The N-type calcium channels, also known as a1B or Cav2.2, are high voltage activated (HCA) calcium channels found presynaptically. For a longer introduction, see page 502 in the review . See also the Channelpedia entry for Cav2.1, as this subunit is similar in many respects.
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
neuronal cell body
The portion of a neuron that includes the nucleus, but excludes all cell projections such as axons and dendrites.
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
voltage-gated calcium channel complex
A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
Any of the discrete particles (nerve-ending particles) formed from the clublike presynaptic nerve endings that resist disruption and are snapped or torn off their attachments when brain tissue is homogenized in media isosmotic to plasma.
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
See figure 10 in  for the mechanism of G protein modulation in calcium channels and the effect of palmitoylation on the interaction of Cav-beta subunits with the I–II linker.
Neurokinin 1 Receptor
Unlike R-type channels encoded by CaV2.3, L-type (CaV1.3), N-
type (CaV2.2), and P/Q-type (CaV2.1) channels are inhibited, but
not stimulated, through Neurokinin 1 receptors. 
Beta 3 Subunit
Overexpressed beta 3 subunit (12.5 ng/cell cRNA) significantly suppressed N- and R-type, but not L-type calcium channel currents at holding potentials of 60 and 80 mV.
Roscovitine, a potent inhibitor of cyclin-dependent kinases 1, 2, and 5, slows the deactivation of P/Q (Cav2.1) and N-type (Cav2.2) calcium channels. 
The Cav2.2 subunit consists of
four homologous domains (I–IV), each consisting of six trans-
membrane (TM) segments. The domains are
linked by intracellular loops and have intracellular N and C
termini. (see Fig. 1A) in 
See also figure 7 in  for a structural connection between Cav2.1 and Cav2.2.
Cav2.2 can be found in retinal ganglion cells. 
Cav2.2 control the excitability in retinal ganglion cells and thus are crucial for the development of the visual system. 
The most detailed model can be found in . It is from hippocampal mossy fiber boutons.
For a Hodgkin Huxley rate equation for the Ca2.2 (= N-type) current, see .