al. Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study. Cardiovasc. Res., 2015 Jun 1 , 106 (520-9).
510. Pubmed Mercier A. et al. Nav1.5 channels can reach the plasma membrane through distinct N-glycosylation states. Biochim. Biophys. Acta, 2015 Jun , 1850 (1215-23).
509. Pubmed Ye P. et al. Scorpion toxin BmK I directly activates Nav1.8 in primary sensory neurons to induce neuronal hyperexcitability in rats. Protein Cell, 2015 Jun , 6 (443-52).
508. Pubmed Fukasawa T. et al. A case of recurrent encephalopathy with SCN2A missense mutation. Brain Dev., 2015 Jun , 37 (631-4).
507. Pubmed Wannous R. et al. Suppression of PPARβ, and DHA treatment, inhibit NaV1.5 and NHE-1 pro-invasive activities. Pflugers Arch., 2015 Jun , 467 (1249-59).
506. Pubmed Stroemlund L. et al. Gap junctions - guards of excitability. Biochem. Soc. Trans., 2015 Jun , 43 (508-12).
505. Pubmed Huang Y. et al. Molecular basis of the inhibition of the fast inactivation of voltage-gated sodium channel Nav1.5 by tarantula toxin Jingzhaotoxin-II. Peptides, 2015 Jun , 68 (175-82).
504. Pubmed Han C. et al. The Domain II S4-S5 Linker in Nav1.9: A Missense Mutation Enhances Activation, Impairs Fast Inactivation, and Produces Human Painful Neuropathy. Neuromolecular Med., 2015 Jun , 17 (158-69).
503. Pubmed Winkel B. et al. The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome. Heart Rhythm, 2015 Jun , 12 (1241-9).
502. Pubmed Daimi H. et al. Regulation of SCN5A by microRNAs: miR-219 modulates SCN5A transcript expression and the effects of flecainide intoxication in mice. Heart Rhythm, 2015 Jun , 12 (1333-42).
501. Pubmed Cai T. et al. Mapping the interaction site for the tarantula toxin hainantoxin-IV (β-TRTX-Hn2a) in the voltage sensor module of domain II of voltage-gated sodium channels. Peptides, 2015 Jun , 68 (148-56).
500. Pubmed Coronas F. et al. Biochemical and physiological characterization of a new Na(+)-channel specific peptide from the venom of the Argentinean scorpion Tityus trivittatus. Peptides, 2015 Jun , 68 (11-6).
499. Pubmed Xu M. et al. An Ankyrin-G N-terminal Gate and Protein Kinase CK2 Dually Regulate Binding of Voltage-gated Sodium and KCNQ2/3 Potassium Channels. J. Biol. Chem., 2015 Jul 3 , 290 (16619-32).
498. Pubmed Talbot S. et al. Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation. Neuron, 2015 Jul 15 , 87 (341-54).
497. Pubmed Torregrosa R. et al. Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels. Bioorg. Med. Chem., 2015 Jul 1 , 23 (3655-66).
496. Pubmed Chow C. et al. Three Peptide Modulators of the Human Voltage-Gated Sodium Channel 1.7, an Important Analgesic Target, from the Venom of an Australian Tarantula. Toxins (Basel), 2015 Jul , 7 (2494-513).
495. Pubmed Slowik D. et al. Benchmarking the stability of human detergent-solubilised voltage-gated sodium channels for structural studies using eel as a reference. Biochim. Biophys. Acta, 2015 Jul , 1848 (1545-51).
494. Pubmed Wang Z. et al. Inhibition of Nav1.7 channels by methyl eugenol as a mechanism underlying its antinociceptive and anesthetic actions. Acta Pharmacol. Sin., 2015 Jul , 36 (791-9).
493. Pubmed Pucca M. et al. Revealing the Function and the Structural Model of Ts4: Insights into the "Non-Toxic" Toxin from Tityus serrulatus Venom. Toxins (Basel), 2015 Jul , 7 (2534-50).
492. Pubmed Wang M. et al. [Dynamic expressions of Nav1.2 and Nav1.6 in hippocampal CA3 region of epileptic rats]. Zhonghua Yi Xue Za Zhi, 2015 Jan 6 , 95 (61-5).
491. Pubmed Zhang J. et al. Electrophysiological and trafficking defects of the SCN5A T353I mutation in Brugada syndrome are rescued by alpha-allocryptopine. Eur. J. Pharmacol., 2015 Jan 5 , 746 (333-43).
490. Pubmed Chong E. et al. Resveratrol, a red wine antioxidant, reduces atrial fibrillation susceptibility in the failing heart by PI3K/AKT/eNOS signaling pathway activation. Heart Rhythm, 2015 Jan 30 , ().
489. Pubmed Fukuoka T. et al. De novo expression of Nav1.7 in injured putative proprioceptive afferents: Multiple tetrodotoxin-sensitive sodium channels are retained in the rat dorsal root after spinal nerve ligation. Neuroscience, 2015 Jan 22 , 284 (693-706).
488. Pubmed Wagnon J. et al. Convulsive seizures and SUDEP in a mouse model of SCN8A epileptic encephalopathy. Hum. Mol. Genet., 2015 Jan 15 , 24 (506-15).
487. Pubmed Saber S. et al. Complex genetic background in a large family with Brugada syndrome. Physiol Rep, 2015 Jan 1 , 3 ().
486. Pubmed Lynch S. et al. Dibenzazepines and dibenzoxazepines as sodium channel blockers. Bioorg. Med. Chem. Lett., 2015 Jan 1 , 25 (43-7).
485. Pubmed Lynch S. et al. N-Aryl azacycles as novel sodium channel blockers. Bioorg. Med. Chem. Lett., 2015 Jan 1 , 25 (48-52).
484. Pubmed Kirchhof P. et al. First report on an inotropic peptide activating tetrodotoxin-sensitive, "neuronal" sodium currents in the heart. Circ Heart Fail, 2015 Jan , 8 (79-88).
483. Pubmed Stoetzer C. et al. Methadone is a local anaesthetic-like inhibitor of neuronal Na+ channels and blocks excitability of mouse peripheral nerves. Br J Anaesth, 2015 Jan , 114 (110-20).
482. Pubmed Zhang F. et al. Natural mutations change the affinity of μ-theraphotoxin-Hhn2a to voltage-gated sodium channels. Toxicon, 2015 Jan , 93 (24-30).
481. Pubmed Rubinstein M. et al. Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome. Neurobiol. Dis., 2015 Jan , 73 (106-17).
480. Pubmed Sato T. et al. Glial reaction in the spinal cord of the degenerating muscle mouse (Scn8a (dmu)). Neurochem. Res., 2015 Jan , 40 (124-9).
479. Pubmed Feng B. et al. Experimental and computational evidence for an essential role of NaV1.6 in spike initiation at stretch-sensitive colorectal afferent endings. J. Neurophysiol., 2015 Feb 4 , (jn.00717.2014).
478. Pubmed Larsen J. et al. The phenotypic spectrum of SCN8A encephalopathy. Neurology, 2015 Feb 3 , 84 (480-9).
477. Pubmed Vandael D. et al. Reduced availability of voltage-gated sodium channels by depolarization or blockade by tetrodotoxin boosts burst firing and catecholamine release in mouse chromaffin cells. J. Physiol. (Lond.), 2015 Feb 15 , 593 (905-27).
476. Pubmed Moreau A. et al. Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy. J. Gen. Physiol., 2015 Feb , 145 (93-106).
475. Pubmed Beltran-Alvarez P. et al. Interplay between R513 methylation and S516 phosphorylation of the cardiac voltage-gated sodium channel. Amino Acids, 2015 Feb , 47 (429-34).
474. Pubmed Ednie A. et al. Sialic acids attached to N- and O-glycans within the Nav1.4 D1S5-S6 linker contribute to channel gating. Biochim. Biophys. Acta, 2015 Feb , 1850 (307-17).
473. Pubmed Zhang H. et al. Reporting sodium channel activity using calcium flux: pharmacological promiscuity of cardiac Nav1.5. Mol. Pharmacol., 2015 Feb , 87 (207-17).
472. Pubmed Suter M. et al. p.L1612P, a novel voltage-gated sodium channel Nav1.7 mutation inducing a cold sensitive paroxysmal extreme pain disorder. Anesthesiology, 2015 Feb , 122 (414-23).
471. Pubmed Bi R. et al. A new hypothesis of sex-differences in temporomandibular disorders: estrogen enhances hyperalgesia of inflamed TMJ through modulating voltage-gated sodium channel 1.7 in trigeminal ganglion? Med. Hypotheses, 2015 Feb , 84 (100-3).
470. Pubmed Jabbari J. et al. Common and rare variants in SCN10A modulate the risk of atrial fibrillation. Circ Cardiovasc Genet, 2015 Feb , 8 (64-73).
469. Pubmed Tikhonov D. et al. State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels. Pflugers Arch., 2015 Feb , 467 (253-66).
468. Pubmed Teramoto N. et al. Selective blocking effects of 4,9-anhydrotetrodotoxin, purified from a crude mixture of tetrodotoxin analogues, on NaV1.6 channels and its chemical aspects. Mar Drugs, 2015 Feb , 13 (984-95).
467. Pubmed Zhu W. et al. Molecular motions that shape the cardiac action potential: Insights from voltage clamp fluorometry. Prog. Biophys. Mol. Biol., 2015 Dec 25 , ().
466. Pubmed Obergrussberger A. et al. Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module. J Lab Autom, 2015 Dec 23 , ().
465. Pubmed Zaharieva I. et al. Loss-of-function mutations in SCN4A cause severe foetal hypokinesia or 'classical' congenital myopathy. Brain, 2015 Dec 22 , ().
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